Article
Chemistry, Analytical
Wanwisa Deenin, Abdulhadee Yakoh, Chahya Kreangkaiwal, Orawon Chailapakul, Kanitha Patarakul, Sudkate Chaiyo
Summary: In this study, an integrated lateral-flow immunoassay with an electrochemical readout (eLFIA) was developed for early-stage detection of LipL32, a protein present only in pathogenic Leptospira species. The eLFIA showed superior performance in terms of a low detectable limit and a broad linear dynamic range. The test strip provided a straightforward and sensitive approach for the diagnosis of leptospirosis.
ANALYTICAL CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Yantao Wu, Sajant Anand, Sheng-Hsuan Lin, Frank Pollmann, Michael P. Zaletel
Summary: This article introduces a new class of isometric tensor network state (isoTNS) that allows for efficient simulation of 2D systems on finite square lattices. By using infinite strip geometries and the Moses Move algorithm, an infinite MPS representation of a 2D quantum state can be transformed into a strip isoTNS, and the entanglement properties and local observables of the resulting state can be investigated.
Article
Operations Research & Management Science
Stephane Grandcolas, Cyril Pain-Barre
Summary: This paper presents a hybrid metaheuristic approach called PVS for the two-dimensional strip packing problem, which relies on a local search algorithm and an exact procedure. PVS follows a specific anytime strategy to continuously improve the current solution until it is provably optimal or reaches a given time limit. Experimental results show that the method is competitive on moderate-sized instances.
ANNALS OF OPERATIONS RESEARCH
(2022)
Article
Multidisciplinary Sciences
Hye Min Seo, Seulwoo Kim, Sangwoo Kwon, YongJoo Kim, Minchul Sung, Jongryeol Yang, Boryeong Lee, Jongbaek Sung, Min -Ho Kang, Jungwon Park, Kyounghee Shin, Won Bo Lee, Jin Woong Kim
Summary: A smart polymer laminate film system with direction-controlled phase separation behavior was developed in this study, where liquid nanodrops were uniformly confined in a polymer laminate film through the layer-by-layer deposition of oppositely charged emulsion nanodrops and polyelectrolytes.
Article
Computer Science, Interdisciplinary Applications
Carlos Diego Rodrigues, Adriana Cristina Cherri, Silvio Alexandre de Araujo
Summary: This paper presents a new mixed integer programming formulation for solving two-dimensional guillotine cutting and packing problems. The formulation is based on a strip decomposition of the rectangular spaces and covers most of the related problems in the literature, allowing for an arbitrary number of stages. Computational experiments show that the proposed formulation, both in heuristic and exact versions, outputs competitive results in terms of computational time and percentage of optimally solved instances.
COMPUTERS & OPERATIONS RESEARCH
(2023)
Article
Computer Science, Artificial Intelligence
Alvaro Neuenfeldt Jr, Julio Siluk, Matheus Francescatto, Gabriel Stieler, David Disconzi
Summary: This article presents a framework for fitting classification models based on supervised machine learning techniques to select improvement heuristics for the rectangular 2D strip packing problem. With extensive training and testing using a large number of problem instances, the framework demonstrates accurate prediction capability and potential for application.
EXPERT SYSTEMS WITH APPLICATIONS
(2023)
Article
Mathematics
Kaiyuan Liu, Hongyu Zhang, Chong Wang, Hui Li, Yongquan Chen, Qiong Chen
Summary: This paper proposes a robust optimization model for the uncertain 2D-SPP problem and validates its effectiveness and efficiency through comprehensive experiments.
Article
Mathematics
Kaijian Sha, Yun Wang, Chunjing Xie
Summary: In this paper, the authors prove the uniform nonlinear structural stability of Poiseuille flows with arbitrarily large flux in a two-dimensional periodic strip. They establish the a priori estimate for the corresponding linearized problem by analyzing the associated boundary layers. The well-posedness theory for the Navier-Stokes system is also proved, even when the L2-norm of the external force is large. These results demonstrate the uniqueness of solutions for the steady Navier-Stokes system, even when the flux is large and the flow is not symmetric.
JOURNAL OF DIFFERENTIAL EQUATIONS
(2023)
Article
Medicine, General & Internal
Thulaganyo Domfe, Zikhona Njengele-Tetyana, Nikiwe Mhlanga, Phumlani Tetyana, Amanda Skepu, Jane Catherine Ngila, Lucky Mashudu Sikhwivhilu
Summary: Rift Valley fever is a mosquito-borne zoonotic disease that poses a dual threat to public health and livestock production. A lateral flow assay device capable of detecting antibodies against the Rift Valley fever virus was successfully developed, with potential for multi-species diagnosis.
Article
Acoustics
Bing Han, Hongli Ji, Li Cheng, Wei Huang, Jinhao Qiu
Summary: This paper reports an unusual splitting phenomenon in a finite plate strip with two-dimensional acoustic black holes (ABHs). The resonance peak that separates the wide attenuation band predicted by a bandgap (BG) splits it into two attenuation bands in the finite strip, challenging the common belief. The study clarifies the underlying mechanism and demonstrates that the splitting can be tuned by disrupting the structural details of the ABH strips.
