Article
Chemistry, Physical
Qiufeng Meng, Haijun Song, Yong Du, Yufei Ding, Kefeng Cai
Summary: In this study, flexible PC-Ag2Te nanocomposite film was prepared using PEDOT:PSS coated silver telluride nanorods, showing high power factors at different temperatures. The electrical conductivity of the nanocomposite film decreased by only about 3.3% after 1000 bending cycles, indicating good stability. An optimal PC-Ag2Te nanocomposite film assembled thermoelectric generator exhibited high output power and power density at a temperature gradient of 30.3 K.
JOURNAL OF MATERIOMICS
(2021)
Article
Materials Science, Multidisciplinary
Juan Hidalgo Viteri, Nicoleta Cotolan, Lucian Barbu-Tudoran, Graziella Liana Turdean
Summary: A composite film of PEDOT conducting polymer and PA was studied for its release process in artificial saliva solution at different pH values. Electrochemical methods were used for both the preparation of the composite matrix and the investigation of PA release kinetics. The zero-order model provided the best fit for the release process, indicating diffusion control. The EIS method offers high accuracy for characterizing the release profile of materials.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Materials Science, Multidisciplinary
Prem D. Nayak, David Ohayon, Shofarul Wustoni, Sahika Inal
Summary: This study investigates the ORR behavior of a series of electropolymerized PEDOT films and finds that the doping level of the polymer is influenced by the counterion type and the presence of a conductivity enhancer, which controls the ORR pathway in PEDOT films. High levels of intrinsic doping result in films with H2O2 as the major ORR product.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Materials Science, Composites
Lirong Liang, Xiaodong Wang, Miaomiao Wang, Zhuoxin Liu, Guangming Chen, Guoxing Sun
Summary: Organic conductive polymer/carbon nanoparticle thermoelectric composites have attracted attention due to their promising structural and electrical characteristics. By combining chemical oxidative polymerization, acid-treatment of SWCNT, and vacuum filtration, flexible films of PEDOT-Tos/a-SWCNT composites with enhanced TE performance were fabricated. The layered morphology and strong pi-pi interactions between polymer chains and SWCNT contribute to a highly conductive network, while the acid-treatment acts as p-type doping for SWCNT to achieve high electrical conductivity. This study demonstrates the potential for polymer-based composites in TE applications.
COMPOSITES COMMUNICATIONS
(2021)
Article
Chemistry, Inorganic & Nuclear
Dabin Park, Minsu Kim, Jooheon Kim
Summary: This study synthesized a flexible thermoelectric composite film with high performance for potential applications in thermoelectric devices.
DALTON TRANSACTIONS
(2021)
Review
Chemistry, Multidisciplinary
Tian-Run Lv, Wen-Hai Zhang, Ya-Qiong Yang, Jia-Chen Zhang, Ming-Jie Yin, Zhigang Yin, Ken-Tye Yong, Quan-Fu An
Summary: With increasing demands for flexible organic electronic devices, conductive polymers have shown significant breakthroughs in the past decade due to their outstanding conductivity, solution-processing ability, and tailorability. However, commercialization of these devices still lags behind due to performance limitations and limited manufacturing techniques. This review comprehensively summarizes the state-of-the-art technologies for developing organic devices using conductive polymers, including synthesis methods, film fabrication techniques, nanostructure and microstructure tailoring, device applications, and future directions.
