Quantitative monitoring of tamoxifen in human plasma extended to 40 metabolites using liquid-chromatography high-resolution mass spectrometry: new investigation capabilities for clinical pharmacology

Addressing MIST (Metabolites in Safety Testing): Bioanalytical Approaches to Address Metabolite Exposures in Humans and Animals

(2013) Hongying Gao et al.   CURRENT DRUG METABOLISM

Reactions and enzymes in the metabolism of drugs and other xenobiotics

(2012) Bernard Testa et al.   DRUG DISCOVERY TODAY

The Generation, Detection, and Effects of Reactive Drug Metabolites

(2012) Andrew V. Stachulski et al.   MEDICINAL RESEARCH REVIEWS

Comparison between a high-resolution single-stage Orbitrap and a triple quadrupole mass spectrometer for quantitative analyses of drugs

(2012) Hugues Henry et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

The emergence of high-resolution MS as the premier analytical tool in the pharmaceutical bioanalysis arena

(2012) Ragu Ramanathan et al.   Bioanalysis

The future key role of LC–high-resolution-MS analyses in clinical laboratories: a focus on quantification

(2012) Bertrand Rochat et al.   Bioanalysis

Quantitative/qualitative analysis using LC–HRMS: the fundamental step forward for clinical laboratories and clinical practice

(2012) Bertrand Rochat   Bioanalysis

Activity Levels of Tamoxifen Metabolites at the Estrogen Receptor and the Impact of Genetic Polymorphisms of Phase I and II Enzymes on Their Concentration Levels in Plasma

(2011) T E Mürdter et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Investigational study of tamoxifen phase I metabolites using chromatographic and spectroscopic analytical techniques

(2011) S.F. Teunissen et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Quantitative and confirmative performance of liquid chromatography coupled to high-resolution mass spectrometry compared to tandem mass spectrometry

(2011) Anton Kaufmann et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Bioanalytical methods for determination of tamoxifen and its phase I metabolites: A review

(2010) S.F. Teunissen et al.   ANALYTICA CHIMICA ACTA

Comprehensive comparison of liquid chromatography selectivity as provided by two types of liquid chromatography detectors (high resolution mass spectrometry and tandem mass spectrometry): “Where is the crossover point?”

(2010) A. Kaufmann et al.   ANALYTICA CHIMICA ACTA

Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development

(2010) F. Peter Guengerich   Drug Metabolism and Pharmacokinetics

An ultra performance liquid chromatography–tandem MS assay for tamoxifen metabolites profiling in plasma: First evidence of 4′-hydroxylated metabolites in breast cancer patients

(2010) E. Dahmane et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The Biochemistry of Drug Metabolism - An Introduction

(2009) Bernard Testa et al.   CHEMISTRY & BIODIVERSITY

The Biochemistry of Drug Metabolism - An Introduction

(2009) Stefanie D. Krämer et al.   CHEMISTRY & BIODIVERSITY

The Biochemistry of Drug Metabolism - An Introduction

(2008) Bernard Testa et al.   CHEMISTRY & BIODIVERSITY

The Biochemistry of Drug Metabolism - An Introduction

(2008) Stefanie D. Krämer et al.   CHEMISTRY & BIODIVERSITY

Imatinib metabolite profiling in parallel to imatinib quantification in plasma of treated patients using liquid chromatography–mass spectrometry

(2008) Bertrand Rochat et al.   JOURNAL OF MASS SPECTROMETRY