JOURNAL OF SOUND AND VIBRATION
(2023)
Article
Chemistry, Physical
Hauke Carstensen, Anne Kramer, Vassilios Kapaklis, Max Wolff
Summary: In this study, the self-assembly of branching-chain networks and crystals in a binary colloidal system with tunable interactions was investigated. Particle positions were extracted from microscopy images and order parameters were determined through image processing and statistical analysis. Phase diagrams were constructed based on particle density, ratio, and interaction, and computer simulations were used to complement the experimental results. A region in the phase diagram was identified where symmetric bead ratios and interactions promoted the formation of percolated structures.
Article
Chemistry, Analytical
Hao Liu, Fang Ji, Shou-Nian Ding
Summary: This study presents a carbon black-based immunochromatographic test strip (CB-ICTS) for the detection of SFTSV, which is both quick and easy to operate. The CB-ICTS showed a detection range of 0.1-1000 ng mL(-1) for SFTSV with a limit of detection of 100 pg mL(-1). The study demonstrated the specificity and effectiveness of the CB-ICTS for early detection of SFTSV through evaluating biomarkers and comparing with PCR results.
Article
Thermodynamics
Junfang Ma, Jiaxun Liu, Xiumin Jiang, Hai Zhang
Summary: Pyrolysis kinetic models are crucial for understanding and optimizing various processes. The proposed 2D-DAEM outperforms the classical DAEM in efficiency and accuracy, particularly in analyzing complex reactions like co-pyrolysis. The model is also effective in studying the impact of coal particle size on pyrolysis.
Article
Chemistry, Physical
Dipanjan Mandal, David Quigley
Summary: This study investigates the influence of static and dynamic impurities on droplet free energy and critical nucleus size, finding that increasing static impurity density decreases both the free energy barrier height and critical nucleus size. Nucleation rates obtained from Classical Nucleation Theory and Forward Flux Sampling exhibit good agreement for different static impurity densities. The presence of dynamic impurities results in preferential occupancy at the boundary positions of the nucleus at low temperatures, further enhancing the nucleation rate due to reduced effective interfacial free energy.
Article
Computer Science, Interdisciplinary Applications
Sidong Shen, Lei Wang, Annan Zhou, Yongfu Xu, Xiaohe Xia
Summary: This paper presents a semi-analytical solution for analyzing the consolidation properties of unsaturated soils under a strip-shaped distributed permeable boundary. Through parametric studies and calculation examples under different conditions, the effectiveness and applicability of the preloading consolidation method in ground treatment are investigated.
COMPUTERS AND GEOTECHNICS
(2021)
Article
Engineering, Aerospace
Matteo Di Luca, Kenneth Breuer
Summary: Airfoils operating at low Reynolds numbers suffer from laminar separation, which degrades aerodynamic efficiency. Transition to turbulence improves performance, and experiments have shown that the distance of the shear layer from the wall and the Reynolds number have significant effects on this transition. The transition distance is proportional to the Reynolds number at separation when the shear layer is far from the wall.
Article
Engineering, Aerospace
Matteo Di Luca, Kenneth Breuer, Stefano Mintchev
Summary: In response to the poor aerodynamic power factor of low-Reynolds-number airfoils, a new design strategy combining high airfoil camber and a cavity on the suction side has been proposed to generate a turbulent attached flow, resulting in significant improvements in power factor. Computational analysis and wind-tunnel testing have demonstrated the effectiveness of this design in increasing flight efficiency for small-scale drones.
Article
Engineering, Aerospace
Xiaozhou Fan, Kenneth Breuer
Summary: This study presents a three-dimensional low-order modeling technique for simulating the inertial and aerodynamic forces of animals and robots with flapping heavy and morphing wings. The results show that the two independent models used in this study can accurately predict the thrust/drag balance and lift production. Additionally, the study examines the quantitative effect of wing camber on flight performance.
Article
Biochemical Research Methods
Melissa Mendoza, Mei-Hsiu Chen, Peter Huang, Gretchen J. Mahler
Summary: A three-dimensional microfluidic device was developed to simulate the characteristics of calcific aortic valve disease. The presence of high shear stress and endothelial cells was found to contribute to the formation of calcified nodules.
Article
Mechanics
Varghese Mathai, Asimanshu Das, Kenneth Breuer
Summary: This study tackles the important issue of limiting the spread of the SARS-CoV-2 virus by investigating the potential routes of aerosol transmission inside the passenger cabin of an automobile. The study provides insights into the ventilation effectiveness of different window configurations and proposes strategies for removing airborne contaminants during low-speed driving or in traffic.
Article
Cardiac & Cardiovascular Systems
Sudip Dahal, Jonathan Alejandro Bramsen, Bridget R. Alber, Bruce T. Murray, Peter Huang, Mei-Hsiu Chen, Gretchen J. Mahler
Summary: The study demonstrated a comprehensive model of aortic valve disease, including endothelial cells, interstitial cells, and a stiff and disease-like extracellular matrix. In vitro models of both healthy and diseased valves can help understand the mechanisms of CAVD pathogenesis and serve as a model for testing novel therapeutics.