Article
Materials Science, Multidisciplinary
Elena Villani, Yanyun Zhang, Zhenghao Chen, Yaqian Zhou, Mariko Konishi, Ikuyoshi Tomita, Shinsuke Inagi
Summary: In this study, we developed poly(3,4-ethylenedioxythiophene)(PEDOT) thin films and their composites, such as PEDOT-copper (PEDOT-Cu) and PEDOT-polythiophene (PEDOT-PT), on a nonconductive substrate using AC-bipolar electropolymerization. These films were then utilized as wireless electrodes for the generation of luminol electrochemiluminescence (ECL). The intensity and spatial distribution of the ECL light emission were found to be correlated with the conductivity and composition of the different polymer films.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Polymer Science
Siqi Wu, Yihan Wang, Lizhi Hu, Qiang Yin, Kai Du, Qinjian Yin, Libin Huang
Summary: The study focused on the preparation and thermoelectric properties of poly(3,4-ethylenedioxythiophene): poly(styrenesulfonate)/copper phthalocyanine disulfonic acid (PEDOT: PSS/CuPc-[SO3H](2)) composite films. It was found that CuPc-(SO3H)(2) as a dopant significantly improved the thermoelectric properties of the composites.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Polymer Science
Aleksandra O. Efremova, Elena G. Tolstopjatova, Rudolf Holze, Veniamin V. Kondratiev
Summary: The cyclic voltammograms and optical absorption spectra of PEDOT/WO3 composite films were analyzed to understand the interactions between the components. The presence of conducting polymer in the composite accelerates reversible redox processes, while there are no significant changes in the electronic absorption bands. The electrostatic interactions in the composite do not alter the opto-electronic properties, but result in a redistribution of polaron and bipolaron forms within the polymer.
Article
Chemistry, Physical
Xudong Liu, Xiaoxiao Zhao, Jing Yan, Ying Huang, Tiehu Li, Panbo Liu
Summary: Fe3O4@PEDOT/rGO composite with efficient EM wave absorption properties is prepared in this study. The composite shows enhanced absorption performance with a wide effective absorption bandwidth, and the absorption mechanism is explained in detail.
Article
Chemistry, Physical
Wen Chen, Han Xiao, Xufeng Zhou, Xueyan Xu, Shunqiong Jiang, Zhihong Qin, Shiyun Ding, Cancan Bian, Zhaoping Liu
Summary: Graphene films have high electrical conductivity and good mechanical strength, making them ideal for use in supercapacitors. However, their low elastic deformation ability limits their application in stretchable supercapacitors. By combining graphene with a conductive polymer hydrogel, the resulting composite film exhibits improved ductility and higher specific capacitance. A proof-of-concept planar supercapacitor using this graphene-conductive polymer hydrogel composite film as electrodes retains excellent electrochemical performance even under stretching conditions.
ACS APPLIED ENERGY MATERIALS
(2022)
Article
Materials Science, Characterization & Testing
Yihan Wang, Siqi Wu, Qinjian Yin, Bo Jiang, Site Mo
Summary: The study on poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate)/polyaniline (PEDOT:PSS/PANi) composite films shows that the nanostructured PANi, particularly nanoflakes, with planar molecule structure lead to the best crystallinity and highest thermoelectric properties. Additionally, the interaction between PEDOT and PANi in the composite films significantly enhances the electrical conductivity, highlighting the importance of their arrangement in influencing the overall performance.
Article
Electrochemistry
Aleksei Kubarkov, Zhanna A. Boeva, Tom Lindfors, Vladimir G. Sergeyev
Summary: Microstructured composite films based on PEDOT and nGO were prepared by electrochemical methods, with nGO successfully incorporated into PEDOT as nano sheets, leading to enhanced electrochemical activity of the resulting PEDOT:nRGO films.
ELECTROCHIMICA ACTA
(2021)
Article
Chemistry, Physical
Shiwei Liu, Kai Li, Qingyi Shen, Dandan Shao, Shansong Huang, Youtao Xie, Xuebin Zheng
Summary: In this study, MnO2-PEDOT composite nanocoatings were prepared on metallic implants, showing improved electrochemical properties and mechanical stability. They significantly enhanced cellular adhesion, proliferation, and differentiation, indicating potential applications in bone tissue engineering.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Physical
James Kumankuma-Sarpong, Wei Guo, Yongzhu Fu
Summary: The PEDOT@YVO composite is reported as a stable cathode material for AZIBs, showing improved crystalline structure and higher initial specific capacity than pure YVO. This composite electrode demonstrates effective electric conductivity and long-term stable discharge-charge cycle performance, with retention of capacity significantly better than that of YVO. The oxygen vacancies and improved electrical conductivity of the composite contribute to its invigorated electrochemical performance, providing another avenue for enhancing the electrochemical properties of AZIBs.
