Article
Chemistry, Physical
Montserrat Colilla, Maria Vallet-Regi
Summary: Bacterial antimicrobial resistance is a major threat to global health, and the stalled antibiotic research pipeline has worsened the situation. Nanotechnology offers a potential solution by using nanocarriers to transport and deliver antimicrobials to overcome bacterial resistant barriers. Mesoporous silica nanoparticles (MSNs) have attracted attention due to their unique features. This perspective article outlines recent research in the design and development of organically modified MSNs to fight bacterial infections, addressing the current challenges and future perspectives.
CHEMISTRY OF MATERIALS
(2023)
Article
Chemistry, Physical
Adele R. Latypova, Maxim D. Lebedev, Ilya A. Tarasyuk, Alexander I. Sidorov, Evgeniy V. Rumyantsev, Artur S. Vashurin, Yuriy S. Marfin
Summary: A one-step synthesis method for organomodified silica materials using a special surfactant DDAO was developed in this study, eliminating the need for heat treatment. SEM images revealed that all obtained materials had similar spherical morphology with a particle diameter of about 500 nm. The catalytic activity experiments showed that the amino-modified matrix exhibited the highest activity, while the phenyl-modified matrix demonstrated low activity due to hydrophobic interactions hindering product diffusion.
Article
Chemistry, Analytical
Juan Lu, Zhuo Sun, Xin Zhang, Xiangyu Shan, Qian Wu, Yingjie Zhao, Li Tian
Summary: A novel ECL sensor for glucose detection was developed using Au nanoparticles, Ni metal-organic frameworks nanofibers, and glucose oxidase. The sensor showed a synergistic effect of Ni-MOF NFs and Au NPs, resulting in amplified ECL signals for glucose determination. Ni-MOF NFs were also found to serve as an ECL accelerator for glucose detection. The sensor exhibited high sensitivity and a wide detection range.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Xuexia Liu, Juan Wang, Yinfeng Wang, Chunfang Huang, Zhijun Wang, Limin Liu
Summary: A simple and green colorimetric sensing assay strategy for highly efficient determination of melamine was developed based on the redox reaction of gallic acid with Ag+. Using gallic acid as a reducing and stabilizing agent, monodispersed Ag nanoparticles were obtained. The aggregation of AgNPs, attributed to the formation of hydrogen bonds between melamine and gallic acid, enables rapid detection of melamine concentration with a low detection limit.
Article
Chemistry, Multidisciplinary
Ling Tan, Qing-Yao Li, Yan-Jun Li, Rong-Rong Ma, Jia-Yuan He, Zhuang-Fei Jiang, Li-Li Yang, Chong-Zhi Wang, Ling Luo, Qi-Hui Zhang, Chun-Su Yuan
Summary: In this study, a magnetic molecularly imprinted polymer ZDM-MIPs was synthesized to efficiently adsorb and detect aspartame (ASP) in soft drinks. The use of ZDM-MIPs-MGCE showed a good linear relationship for quantification of ASP concentrations with high accuracy and precision. This method has potential for practical application in determining ASP content in food samples.
Article
Chemistry, Analytical
Alessandra Zanut, Marianna Rossetti, Massimo Marcaccio, Francesco Ricci, Francesco Paolucci, Alessandro Porchetta, Giovanni Valenti
Summary: In this study, we investigated the mechanism of ECL signal generation at the nanoscale using DNA nanoswitches with different stem stabilities. By tuning the stability of the DNA nanoswitches, we were able to activate different ECL mechanisms, achieve a digital-like association curve, and increase signal gain significantly while maintaining low detection limits. Our findings demonstrate the potential for designing customized DNA devices for highly efficient dual-signal-output ratiometric-like ECL systems.
ANALYTICAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Yanna Gurianov, Michael Meistelman, Yael Albo, Marina Nisnevitch, Faina Nakonechny
Summary: This study reports the incorporation of Rose Bengal into organically modified silica matrices using the sol-gel technique. The addition of solidifier to the matrix was found to affect the antibacterial activity of Rose Bengal. The RB6@ORMOSIL matrix immobilized on a linear low-density polyethylene surface exhibited the highest antibacterial activity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Marcos de Oliveira, Kevin Herr, Martin Brodrecht, Nadia B. Haro-Mares, Till Wissel, Vytautas Klimavicius, Hergen Breitzke, Torsten Gutmann, Gerd Buntkowsky
Summary: High-field dynamic nuclear polarization is a powerful tool for structural characterization of species on porous materials or nanoparticles, with radical-containing solutions as the main source of polarization. This study presents a comprehensive strategy for solvent-free DNP enhanced NMR characterization of functional species on the surface of mesoporous silica, achieving DNP enhancements for C-13{H-1} CPMAS signals and Si-29 signals considerably higher than previous approaches, with the cross-effect identified as the dominant polarization transfer mechanism.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Article
Materials Science, Biomaterials
Yasamin Nasiri Khonsari, Shiguo Sun
