Interleukin-1 signaling pathway as a therapeutic target in transthyretin amyloidosis

Doxycycline plus tauroursodeoxycholic acid for transthyretin amyloidosis: a phase II study

(2012) Laura Obici et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Dietary curcumin counteracts extracellular transthyretin deposition: Insights on the mechanism of amyloid inhibition

(2012) Nelson Ferreira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neuroinflamm-Aging and Neurodegenerative Diseases: An Overview

(2012) Vincenzo Pizza et al.   CNS & Neurological Disorders-Drug Targets

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Epigallocatechin-3-Gallate as a Potential Therapeutic Drug for TTR-Related Amyloidosis: “In Vivo” Evidence from FAP Mice Models

(2012) Nelson Ferreira et al.   PLoS One

Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade

(2012) C. E. Bulawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A clinical perspective of IL-1β as the gatekeeper of inflammation

(2011) Charles A. Dinarello   EUROPEAN JOURNAL OF IMMUNOLOGY

Chronic inhibition of endoplasmic reticulum stress and inflammation prevents ischaemia-induced vascular pathology in type II diabetic mice

(2011) Ali Amin et al.   JOURNAL OF PATHOLOGY

Interleukin-1 receptor antagonist reduced apoptosis and attenuated intestinal mucositis in a 5-fluorouracil chemotherapy model in mice

(2010) Zhen-Qian Wu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models

(2010) Isabel Cardoso et al.   Journal of Translational Medicine

IL-1 pathways in inflammation and human diseases

(2010) Cem Gabay et al.   Nature Reviews Rheumatology

The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus

(2009) Jeroen J.M. Hoozemans et al.   AMERICAN JOURNAL OF PATHOLOGY

IL-1β receptor blockade protects islets against pro-inflammatory cytokine induced necrosis and apoptosis

(2009) Alice Schwarznau et al.   JOURNAL OF CELLULAR PHYSIOLOGY

IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat

(2009) J. A. Ehses et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of Familial Amyloidotic Polyneuropathy

(2008) Bárbara Macedo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Anakinra in Experimental Acute Myocardial Infarction—Does Dosage or Duration of Treatment Matter?

(2008) Fadi N. Salloum et al.   CARDIOVASCULAR DRUGS AND THERAPY

Anakinra, a Recombinant Human Interleukin-1 Receptor Antagonist, Inhibits Apoptosis in Experimental Acute Myocardial Infarction

(2008) Antonio Abbate et al.   CIRCULATION

The heat shock response modulates transthyretin deposition in the peripheral and autonomic nervous systems

(2008) Sofia Duque Santos et al.   NEUROBIOLOGY OF AGING

Administration of interleukin-1 receptor antagonist ameliorates renal ischemia-reperfusion injury

(2008) Krisztina Rusai et al.   TRANSPLANT INTERNATIONAL