Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 109, Issue -, Pages 62-82Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2018.10.001
Keywords
Biogenic amines; Sample preparation; Derivatization; Applications to real samples; High performance liquid chromatography
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Funding
- Department of Science and Technology, Government of India, New Delhi [SR/WOS-B/658/2016]
- University Grants Commission, New Delhi [F.6-6/2012-13/EMERITUS-2012-13-GEN-866/(SA-II)]
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Covering the literature from 2011 until recently, this review highlights the analytical strategies that have been adopted for the extraction and analysis by high performance liquid chromatography comprising without or with derivatization of biogenic amines in real samples of food and beverages. The alternative ways of detection by tandem mass spectrometry, potential of multiple reaction monitoring and extracted ion chromatograms have been utilized when analyses performed without any derivatization. The reagents employed for derivatization differ widely in their structures, involve a variety of reaction mechanism, and allow detection by UV-absorption, fluorescence or mass spectrometry. The development of such a large number of reagents for a single class of analytes demonstrates the continued endeavours to overcome the implicit difficulties associated with low molar mass and polar analytes in complex sample matrices, and the inherent importance of the analysis of biogenic amines. The discussion presented will allow the alternative techniques to be adopted for particular biogenic amines samples, and have better control over selectivity and sensitivity of the method. (c) 2018 Elsevier B.V. All rights reserved.
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