Summary: A novel MIP-ECL sensor based on CeO2NP/Ru(bpy)(3)(2+)-MIP-chitosan was introduced for ultraselective detection of TRI, showing high sensitivity, selectivity, reproducibility, and stability under optimal conditions. The sensor exhibited linear response in the range of 0.2-100 pM, with a LOD of 0.025 pM, and demonstrated successful analysis of TRI in human serum and urine samples without special pretreatment.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Chemistry, Analytical
Tongtong Zhai, Yuan Xue, Yunhui Li, Jianwei Zhu, Jing Li, Erkang Wang
Summary: In this study, a polystyrene modified glassy carbon electrode was proposed for hot electron-induced electrochemiluminescence (HECL) with a stable and reproducible performance. The HECL mechanism was discussed using ECL spectra and hydrated electron quenchers, and the film was successfully applied in the detection of rutin with a detection limit of 90 nM (S/N = 3) based on the inhibition of SO4 center dot-.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Christina Sarakatsanou, Sophia Karastogianni, Stella Girousi
Summary: In this study, a modified glassy carbon electrode with saffron conjugated silver nanoparticles was developed for the determination of amoxicillin antibiotic in urine samples. The modified electrode showed enhanced electrocatalytic activity and exhibited a linear calibration curve in the concentration range from 1.273 x 10-4 g L-1 to 2.217 x 10-3 g L-1. The method showed potential for the sensitive and selective determination of amoxicillin in urine samples, with a detection limit of 9.739 x 10-6 g L-1.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Christina Sarakatsanou, Sophia Karastogianni, Stella Girousi
Summary: This study developed a modified glassy carbon electrode with saffron conjugated silver nanoparticles to determine amoxicillin antibiotic in urine samples. The modified electrode exhibited enhanced electrocatalytic activity and showed promising results for the sensitive determination of amoxicillin in biological samples.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Yan Jin, Tong Qi, Yuqing Ge, Jin Chen, Lijuan Liang, Jiaqi Ju, Jianlong Zhao
Summary: An ultrasensitive electrochemical determination of phosphate in water was achieved using hydrophilic TiO2 modified glassy carbon electrodes for the first time, with a detection limit of 0.1 μg L-1 and a linear relationship between phosphate concentration and peak current.
ANALYTICAL METHODS
(2021)
Article
Chemistry, Analytical
Ying Gu, Yuanling Hu, Fuyuan Zhang, Lunzhao Yi, Ying Shang, Dabing Ren, Zhenhua Ge
Summary: A glucose sensor was developed using synthetic cyclic peptides as recognition receptors and Au nanoparticles for ECL enhancement. The sensor demonstrated specific glucose capture and detection, with good sensitivity and a low detection limit.
Article
Chemistry, Physical
Saurabh Ailawar, Anagha Hunoor, Yehia Khalifa, Jeffrey T. Miller, Paul L. Edmiston, Umit S. Ozkan
Summary: This study found that ethanol can promote the swelling of SOMS matrix, accelerate the removal of HCl, and alleviate the inhibitory effect of HCl on the hydrodechlorination reaction of TCE.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2021)
Article
Chemistry, Analytical
Mojtaba Shamsipur, Afsaneh Safavi, Zahra Mohammadpour, Raheleh Ahmadi
Article
Chemistry, Multidisciplinary
Afsaneh Safavi, Raheleh Ahmadi, Zahra Mohammadpour, Jie Zhou
Article
Chemistry, Multidisciplinary
Safieh Momeni, Afsaneh Safavi, Raheleh Ahmadi, Iraj Nabipour
Article
Chemistry, Analytical
Afsaneh Safavi, Maryam Mohammadzadeh, Mohsen Sorouri
MICROCHEMICAL JOURNAL
(2017)
Article
Chemistry, Analytical
Afsaneh Safavi, Raheleh Ahmadi, Zahra Mohammadpour
SENSORS AND ACTUATORS B-CHEMICAL
(2017)
Article
Chemistry, Analytical
Safieh Momeni, Raheleh Ahmadi, Afsaneh Safavi, Iraj Nabipour
Review
Biophysics
Alireza Abi, Zahra Mohammadpour, Xiaolei Zuo, Afsaneh Safavi
BIOSENSORS & BIOELECTRONICS
(2018)
Article
Environmental Sciences
Raheleh Ahmadi, Bahram Hemmateenejad, Afsaneh Safavi, Zahra Shojaeifard, Maryam Mohabbati, Omidreza Firuzi
Article
Engineering, Biomedical
Pooya Iranpour, Maral Ajamian, Afsaneh Safavi, Nasser Iranpoor, Abdolkarim Abbaspour, Sanaz Javanmardi
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2018)
Article
Chemistry, Physical
R. Ahmadi, B. Hemmateenejad, A. Safavi, Z. Shojaeifard, A. Shahsavar, A. Mohajeri, M. Heydari Dokoohaki, A. R. Zolghadr
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2018)
Article
Chemistry, Analytical
Afsaneh Safavi, Raheleh Ahmadi, Amir M. Ramezani
MICROCHEMICAL JOURNAL
(2018)
Article
Chemistry, Analytical
Alireza Abi, Ghasem Kazemi, Afsaneh Safavi
SENSORS AND ACTUATORS B-CHEMICAL
(2018)
Article
Chemistry, Analytical
Raheleh Ahmadi, Ghasem Kazemi, Amir M. Ramezani, Afsaneh Safavi
MICROCHEMICAL JOURNAL
(2019)
Article
Chemistry, Physical
Zahra Mohammadpour, Seyyed Hossein Abdollahi, Afsaneh Safavi
ACS APPLIED ENERGY MATERIALS
(2018)
Article
Chemistry, Analytical
Zahra Mohammadpour, Afsaneh Safavi, Seyyed Hossein Abdollahi
ANALYTICA CHIMICA ACTA
(2017)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)