Quantitative monitoring of tamoxifen in human plasma extended to 40 metabolites using liquid-chromatography high-resolution mass spectrometry: new investigation capabilities for clinical pharmacology
出版年份 2014 全文链接
标题
Quantitative monitoring of tamoxifen in human plasma extended to 40 metabolites using liquid-chromatography high-resolution mass spectrometry: new investigation capabilities for clinical pharmacology
作者
关键词
Drug metabolites, High-resolution mass spectrometry, Plasma, Quantification, Therapeutic drug monitoring, Triple-quadrupole
出版物
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 406, Issue 11, Pages 2627-2640
出版商
Springer Nature
发表日期
2014-03-18
DOI
10.1007/s00216-014-7682-2
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Addressing MIST (Metabolites in Safety Testing): Bioanalytical Approaches to Address Metabolite Exposures in Humans and Animals
- (2013) Hongying Gao et al. CURRENT DRUG METABOLISM
- Reactions and enzymes in the metabolism of drugs and other xenobiotics
- (2012) Bernard Testa et al. DRUG DISCOVERY TODAY
- The Generation, Detection, and Effects of Reactive Drug Metabolites
- (2012) Andrew V. Stachulski et al. MEDICINAL RESEARCH REVIEWS
- Comparison between a high-resolution single-stage Orbitrap and a triple quadrupole mass spectrometer for quantitative analyses of drugs
- (2012) Hugues Henry et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- The emergence of high-resolution MS as the premier analytical tool in the pharmaceutical bioanalysis arena
- (2012) Ragu Ramanathan et al. Bioanalysis
- The future key role of LC–high-resolution-MS analyses in clinical laboratories: a focus on quantification
- (2012) Bertrand Rochat et al. Bioanalysis
- Quantitative/qualitative analysis using LC–HRMS: the fundamental step forward for clinical laboratories and clinical practice
- (2012) Bertrand Rochat Bioanalysis
- Activity Levels of Tamoxifen Metabolites at the Estrogen Receptor and the Impact of Genetic Polymorphisms of Phase I and II Enzymes on Their Concentration Levels in Plasma
- (2011) T E Mürdter et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Investigational study of tamoxifen phase I metabolites using chromatographic and spectroscopic analytical techniques
- (2011) S.F. Teunissen et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Quantitative and confirmative performance of liquid chromatography coupled to high-resolution mass spectrometry compared to tandem mass spectrometry
- (2011) Anton Kaufmann et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Bioanalytical methods for determination of tamoxifen and its phase I metabolites: A review
- (2010) S.F. Teunissen et al. ANALYTICA CHIMICA ACTA
- Comprehensive comparison of liquid chromatography selectivity as provided by two types of liquid chromatography detectors (high resolution mass spectrometry and tandem mass spectrometry): “Where is the crossover point?”
- (2010) A. Kaufmann et al. ANALYTICA CHIMICA ACTA
- Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development
- (2010) F. Peter Guengerich Drug Metabolism and Pharmacokinetics
- An ultra performance liquid chromatography–tandem MS assay for tamoxifen metabolites profiling in plasma: First evidence of 4′-hydroxylated metabolites in breast cancer patients
- (2010) E. Dahmane et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- The Biochemistry of Drug Metabolism - An Introduction
- (2009) Bernard Testa et al. CHEMISTRY & BIODIVERSITY
- The Biochemistry of Drug Metabolism - An Introduction
- (2009) Stefanie D. Krämer et al. CHEMISTRY & BIODIVERSITY
- The Biochemistry of Drug Metabolism - An Introduction
- (2008) Bernard Testa et al. CHEMISTRY & BIODIVERSITY
- The Biochemistry of Drug Metabolism - An Introduction
- (2008) Stefanie D. Krämer et al. CHEMISTRY & BIODIVERSITY
- Imatinib metabolite profiling in parallel to imatinib quantification in plasma of treated patients using liquid chromatography–mass spectrometry
- (2008) Bertrand Rochat et al. JOURNAL OF MASS SPECTROMETRY
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