On-line electrochemistry–bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors

Electrochemistry in the Mimicry of Oxidative Drug Metabolism by Cytochrome P450s

(2012) Eslam Nouri-Nigjeh et al.   CURRENT DRUG METABOLISM

Development of an online p38α mitogen-activated protein kinase binding assay and integration of LC–HR-MS

(2010) David Falck et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Advances in mass spectrometry-based post-column bioaffinity profiling of mixtures

(2010) Jeroen Kool et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Development of a microfluidic confocal fluorescence detection system for the hyphenation of nano-LC to on-line biochemical assays

(2010) Ferry Heus et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Quantitation of Parent Drug and Its Unstable Metabolites by in Situ Coulometric Oxidation and Liquid Chromatography−Tandem Mass Spectrometry

(2010) Wei Tong et al.   ANALYTICAL CHEMISTRY

Online electrochemistry/mass spectrometry in drug metabolism studies: principles and applications

(2010) Anne Baumann et al.   Expert Opinion on Drug Metabolism & Toxicology

Determination and identification of estrogenic compounds generated with biosynthetic enzymes using hyphenated screening assays, high resolution mass spectrometry and off-line NMR

(2010) Jon S.B. de Vlieger et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Production and on-line acetylcholinesterase bioactivity profiling of chemical and biological degradation products of tacrine

(2010) Lygia Azevedo Marques et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Structural elucidation of biologically active neomycinN-octyl derivatives in a regioisomeric mixture by means of liquid chromatography/ion trap time-of-flight mass spectrometry

(2010) Martin Giera et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Metabolic studies of tetrazepam based on electrochemical simulation in comparison to in vivo and in vitro methods

(2009) Anne Baumann et al.   JOURNAL OF CHROMATOGRAPHY A

Production of a reactive metabolite of troglitazone by electrochemical oxidation performed in nonaqueous medium

(2009) Kayoko Tahara et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Electrochemical parameters and techniques in drug development, with an emphasis on quinones and related compounds

(2008) Elizabeth Anne Hillard et al.   CHEMICAL COMMUNICATIONS

Electrochemical Oxidation of Troglitazone: Identification and Characterization of the Major Reactive Metabolite in Liver Microsomes

(2008) Kim G. Madsen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Use of an Electrochemically Synthesised Metabolite of a Selective Androgen Receptor Modulator for Mass Spectrometry-Based Sports Drug Testing

(2008) Mario Thevis et al.   EUROPEAN JOURNAL OF MASS SPECTROMETRY

SB203580, a pharmacological inhibitor of p38 MAP kinase transduction pathway activates ERK and JNK MAP kinases in primary cultures of human hepatocytes

(2008) Pavla Henklova et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Screening of protein–ligand interactions using dynamic protein-affinity chromatography solid-phase extraction–liquid chromatography–mass spectrometry

(2008) Niels Jonker et al.   JOURNAL OF CHROMATOGRAPHY A