Article
Chemistry, Multidisciplinary
Maria Chiara Sportelli, Rosaria Anna Picca, Margherita Izzi, Nicola Cioffi
Summary: This study presents a straightforward method to synthesize copper sub-microparticles with a green core-shell structure using poly(n-vinyl)pyrrolidone (PVP) as stabilizer. Copper sulfate pentahydrate and glucose were used as precursor and reducing agent, respectively, to prepare Cu@PVP colloids. The presence of PVP eliminated the need for an inert atmosphere during the synthesis, simplifying the process. The morphology and spectroscopic properties of the Cu@PVP colloids were characterized, confirming the formation of a PVP layer around the copper core. These colloids were further utilized in composite thin films for potential antimicrobial applications in combination with a recyclable polymer, polycarbonate (4,4'-(1-methylethylidene)bis(phenol)).
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Food Science & Technology
Jean Henrottin, Rosa Pilolli, Anne-Catherine Huet, Christof van Poucke, Chiara Nitride, Marc De Loose, Olivier Tranquet, Colette Larre, Karine Adel-Patient, Herve Bernard, E. N. Clare Mills, Nathalie Gillard, Linda Monaci
Summary: Developing reliable methodologies for detecting and quantifying allergens in processed food is crucial. This study focused on optimizing the sample preparation protocol for allergen detection in chocolate, a complex food matrix. Different steps of the protocol were considered and the best performing method was identified.
Article
Electrochemistry
Margherita Izzi, Maria Chiara Sportelli, Rosaria Anna Picca, Nicola Cioffi
Summary: The present study proposes a one-step synthesis of Zn/Ca hybrid nano-oxides combining an electrochemical route to ZnO nanostructures with the wet chemical production of Ca(OH)(2) nanostructures. The nanocoating prepared with Zn-Ca0.1 exhibited a Zn2+ release increasing up to 1 mu mol cm(-2) in 24 h, while Zn-Ca0.4-based nanocoatings released a constant value of about 0.35 mu mol/cm(2). Both types of nanocoatings showed good antimicrobial activity against Bacillus subtilis after 48 h and hydrophilic behavior over 28 days.
Article
Infectious Diseases
Syed Imdadul Hossain, Diellza Bajrami, Maria Chiara Sportelli, Rosaria Anna Picca, Annalisa Volpe, Caterina Gaudiuso, Antonio Ancona, Luigi Gentile, Gerardo Palazzo, Nicoletta Ditaranto, Boris Mizaikoff, Nicola Cioffi
Summary: The aim of this study is to develop a green and multifunctional antibiofilm water-insoluble coating with laser-ablated Ag NPs (L-Ag NPs) and montmorillonite (MMT). The characterization confirmed the successful incorporation of L-Ag NPs into MMT and the contact and deposition of Ag NPs onto the surface. The controlled release of Ag ions from the L-Ag/MMT/beeswax coating was supported by the antimicrobial ion release kinetic profile.
Review
Nutrition & Dietetics
Laura Quintieri, Chiara Nitride, Elisabetta De Angelis, Antonella Lamonaca, Rosa Pilolli, Francesco Russo, Linda Monaci
Summary: The increasing global population and shortage of proteinaceous ingredients have driven the international community to search for new sustainable protein resources. This review evaluates insect proteins, underutilized legume crops, aquatic weeds, and fungi as alternative protein sources. It also discusses the safety issues and functional characteristics of these proteins, including their incorporation in food products and their impact on future consumer trends towards vegetarianism or veganism.
