Evaluation of 99mTc-ZIGF1R:4551-GGGC affibody molecule, a new probe for imaging of insulin-like growth factor type 1 receptor expression

Imaging of Platelet-Derived Growth Factor Receptor   Expression in Glioblastoma Xenografts Using Affibody Molecule 111In-DOTA-Z09591

(2014) V. Tolmachev et al.   JOURNAL OF NUCLEAR MEDICINE

Co-inhibition of epidermal growth factor receptor and insulin-like growth factor receptor 1 enhances radiosensitivity in human breast cancer cells

(2013) Ping Li et al.   BMC CANCER

The strength of small: Improved targeting of Insulin-like Growth Factor-1 Receptor (IGF-1R) with F(ab′)2-R1507 fragments in Ewing sarcomas

(2013) Emmy D.G. Fleuren et al.   EUROPEAN JOURNAL OF CANCER

The type 1 insulin-like growth factor receptor signalling system and targeted tyrosine kinase inhibition in cancer

(2013) Minoru Haisa   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

HAHAHA, HEHEHE, HIHIHI, or HKHKHK: Influence of Position and Composition of Histidine Containing Tags on Biodistribution of [99mTc(CO)3]+-Labeled Affibody Molecules

(2013) Camilla Hofström et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Insulin Receptor/Insulin-Like Growth Factor Receptor Family as a Therapeutic Target in Oncology

(2012) M. Pollak   CLINICAL CANCER RESEARCH

Targeting insulin-like growth factor in breast cancer therapeutics

(2012) Michalis V. Karamouzis et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Liver uptake of radiolabeled targeting proteins and peptides: considerations for targeting peptide conjugate design

(2012) Seyed Jalal Hosseinimehr et al.   DRUG DISCOVERY TODAY

[99mTc(CO)3]+-(HE)3-ZIGF1R:4551, a new Affibody conjugate for visualization of insulin-like growth factor-1 receptor expression in malignant tumours

(2012) Anna Orlova et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Tumor Targeting Using Affibody Molecules: Interplay of Affinity, Target Expression Level, and Binding Site Composition

(2012) V. Tolmachev et al.   JOURNAL OF NUCLEAR MEDICINE

Depletion of the type 1 IGF receptor delays repair of radiation-induced DNA double strand breaks

(2012) Benjamin W. Turney et al.   RADIOTHERAPY AND ONCOLOGY

Evaluation of a HER2-targeting affibody molecule combining an N-terminal HEHEHE-tag with a GGGC chelator for 99mTc-labelling at the C terminus

(2012) Hanna Lindberg et al.   TUMOR BIOLOGY

Predicting IGF-1R Therapy Response in Bone Sarcomas: Immuno-SPECT Imaging with Radiolabeled R1507

(2011) E. D. G. Fleuren et al.   CLINICAL CANCER RESEARCH

Use of a HEHEHE Purification Tag Instead of a Hexahistidine Tag Improves Biodistribution of Affibody Molecules Site-Specifically Labeled with99mTc,111In, and125I

(2011) Camilla Hofström et al.   JOURNAL OF MEDICINAL CHEMISTRY

Imaging of Insulinlike Growth Factor Type 1 Receptor in Prostate Cancer Xenografts Using the Affibody Molecule 111In-DOTA-ZIGF1R:4551

(2011) V. Tolmachev et al.   JOURNAL OF NUCLEAR MEDICINE

Molecular Design and Optimization of 99mTc-Labeled Recombinant Affibody Molecules Improves Their Biodistribution and Imaging Properties

(2011) H. Wallberg et al.   JOURNAL OF NUCLEAR MEDICINE

Comparing the Epidermal Growth Factor Interaction with Four Different Cell Lines: Intriguing Effects Imply Strong Dependency of Cellular Context

(2011) Hanna Björkelund et al.   PLoS One

The insulin-like growth factor-I receptor as an oncogene

(2011) Haim Werner et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

HEHEHE-Tagged Affibody Molecule May Be Purified by IMAC, Is Conveniently Labeled with [99mTc(CO)3]+, and Shows Improved Biodistribution with Reduced Hepatic Radioactivity Accumulation

(2010) Vladimir Tolmachev et al.   BIOCONJUGATE CHEMISTRY

Radionuclide Molecular Imaging Using Affibody Molecules

(2010) Sara Ahlgren et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Affibody molecules: Engineered proteins for therapeutic, diagnostic and biotechnological applications

(2010) J. Löfblom et al.   FEBS LETTERS

ImmunoSPECT and ImmunoPET of IGF-1R Expression with the Radiolabeled Antibody R1507 in a Triple-Negative Breast Cancer Model

(2010) S. Heskamp et al.   JOURNAL OF NUCLEAR MEDICINE

Radiolabelled receptor-tyrosine-kinase targeting drugs for patient stratification and monitoring of therapy response: prospects and pitfalls

(2010) Vladimir Tolmachev et al.   LANCET ONCOLOGY

Kit formulation for 99mTc-labeling of recombinant anti-HER2 Affibody molecules with a C-terminally engineered cysteine

(2010) Sara Ahlgren et al.   NUCLEAR MEDICINE AND BIOLOGY

Affibody Molecules for Epidermal Growth Factor Receptor Targeting In Vivo: Aspects of Dimerization and Labeling Chemistry

(2009) V. Tolmachev et al.   JOURNAL OF NUCLEAR MEDICINE

Targeting of HER2-Expressing Tumors with a Site-Specifically 99mTc-Labeled Recombinant Affibody Molecule, ZHER2:2395, with C-Terminally Engineered Cysteine

(2009) S. Ahlgren et al.   JOURNAL OF NUCLEAR MEDICINE

Predictive biomarkers for targeting insulin-like growth factor-I (IGF-I) receptor

(2009) C. P. Carden et al.   MOLECULAR CANCER THERAPEUTICS

The Type 1 Insulin-Like Growth Factor Receptor Pathway

(2008) M. M. Chitnis et al.   CLINICAL CANCER RESEARCH

The insulin receptor substrate-1: A biomarker for cancer?

(2008) Renato Baserga   EXPERIMENTAL CELL RESEARCH

Alternative binding proteins: Affibody binding proteins developed from a small three-helix bundle scaffold

(2008) Per-Åke Nygren   FEBS Journal

Evaluation of Maleimide Derivative of DOTA for Site-Specific Labeling of Recombinant Affibody Molecules

(2007) Sara Ahlgren et al.   BIOCONJUGATE CHEMISTRY