Article
Multidisciplinary Sciences
Sara Y. Chothia, Matthew Carr, Paul S. Monks, Rebecca L. Cordell, Richard J. Hopkinson
Summary: This study reports a novel method for the detection/quantification of formaldehyde (HCHO) using cysteamine-mediated scavenging and SPME GC-MS analysis. The results confirm the efficiency and selectivity of cysteamine as an HCHO scavenger, forming a stable thiazolidine amenable to GC-MS quantification. The method shows sensitivity and chemical robustness for quantifying HCHO in biological samples.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Analytical
Congchao You, Tien Ho, Victor Rucker, Jerry Yeh, Lin Wang
Summary: A simple and universal headspace gas chromatography with flame ionization detection (HS-GC-FID) method is described for accurate quantification of volatile amines in pharmaceuticals. The addition of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) as an additive improves the detectability and method accuracy of residual volatile amines in pharmaceutical products. Method validation shows acceptable linearity, limit of detection, limit of quantitation, solution stability, precision, and robustness.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Applied
Juliana Milheiro, Fernanda Cosme, Luis Filipe-Ribeiro, Fernando M. Nunes
Summary: A simple, fast, and robust method was developed for determining pyruvic acid, acetaldehyde, and alpha-ketobutyric acid in Port wines, dry table wines, and wine spirits. The method involves reductive amination of aldehyde 2,4-dinitrophenylhydrazones using cyanoborohydride followed by HPLC-DAD analysis. The method showed good performance in several parameters and enables simultaneous quantification of these carbonyl compounds in Port wines for the first time.
Article
Chemistry, Analytical
Samin Fathalinejad, Esben Taarning, Peter Christensen, Jan H. Christensen
Summary: This study developed a GC-MS identification workflow for carbohydrate fragmentation compounds, built a library of compounds detected by five different GC-MS methods, investigated and compared compound coverage among the methods, and explored possible reaction pathways for some analytes. A total of 389 compounds were detected, with solid-phase microextraction detecting the highest number of analytes and derivatization GC-MS technique detecting the lowest but largest molecules.
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
(2021)
Article
Chemistry, Analytical
Xiaoqing Tan, Yongpeng Liang, Yingying Ye, Zhihao Liu, Jianxin Meng, Fengyu Li
Summary: This study developed an explainable DL-assisted visualized fluorometric array-based sensing method for efficient qualitative and quantitative analysis of antibiotics. The convolutional neural network achieved high prediction accuracy and guided the improvement of the sensor array through a feedback mechanism.
ANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Hyun-Hee Lim, Kyeong-Yun Choi, Ho-Sang Shin
Summary: An optimal derivatization method using 2,2,2-trifluoroethyl hydrazine (TFEH) was established for the simultaneous determination of 35 carbonyl compounds in 53 cigarette products, with formaldehyde being the most prevalent. This method can effectively differentiate between different types of tobacco products.
Article
Chemistry, Analytical
Brittany Widner, Melissa C. Kido Soule, Frank Xavier Ferrer-Gonzalez, Mary Ann Moran, Elizabeth B. Kujawinski
Summary: Utilizing pre-extraction derivatization and ultrahigh performance liquid chromatography electrospray ionization tandem mass spectrometry, targeted dissolved metabolites in seawater and saline culture media were successfully detected and quantified. This quantitative method has been optimized for 73 common metabolites, with 50 requiring derivatization for quantification due to low extraction efficiencies.
ANALYTICAL CHEMISTRY
(2021)
Article
Meteorology & Atmospheric Sciences
Zhiheng Wang, Xiu Chen, Yongmei Liang, Quan Shi
Summary: This study developed a new analytical method to characterize carbonyl compounds in PM2.5. Thousands of carbonyl formulas were identified, including aliphatic carbonyls and aromatic carbonyls. Carbonyl compounds had the highest contribution to organic matter and PM2.5 in winter, and their concentration showed significant seasonal variation.
ATMOSPHERIC RESEARCH
(2022)
Article
Chemistry, Analytical
Hakan Alyuruk, Aynur Kontas, Oya Altay
Summary: Two reversed-phase HPLC methods were compared for molecular analysis of dissolved free monosaccharides in seawater, with the 2-amino benzamide method showing better results. A total of 12 monosaccharides could be quantified with detection limits between 1.2 and 11 nM and good repeatability. Additional studies using different column polarities may lead to even higher sensitivity and detection of more monosaccharides.