Review
Chemistry, Multidisciplinary
Syed Imdadul Hossain, Ekaterina A. Kukushkina, Margherita Izzi, Maria Chiara Sportelli, Rosaria Anna Picca, Nicoletta Ditaranto, Nicola Cioffi
Summary: This review provides a comprehensive overview of Ag-, Cu-, and ZnO-modified MMT, including preparation methods, materials characterization, mechanisms of action, antimicrobial activity on different bacterial strains, real life applications, and environmental and toxicity issues.
Article
Pharmacology & Pharmacy
Adriana Trapani, Stefano Castellani, Lorenzo Guerra, Elvira De Giglio, Giuseppe Fracchiolla, Filomena Corbo, Nicola Cioffi, Giuseppe Passantino, Maria Luana Poeta, Pasqualina Montemurro, Rosanna Mallamaci, Rosa Angela Cardone, Massimo Conese
Summary: We have successfully formulated solid lipid nanoparticles (SLNs) containing dopamine (DA) and grape-seed-derived proanthocyanidins (GSE) for Parkinson's disease (PD) treatment. The combination of GSE and DA has a synergistic effect in reducing PD-related oxidative stress. Two methods of DA/GSE loading were studied, and it was found that coencapsulating GSE resulted in smaller SLN size and higher cellular uptake compared to adsorbing GSE onto preformed DA containing SLNs.
Article
Food Science & Technology
Anna Luparelli, Ilario Losito, Elisabetta De Angelis, Rosa Pilolli, Linda Monaci
Summary: Due to the increasing global incidence of allergy to nuts and peanuts, this paper describes the development of a multi-target method based on LC-MS, MS/MS to detect traces of five nuts species and peanuts in a bakery product. The method utilizes the LC-MS responses of selected peptides resulting from digestion of allergenic proteins, allowing for quantification down to mg·kg(-1) levels in the model cookie. This opens up interesting possibilities for quantifying hidden nuts/peanuts in bakery products and improving precautionary labelling.
Review
Nanoscience & Nanotechnology
Margherita Izzi, Maria C. C. Sportelli, Luisa Torsi, Rosaria A. A. Picca, Nicola Cioffi
Summary: ZnO nanostructures (NSs) show significant antimicrobial activity and are highly biocompatible, chemically stable, and low in toxicity. This review focuses on the preparation and antimicrobial use of ZnO NSs. Different synthesis approaches including sol-gel, hydrothermal, biogenic, and electrochemical methods are discussed, along with their scalability, simplicity, and efficacy. The application of ZnO NSs in various fields and their antimicrobial mechanisms of action, cell resistance, and cytotoxicity are also highlighted. Additionally, the future prospects of ZnO NSs in this application field are addressed.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Medicinal
Ojaswitha Ommi, Niccolo Paoletti, Alessandro Bonardi, Paola Gratteri, Harshada Anil Bhalerao, Shashikanta Sau, Srinivas Nanduri, Arifuddin Mohammed, Nitin Pal Kalia, Rajesh Sonti, Claudiu T. Supuran, Venkata Madhavi Yaddanapudi
Summary: In this study, two series of pyrazole-tethered sulfamoyl phenyl acetamides and pyrazole-tethered sulfamoyl phenyl benzamides were designed and synthesized. The synthesized compounds were evaluated for their inhibitory activity against human carbonic anhydrases (hCA) I and II, and the carbonic anhydrases of Mycobacterium tuberculosis (mtCA) 1-3. The results showed that certain compounds exhibited selective inhibition against specific enzymes, such as compound 6g showing significant and selective inhibition toward hCA I and II. Compound 5g exhibited the best inhibition toward mtCA 2. Docking studies further supported the selectivity of these compounds.
