Article
Materials Science, Multidisciplinary
Dong Xie, Chunling Xu, Xiwei Yao, An Min Wang
Summary: The quantum version of a special classical Wheatstone bridge has been proposed, which is built with a boundary-driven spin system. We introduce a quantum Wheatstone bridge consisting of Bose systems, capable of simulating the general classical Wheatstone bridge. Balancing the quantum Wheatstone bridge can result in obtaining an unknown coupling, determined through homodyne detection. The precision of measurement is optimal when the quantum Wheatstone bridge is balanced, as shown by calculating the quantum Fisher information. Additionally, homodyne detection is an effective measurement method in low-temperature environments.
RESULTS IN PHYSICS
(2023)
Article
Engineering, Electrical & Electronic
Yuanfei Zhang, Fenglei Ni, Hong Liu
Summary: A novel Wheatstone bridge adjustment circuit with both rough-tuning and fine-tuning functions is designed. The circuit consists of parametric circuit structure, rough-tuning sub-circuit with series-parallel-resistor (SPR) structures, and fine-tuning sub-circuit with a resistor and a digital-to-analog converter (DAC). The circuit effectively eliminates bridge imbalance in the manufacturing stage and compensates for additional imbalance in the application stage caused by external factors. The effectiveness of the circuit is verified on a six-axis force/torque sensor developed for the Chinese Space Station.
IEEE SENSORS JOURNAL
(2023)
Article
Engineering, Electrical & Electronic
Ting Li, Haiping Shang, Qunying Zhang, Weibing Wang
Summary: By changing the longitudinal resistance and transverse resistance, the nonlinearity of pressure sensors can be effectively reduced, and a method for optimizing the nonlinearity of piezoresistive pressure sensors was proposed, which could reduce nonlinearity by several orders of magnitude in simulation.
MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS
(2021)
Article
Materials Science, Multidisciplinary
Mubbashar Nazeer, Farooq Hussain, Mustafa Turkyilmazoglu, Zulfiqar Ali
Summary: This article investigates electro-osmotic flows (EoF) in inclined channels using a differential type non-Newtonian fluid model. Highly viscous bi-phase fluid flows are considered, with two different metallic particles as the dispersed phase. The study formulates nonlinear differential equations accounting for the stress tensor, Poisson equation, and Debye length approximation. Comparative analysis shows good agreement with previous investigations, and a parametric study reveals differences in momentum between the fluid phase and particles phase. The study highlights the applications in petroleum and gas engineering.
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
(2023)
Article
Biochemical Research Methods
Simon J. Haward, Cameron C. Hopkins, Stylianos Varchanis, Amy Q. Shen
Summary: Flow around a cylinder is a classical problem in fluid dynamics and important for understanding microscale industrial and biological processes. Recent studies on model microfluidic geometries have provided insights into novel flow instabilities in viscoelastic flows.
Article
Engineering, Electrical & Electronic
Yucai Xie, Haotian Shi, Hongpeng Zhang, Shuang Yu, Lebile Llerioluwa, Yiwen Zheng, Guobin Li, Yuqing Sun, Haiquan Chen
Summary: A bridge-type inductance sensor with a two-stage filter circuit is proposed for high-precision detection of metal debris in oil. The sensor utilizes a Wheatstone bridge structure sensing unit and a circuit with rectification, amplitude modulation, and amplification functions to improve detection accuracy and extract weak abrasive signals submerged in noise. By adjusting the passband gain of the two-stage filter circuit, the measurement range of the sensor voltage value is improved, providing technical support for fault diagnosis and prevention in hydraulic systems.
IEEE SENSORS JOURNAL
(2021)
Article
Engineering, Environmental
Wenyi Deng, Jie Zhou, Li Yu, Sirui Pan, Jiamin Xiao, Zhichen Lai, Yaxin Su
Summary: This study aims to reduce sludge-to-wall adhesion by forming a water layer induced by boundary electro-osmotic pulse (BEOP). The effects of various parameters on adhesive stress of sewage sludge with different moisture content were studied, along with investigations on the migration of water, ions, and organic matters to explore the functional mechanism of BEOP.