Article
Chemistry, Analytical
Congchao You, Tien Ho, Victor Rucker, Jerry Yeh, Lin Wang
Summary: Volatile amines play a crucial role in pharmaceutical manufacturing for chemical reactions and product optimization. Monitoring and controlling the residual volatile amines in pharmaceutical products is essential for regulatory compliance. This study presents a simple and universal HS-GC-FID method that effectively separates 14 commonly used volatile amines by mitigating chemical reactions with the sample matrix using DBU as an additive.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Jing He, Wei Mao, Wenhui Chen, Wei Shen, Qiaolian Duan, Hai-Wei Shi, Li Tan, Jingyu Kuang, Hian Kee Lee, Sheng Tang
Summary: In this study, a 3D-printed microdevice was designed to fix the extractant for the sensitive detection of histamine using a fluorescence sensing method. This method solves the issue of unstable drop volumes and can be successfully applied to detect histamine in milk.
ANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Analytical
Justyna Piechocka, Rafal Glowacki
Summary: This overview summarizes all documented analytical methods for the quantification of homocysteine thiolactone (HTL) in biological samples, with a focus on pre-analytical treatment strategies and separation techniques. The review also discusses the advantages, pitfalls, and limitations of the methods, as well as the origin and main metabolites of HTL, and the association between civilization diseases and sulfur-containing compounds' metabolism disorders.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Mousa Amayreh, Chanbasha Basheer, Abdi Hassan
Summary: An electrical conductive cloth-assisted electromediated extraction method was developed to preconcentrate biogenic amines in beverage samples. The method showed low detection limits and good calibrations, and it was fast, sensitive, inexpensive and effective.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2023)
Review
Chemistry, Analytical
Tianning Chen, Shuqi Liang, Yuemei Chen, Jiajia Han, Shanyue Guan, Xiaohong Chen, Wei Li, Junlang Qiu, Xin Yang, Fang Zhu, Gangfeng Ouyang
Summary: In recent years, the issue of odor in drinking water caused by disinfection has gained global attention. Accurate quantitative analysis is crucial for controlling and mitigating odorous substances in drinking water. This review summarizes the sampling, sample pretreatment, and analytical detection techniques, particularly quantitative analysis, for residual disinfectants and odorous disinfection byproducts (DBPs), and discusses research advancements and future perspectives in this field.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Qiao-Lian Duan, Hai-Wei Shi, Li Tan, Zhen Liu, Qing Huang, Wei Shen, Ling Cao, Hian Kee Lee, Sheng Tang
Summary: A new ultrahigh-performance supercritical fluid chromatography (UHPSFC) method was developed to solve the difficult separation problem of various biogenic amines (BAs) in gentamicin. The method achieved complete separation of 10 BAs using dansyl chloride derivatization and UHPSFC system. It demonstrated high sensitivity and accuracy, and met the quantification limits required for impurity determination.
ANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Archana Jain, Manju Gupta, Krishna K. Verma
JOURNAL OF CHROMATOGRAPHY A
(2015)
Review
Chemistry, Analytical
Archana Jain, Krishna K. Verma
ANALYTICA CHIMICA ACTA
(2011)
Article
Chemistry, Analytical
Archana Jain, Kishan Reddy-Noone, Aradhana K. K. V. Pillai, Krishna K. Verma
ANALYTICA CHIMICA ACTA
(2013)
Article
Chemistry, Applied
Manju Gupta, Aradhana K. K. V. Pillai, Amrita Singh, Archana Jain, Krishna K. Verma
Article
Biochemical Research Methods
Archana Jain, Soumitra Soni, Krishna K. Verma
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
(2015)
Article
Chemistry, Analytical
Nisha Sharma, Archana Jain, Vandana Kumari Singh, Krishna K. Verma
Review
Chemistry, Analytical
Archana Jain, Krishna K. Verma
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2018)
Article
Chemistry, Applied
Archana Jain, Soumitra Soni, Krishna K. Verma
Summary: The Berthelot reaction for ammonia was studied with the aim of miniaturization and addressing interferences in food and water samples. Various microextraction techniques and colorimetric determination were used to achieve selectivity and high sensitivity in complex matrices for ammonia detection.
Article
Chemistry, Analytical
Archana Jain, Soumitra Soni, Kishan Reddy-Noone, Aradhana K. K. V. Pillai, Krishna K. Verma
ANALYTICAL METHODS
(2017)
Article
Chemistry, Analytical
Krishna K. Verma
ANALYTICAL CHEMISTRY
(2017)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)