ARCHIV DER PHARMAZIE
(2023)
Article
Chemistry, Medicinal
Shaik Mahammad Ghouse, Kareena Sinha, Alessandro Bonardi, Gaurav Pawar, Satyaveni Malasala, Srikanth Danaboina, Arifuddin Mohammed, Venkata M. Yaddanapudi, Claudiu T. Supuran, Srinivas Nanduri
Summary: Carbonic anhydrase isoforms IX and XII are highly expressed in hypoxic tumor cells and play a role in cancer onset and spread. Coumarin derivatives were found to selectively inhibit these isoforms, offering a promising strategy for anticancer therapy. This study identified 6-aminocoumarin sulfonamide and oxime ether derivatives as potent inhibitors of human carbonic anhydrase IX and XII. The results demonstrate the potential of these derivatives as selective inhibitors and provide a foundation for further development as anticancer agents.
ARCHIV DER PHARMAZIE
(2023)
Article
Biochemistry & Molecular Biology
Ojaswitha Ommi, Mohammad Naiyaz Ahmad, Siva Nageswara Rao Gajula, Parita Wanjari, Shashikanta Sau, Puja Kumari Agnivesh, Santosh Kumar Sahoo, Nitin Pal Kalia, Rajesh Sonti, Srinivas Nanduri, Arunava Dasgupta, Sidharth Chopra, Venkata Madhavi Yaddanapudi
Summary: In this study, 1,3-diaryl substituted pyrazole-based urea and thiourea derivatives were designed, synthesized, and evaluated for their antimicrobial activity. Compound 7a showed potent activity against S. aureus, while compound 7j exhibited activity against Mycobacterium tuberculosis. Both compounds were non-toxic to Vero cells and had good microsomal stability. Compound 7a showed equipotent activity against various multidrug-resistant strains of S. aureus and inhibited DNA gyrase supercoiling activity. Molecular modeling studies suggested that compound 7a binds to the active site of DNA gyrase with good affinity.
RSC MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Gaurav Pawar, Shaik Mahammad Ghouse, Swanand Vinayak Joshi, Md Naiyaz Ahmad, Arunava Dasgupta, Venkata Madhavi Yaddanapudi, Siddharth Chopra, Srinivas Nanduri
Summary: An improved microwave irradiation protocol using copper iodide as a catalyst was developed for synthesizing pyrido[2,1:2,3]imidazo[4,5-c]quinoline. The proposed mechanism was supported by DFT and ESI-HRMS studies. Among the synthesized derivatives, compounds 3k, 3o, 3u, and 3w showed antimycobacterial activity against M. tuberculosis H37Rv ATCC 27294. An in silico ADMET profile was performed to assess the active compound's safety and efficacy.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Nanoscience & Nanotechnology
Syed Imdadul Hossain, Maria Chiara Sportelli, Rosaria Anna Picca, Luigi Gentile, Gerardo Palazzo, Nicoletta Ditaranto, Nicola Cioffi
Summary: This study successfully synthesized green, facile, scalable, reproducible, and stable silver chloride/benzyldimethylhexadecyl-ammonium chloride (AgCl/BAC) colloidal nanoantimicrobials using a simple method similar to chemistry lab titration. The morphology and stability of the nanocolloids were investigated, and it was found that the AgCl/BAC nanoantimicrobials likely have synergistic antimicrobial properties. The experimental evidence also supports the morphological stability and long-term antimicrobial effect of the AgCl/BAC nanoantimicrobials.
ACS APPLIED BIO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Nitesh Tamang, Christopher Andrews, Sai Kiran Mavileti, Srinivas Nanduri, Nageswara Rao Golakoti, Balasubramanyam Karanam
Summary: Acetals of andrographolide, 14-deoxy-12-hydroxyandrographolide, and isoandrographolide were synthesized using benzaldehyde and heteroaromatic aldehydes. These compounds exhibited promising anticancer activity, with benzaldehyde-derived acetals of andrographolide showing the highest growth inhibition against leukemia cancer cells. Furthermore, a specific compound showed the best activity against breast cancer cells.
NEW JOURNAL OF CHEMISTRY
(2022)