Article
Computer Science, Hardware & Architecture
Katsurou Takahashi, Hiroaki Ohshima
Summary: The study proposes a method for synonym search by utilizing transformation matrix word vectors to address analogical problems over time, showcasing experiments for evaluation using nDCG and MRR metrics.
JOURNAL OF SUPERCOMPUTING
(2021)
Article
Engineering, Electrical & Electronic
Nan Lv, Wenbo Jiang, Kongsen Hu, Zhiwei Lyu
Summary: This study demonstrates a promising strategy to fabricate nanoscale, highly sensitive, and low-cost integrated sensing materials through coaxial electrospinning. The integrated core-shell nanofibers show high sensitivity and quick response without the need for layer electrodes.
ACS APPLIED ELECTRONIC MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Chenyu Wen, Eva Bertosin, Xin Shi, Cees Dekker, Sonja Schmid
Summary: In this study, we achieved strong trapping and extended observation of single proteins using site specific cholesterol functionalization on a lipid-coated nanopore. This greatly enhances the trapping capacity and extends the observation time.
Article
Physics, Applied
N. Stanojevic, D. K. Markushev, S. M. Aleksic, D. S. Pantic, S. P. Galovic, D. D. Markushev, J. Ordonez-Miranda
Summary: By analogizing resistor-capacitor (RC) filters and the thermoelastic component of a photoacoustic signal, the complex thermoelastic response of an open photoacoustic cell is described as a simple linear time-invariant system of a low-pass RC filter. A linear relation between the thermoelastic cut-off frequency and sample material thickness within the range of 10-1000 μm is found to establish this description. Numerical simulations and experimental validation using an open photoacoustic cell setup confirm the linear dependence of the thermoelastic cut-off frequency on the sample thickness, providing a basis for a new method of thermal material characterization.
JOURNAL OF APPLIED PHYSICS
(2023)
Article
Mathematics, Interdisciplinary Applications
Faisal Z. Duraihem, Mubbashar Nazeer, Farooq Hussain, S. Saleem
Summary: This article presents an electro-osmotic particulate flow in a bulged out cavity. Casson non-Newtonian fluid model is used as the base liquid, and spherical & homogenous metallic particles form a granular suspension. The motion of the particles is simulated using Navier-Stokes equations. The study highlights the applications of electro-osmosis in various fields.
COMPUTATIONAL PARTICLE MECHANICS
(2023)
Article
Mechanics
Di Li, Xiangchun Xuan
Summary: This study investigates particle migration in microfluidic manipulation, showing that particles migrate towards the centerline and corners in a viscoelastic flow. The migration is influenced by polymer length.
Article
Engineering, Chemical
Mengqi Li, Theofilos Boulafentis, Antonios Stathoulopoulos, Zhaomiao Liu, Stavroula Balabani
Summary: The role of elasticity on the flow topology inside viscoelastic (Boger) droplets moving in a rectangular micro-channel is experimentally examined using micro Particle Image Velocimetry (μPIV). The results show that varying the Wi number alters the flow topology inside the droplets, and when the Wi and elastic number increase, a new flow structure is observed characterized by two recirculating regions. These findings highlight the importance of elasticity in microdroplet flows and the potential of tuning elasticity for microfluidic applications.
CHEMICAL ENGINEERING SCIENCE
(2023)
Article
Chemistry, Physical
Baohua Tian, Haiping Shang, Weibing Wang
Summary: This study analyzed the factors affecting temperature zero drift in SiC piezoresistive pressure sensors and proposed an asymmetric Wheatstone bridge to effectively compensate for temperature drift, improving sensor performance and measurement accuracy.
