EZH2 Depletion Blocks the Proliferation of Colon Cancer Cells

Regulation of Tumor Angiogenesis by EZH2

(2010) Chunhua Lu et al.   CANCER CELL

The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer

(2010) Liudmila L. Kodach et al.   CARCINOGENESIS

EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-β1 and is a predictor of outcome in ovarian carcinoma patients

(2010) Zhi-Yue Rao et al.   CARCINOGENESIS

CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells

(2010) Yongkun Wei et al.   NATURE CELL BIOLOGY

Deregulation of H3K27 methylation in cancer

(2010) Eva Martinez-Garcia et al.   NATURE GENETICS

Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

(2010) Gorica Nikoloski et al.   NATURE GENETICS

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

(2010) Ryan D Morin et al.   NATURE GENETICS

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

(2010) Thomas Ernst et al.   NATURE GENETICS

Limitations of MTT and MTS-Based Assays for Measurement of Antiproliferative Activity of Green Tea Polyphenols

(2010) Piwen Wang et al.   PLoS One

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

(2010) C. J. Sneeringer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex

(2010) J. D. Pereira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EZH2 and STAT6 expression profiles are correlated with colorectal cancer stage and prognosis

(2010) Cheng-Gang Wang   WORLD JOURNAL OF GASTROENTEROLOGY

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

(2009) W. Fiskus et al.   BLOOD

Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis

(2009) Ø Fluge et al.   BRITISH JOURNAL OF CANCER

Ezh2 Orchestrates Gene Expression for the Stepwise Differentiation of Tissue-Specific Stem Cells

(2009) Elena Ezhkova et al.   CELL

Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expression

(2009) Z L Wu et al.   CELL DEATH AND DIFFERENTIATION

Oncogenic human papillomaviruses block expression of theB-cell translocation gene-2tumor suppressor gene

(2009) Claire Cullmann et al.   INTERNATIONAL JOURNAL OF CANCER

The mammalian anti-proliferative BTG/Tob protein family

(2009) G. Sebastiaan Winkler   JOURNAL OF CELLULAR PHYSIOLOGY

Epigenetic Therapies Move Into New Territory, but How Exactly Do They Work?

(2009) R. S. Tuma   JNCI-Journal of the National Cancer Institute

PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin β1-ERK1/2 and-MMP2 signaling

(2009) Lirong Peng et al.   Molecular Cancer

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

(2009) Aimee L. Jackson et al.   NATURE REVIEWS DRUG DISCOVERY

A Direct Phenotypic Comparison of siRNA Pools and Multiple Individual Duplexes in a Functional Assay

(2009) Brendon D. Parsons et al.   PLoS One

Regulation of Skp2-p27 Axis by the Cdh1/Anaphase-Promoting Complex Pathway in Colorectal Tumorigenesis

(2008) Takeo Fujita et al.   AMERICAN JOURNAL OF PATHOLOGY

Activation of the Enhancer of Zeste Homologue 2 Gene by the Human Papillomavirus E7 Oncoprotein

(2008) D. Holland et al.   CANCER RESEARCH

Regulation of Pancreatic Tumor Cell Proliferation and Chemoresistance by the Histone Methyltransferase Enhancer of Zeste Homologue 2

(2008) A. V. Ougolkov et al.   CLINICAL CANCER RESEARCH

Theenhancer of zeste homolog 2gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells

(2008) Nina Wagener et al.   INTERNATIONAL JOURNAL OF CANCER

Roles of the EZH2 histone methyltransferase in cancer epigenetics

(2008) Jeffrey A. Simon et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS