Journal
ANALYTICAL CHEMISTRY
Volume 83, Issue 8, Pages 3217-3221Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ac2002142
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Funding
- Department of Education, Employment and Workplace Relations, Australia
- Centre for Intelligent Systems Research, Deakin University, Australia
- Foundation for Research Science and Technology (FRST), New Zealand
- Faculty Research and Development Fund, University of Auckland, New Zealand
- MacDiarmid Institute for Advanced Materials and Nanotechnology
- BBSRC
- EPSRC
- Scottish Funding Council, United Kingdom
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Development of the dielectrophoretic (DEP) live cell trapping technology and its interfacing with the environmental scanning electron microscopy (ESEM) is described. DEP microelectrode arrays were fabricated on glass substrate using photolithography and lift-off. Chip-based arrays were applied for ESEM analysis of DEP-trapped human leukemic cells. This work, provides proof-of-concept interfacing of the DEP cell retention and trapping technology with ESEM to provide a high-resolution analysis of individual nonadherent cells.
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