Article
Materials Science, Multidisciplinary
Rongxiang He, Meilin Ruan, Yuyang Qi, Hongni Liu, Zhengtao Zhang, Chaohui Chen, Yiping Chao, Yumin Liu, Yong Chen
ADVANCED ENGINEERING MATERIALS
(2020)
Article
Chemistry, Analytical
Zhenting Zhao, Yongjiao Sun, Jinxiang Song, Yajia Li, Yun Xie, Han Cui, Weiping Gong, Jie Hu, Yong Chen
Summary: A highly sensitive nonenzymetic electrochemical glucose sensor was developed using a multicomponent sensing electrode made of nickel cobalt layered double hydroxide and cobalt copper carbonate hydroxide on Cu foam. The sensor exhibited high sensitivity, large linear concentration range, and fast response times for glucose detection, making it applicable for micromole level glucose determination.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Nanoscience & Nanotechnology
Boxin Huang, Juan Peng, Xiaochen Huang, Feng Liang, Li Wang, Jian Shi, Ayako Yamada, Yong Chen
Summary: The research focuses on a method to generate interconnected neural clusters in a multiscale scaffold, leading to the formation of two types of neural clusters and indicating the complexity of neural-scaffold interaction and the variability of neural organization.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Engineering, Biomedical
Sisi Li, Momoko Yoshioka, Junjun Li, Li Liu, Shixin Ye, Ken-ichiro Kamei, Yong Chen
Summary: A casting method is developed to replicate the nanofibrous morphology onto a thin layer of PDMS, which proves to be a flexible and cost-effective approach for propagating hiPSCs.
BIOMEDICAL MATERIALS
(2022)
Article
Engineering, Biomedical
Yong He, Elrade Rofaani, Xiaochen Huang, Boxin Huang, Feng Liang, Li Wang, Jian Shi, Juan Peng, Yong Chen
Summary: A method using human induced pluripotent stem cells and artificial basement membrane to generate alveolar epithelium is presented. The alveolar epithelium achieved high-level expressions of specific proteins and characteristic tight junctions. Additionally, the method can potentially be applied to other types of artificial epithelium and endothelium.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Engineering, Biomedical
Elrade Rofaani, Yong He, Juan Peng, Yong Chen
Summary: This study developed a method to overcome the lack of in vivo-like basement membrane (BM) for in vitro modeling by culturing primordial lung progenitors (PLPs) on an artificial basement membrane (ABM) composed of collagen IV and laminin. The forces generated by the growing epithelial monolayer on the ABM led to geometry-dependent folding and enhanced expression of surfactant protein C and aquaporin 5 compared with a nanofiber-covered substrate. This work emphasizes the importance of recapitulating natural BM for advanced epithelial modeling.
ACTA BIOMATERIALIA
(2023)
Article
Engineering, Biomedical
Wang Xi, Jad Saleh, Ayako Yamada, Caterina Tomba, Barbara Mercier, Sebastien Janel, Tien Dang, Matis Soleilhac, Aurelie Djemat, Huiqiong Wu, Beatrice Romagnolo, Frank Lafont, Rene-Marc Mege, Yong Chen, Delphine Delacour
Summary: This study developed hydrogel scaffolds with different elasticities and investigated their influence on the expansion, organization, and differentiation of intestinal epithelial cells. The results showed that cells on soft substrates exhibited improved characteristics resembling in vivo intestinal tissue, which is of significant importance for the design of biomaterials for ex vivo intestinal models.
Article
Biochemistry & Molecular Biology
Elrade Rofaani, Boxin Huang, Feng Liang, Juan Peng, Yong Chen
Summary: This study successfully generated airway epithelium using artificial basement membrane (ABM) and human-induced pluripotent stem cells (hiPSCs). The generated pseudostratified airway epithelium consists of multiple cell types and demonstrates advantages over other methods.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Materials Science, Biomaterials
Xiaochen Huang, Boxin Huang, Yong He, Liang Feng, Jian Shi, Li Wang, Juan Peng, Yong Chen
Summary: SARS-CoV-2 may cause molecular and functional changes in cardiomyocytes through the interaction with ACE2 complex. The spike proteins of SARS-CoV-2 can lead to abnormal sarcomere structures and disrupted gap junction protein distribution in human-induced pluripotent stem cell-derived cardiomyocytes. Additionally, the damage to cardiomyocytes caused by spike proteins is enhanced when angiotensin II is added, resulting in potential cardiac dysfunction.