CARDIOVASCULAR ENGINEERING AND TECHNOLOGY
(2022)
Article
Thermodynamics
Lauren Boston, Peter Huang, Paul R. Chiarot
Summary: Two-phase cooling using electrospray atomization is an efficient method for heat removal from electronic systems. This study focuses on the effects of spray angles on electrospray cooling. The results show that spray angles larger than 30 degrees achieve an evaporation efficiency exceeding 100% at the critical heat flux, while a spray angle of 25 degrees results in 90% efficiency.
APPLIED THERMAL ENGINEERING
(2022)
Article
Cardiac & Cardiovascular Systems
Jonathan Alejandro Bramsen, Bridget R. Alber, Melissa Mendoza, Bruce T. Murray, Mei-Hsiu Chen, Peter Huang, Gretchen J. Mahler
Summary: In this study, a 3D collagen hydrogel co-culture model was created to investigate the role of glycosaminoglycans (GAGs) in the progression of calcific aortic valve disease (CAVD). The results showed that GAGs can affect cell activity, proliferation, and calcific nodule formation. This model has potential applications in improving bioprosthetic valves and testing new treatments for CAVD.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Joseph M. Prisaznuk, Peter Huang, Xin Yong, Paul R. Chiarot
Summary: By using surface energy patterning and electrospray atomization, we created nonspherical droplets and observed the assembly of microparticles at the liquid-air interface. We found that the underlying surface energy pattern played a significant role in the colloidal assembly, driving particles towards the center of the droplet. The particles formed a single, non-close-packed cluster with local hexagonal ordering, but left a clear region with very few particles near the contact line, which was attributed to long-range electrostatic repulsion from the photoresist used to create the surface energy pattern.
Article
Engineering, Mechanical
Zijie Qu, Xiongfeng Yi, Kenneth S. Breuer
Summary: In this study, the viscoelastic behavior of Methocel solutions at various concentrations was measured using a conventional epi-fluorescence microscope coupled to a high-speed intensified camera. Statistical Particle Tracking was used to analyze the mean-squared displacement of the dispersive particles. Relaxation times ranging from 0.76-9.00 ms and viscoelastic moduli, G' between 11.34 and 3.39 were reported for Methocel solutions of concentrations between 0.063-0.5%.
FLOW MEASUREMENT AND INSTRUMENTATION
(2023)
Article
Engineering, Aerospace
Jillian Bohnker, Kenneth Breuer
Summary: This study demonstrates an integrated method for sensing camber and shows its relationship with aerodynamic load and flowfield. Camber is estimated by measuring the capacitance of a dielectric elastomer membrane wing, and a simple aeroelastic analysis captures the mean aerodynamic load well. The ties between dynamic membrane vibration, measured by capacitance, and the behavior of the shear layer above the wing are illustrated using time-resolved membrane kinematics and flowfield measurements. This work is a step toward an integrated, closed-loop control method for membrane wings.
Article
Physics, Multidisciplinary
Varghese Mathai, Asimanshu Das, Dante L. Naylor, Kenneth S. Breuer
Summary: In this study, we investigate the kinematics and dynamics of a flexible membrane disk in a uniform flow. We find that as the flow velocity increases, the membrane deforms into parachute-like shapes and exhibits modified drag behavior. By using experimental measurements and a nonlinear aeroelastic model, we accurately predict the structural response of the membrane and reveal the mechanism by which the membrane oscillations trigger turbulence production in the wake.
PHYSICAL REVIEW LETTERS
(2023)
Article
Multidisciplinary Sciences
Xiaozhou Fan, Sharon Swartz, Kenneth Breuer
Summary: Researchers used a simplified model and simulated flight processes to find that in flying fruit bats, the curvature of the wings is closely related to speed, impacting energy consumption to different degrees, mainly during the downstroke. The model also shows that wing inertia helps balance aerodynamic forces, reducing the muscle power required for weight support and thrust generation.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2022)
Proceedings Paper
Automation & Control Systems
Hamid Vejdani, Xiaozhou Fang, Kenneth Breuer
Summary: This paper studies the robustness of minimally-actuated 3D flapping wing hovering systems under aerodynamic modeling uncertainties. It develops a dynamical model and designs controllers to evaluate and compare the vehicles' robustness under aerodynamic uncertainties. Through simulations, it finds the range of uncertainties that lead to stable responses and provides guidelines for control design.
2022 IEEE/ASME INTERNATIONAL CONFERENCE ON ADVANCED INTELLIGENT MECHATRONICS (AIM)
(2022)
Article
Biology
Jorn A. Cheney, Jeremy C. Rehm, Sharon M. Swartz, Kenneth S. Breuer
Summary: Research on Jamaican fruit bats revealed that the plagiopatagiales proprii muscles in their wing membrane play a role in regulating membrane tension during flight. When these muscles were paralyzed, the bats experienced a decrease in flight speed and were unable to fly at low speeds. Paralysis of these muscles also caused an increase in wing camber, leading to compensatory movements such as increased downstroke angle and wingbeat amplitude.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2022)