Transducer of ERBB2.1 (TOB1) as a Tumor Suppressor: A Mechanistic Perspective

Control of the Normal and Pathological Development of Neural Stem and Progenitor Cells by the PC3/Tis21/Btg2 and Btg1 Genes

(2015) Laura Micheli et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation

(2015) Y-W Zhang et al.   ONCOGENE

SMAD4 Suppresses AURKA-Induced Metastatic Phenotypes via Degradation of AURKA in a TGF -Independent Manner

(2014) L. Jia et al.   MOLECULAR CANCER RESEARCH

MicroRNA-25 promotes gastric cancer migration, invasion and proliferation by directly targeting transducer of ERBB2, 1 and correlates with poor survival

(2014) B-S Li et al.   ONCOGENE

Overexpression of TOB1 confers radioprotection to bronchial epithelial cells through the MAPK/ERK pathway

(2013) JUN CHE et al.   ONCOLOGY REPORTS

Tob1 induces apoptosis and inhibits proliferation, migration and invasion of gastric cancer cells by activating Smad4 and inhibiting β-catenin signaling

(2012) JUTHIKA KUNDU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Inhibition of DNA Damage-induced Apoptosis through Cdc7-mediated Stabilization of Tob

(2012) Toru Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nanog regulates molecules involved in stemness and cell cycle-signaling pathway for maintenance of pluripotency of P19 embryonal carcinoma stem cells

(2012) Seung-Cheol Choi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Antiproliferative protein Tob directly regulates c-myc proto-oncogene expression through cytoplasmic polyadenylation element-binding protein CPEB

(2012) K Ogami et al.   ONCOGENE

Effects of BTG2 on proliferation inhibition and anti-invasion in human lung cancer cells

(2012) Sen Wei et al.   TUMOR BIOLOGY

Suppression of human lung cancer cell proliferation and metastasis in vitro by the transducer of ErbB-2.1 (TOB1)

(2011) Yang Jiao et al.   ACTA PHARMACOLOGICA SINICA

Monoubiquitination of Tob/BTG family proteins competes with degradation-targeting polyubiquitination

(2011) Toru Suzuki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tob, a member of the APRO family, regulates immunological quiescence and tumor suppression

(2011) Dimitrios Tzachanis et al.   CELL CYCLE

Pharmacological Activation of p53 in Cancer Cells

(2011) Mohammad Athar et al.   CURRENT PHARMACEUTICAL DESIGN

Identification of novel subregions of LOH in gastric cancer and analysis of the HIC1 and TOB1 tumor suppressor genes in these subregions

(2011) Jingcui Yu et al.   MOLECULES AND CELLS

EZH2 Depletion Blocks the Proliferation of Colon Cancer Cells

(2011) Bettina Fussbroich et al.   PLoS One

Tob1 is a constitutively expressed repressor of liver regeneration

(2010) Karen J. Ho et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TOB1 Is Regulated by EGF-Dependent HER2 and EGFR Signaling, Is Highly Phosphorylated, and Indicates Poor Prognosis in Node-Negative Breast Cancer

(2009) M. W. Helms et al.   CANCER RESEARCH

A New Look at TCF and β-Catenin through the Lens of a Divergent C. elegans Wnt Pathway

(2009) Bryan T. Phillips et al.   DEVELOPMENTAL CELL

TOB suppresses breast cancer tumorigenesis

(2009) Sean O'Malley et al.   INTERNATIONAL JOURNAL OF CANCER

Structural Basis for the Antiproliferative Activity of the Tob-hCaf1 Complex

(2009) Masataka Horiuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mammalian anti-proliferative BTG/Tob protein family

(2009) G. Sebastiaan Winkler   JOURNAL OF CELLULAR PHYSIOLOGY

BTG/TOB factors impact deadenylases

(2009) Fabienne Mauxion et al.   TRENDS IN BIOCHEMICAL SCIENCES

Tumor growth suppression by adenovirus-mediated introduction of a cell growth suppressing gene tob in a pancreatic cancer model

(2008) Hironobu Yanagie et al.   BIOMEDICINE & PHARMACOTHERAPY

Btg1 and Btg2 gene expression during early chick development

(2008) Andrés Kamaid et al.   DEVELOPMENTAL DYNAMICS

Messenger RNA regulation: to translate or to degrade

(2008) Ann-Bin Shyu et al.   EMBO JOURNAL

The Role of Dbf4/Drf1-Dependent Kinase Cdc7 in DNA-Damage Checkpoint Control

(2008) Toshiya Tsuji et al.   MOLECULAR CELL

Proteasome-mediated degradation of Tob is pivotal for triggering UV-induced apoptosis

(2008) T Suzuki et al.   ONCOGENE