Article
Engineering, Biomedical
Boxin Huang, Yong He, Elrade Rofaani, Feng Liang, Xiaochen Huang, Jian Shi, Li Wang, Ayako Yamada, Juan Peng, Yong Chen
Summary: The study introduced a method for directed differentiation of hiPSCs using nanofiber membranes, resulting in the formation of regular and interconnected cortical neural clusters. By modulating the substrate stiffness and permeability, cells were concentrated in the central area of the honeycomb compartments, with synchronized neural activities. Compared to other types of substrates, nanofiber membranes were more efficient in promoting cell self-organization and neural activities.
ACTA BIOMATERIALIA
(2022)
Article
Materials Science, Biomaterials
Changchong Chen, Zeinab Ibrahim, Marion F. Marchand, Tristan Piolot, Sahil Kamboj, Franck Carreiras, Ayako Yamada, Marie-Claire Schanne-Klein, Yong Chen, Ambroise Lambert, Carole Aime
Summary: Cellular heterogeneity plays a critical role in various physiological processes, and the extracellular matrix (ECM) is crucial for generating this heterogeneity. The researchers have developed ECM models that allow independent control of protein composition, topology, and stiffness, which can recreate the complex phenotypic landscape of ovarian cancer cells.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2022)
Article
Nanoscience & Nanotechnology
Feng Tian, Linlin Yin, Peiran Lin, Yurong Liu, Wenlong Wang, Yong Chen, Yadong Tang
Summary: In this study, a micro-/nanohierarchical substrate was fabricated using soft lithography and electrospinning to evaluate the synergistic effect of aligned nanofibrous topographical guidance and off-ground culture environment on the formation of endothelium and maturation of hiPSC-CMs. The study showed that the micro-/nanohierarchical substrate enhanced the proliferation, alignment, and cell-cell interaction of HUVECs, as well as the sarcomere length and maturation-related gene expression of hiPSC-CMs. Moreover, hiPSC-CMs on the substrate displayed higher resistance to cardiac drugs compared to other groups, indicating higher maturity. Overall, the proposed substrate holds great potential for in vitro models and tissue engineering.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Biophysics
Xiaochen Huang, Feng Liang, Boxin Huang, Haoyue Luo, Jian Shi, Li Wang, Juan Peng, Yong Chen
Summary: Recent advances have shown that electrochemical impedance spectroscopy is highly sensitive in real-time monitoring of cell barriers on a chip. In this study, the method was applied to investigate the hiPSC derived and ABM-supported endothelial barrier. The results showed enhanced stability of the BMEC barrier in a serum-free and BrdU-containing culture medium compared to conventional culture, and the barrier was sensitive to stimuli such as thrombin. This method can be advocated for investigating cell barrier integrity and barrier-based assays.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Engineering, Electrical & Electronic
Changchong Chen, Yong He, Elliot Lopez, Franck Carreiras, Ayako Yamada, Marie-Claire Schanne-Klein, Ambroise Lambert, Yong Chen, Carole Aime
Summary: We developed an invasion assay using microfabricated culture devices that can control the number and size of spheroids. We observed spheroid disruption due to substrate-induced cell migration. This method holds potential for tumor modeling and anti-cancer drug development.
MICRO AND NANO ENGINEERING
(2022)
Article
Engineering, Electrical & Electronic
Feng Liang, Juan Peng, Jian Shi, Li Wang, Carole Aime, Yong Chen
Summary: This study presents a method utilizing a microfluidic device to capture and release rare cells. By applying reverse flow and adding micro particles, the efficiency of capture and release can be improved.
MICRO AND NANO ENGINEERING
(2022)