The type 1 insulin-like growth factor receptor signalling system and targeted tyrosine kinase inhibition in cancer

Differential Roles of Insulin-like Growth Factor Receptor- and Insulin Receptor-mediated Signaling in the Phenotypes of Hepatocellular Carcinoma Cells

(2015) Ya-Wen Chen et al.   NEOPLASIA

Expression of IGF-1R in Colorectal Polyps and its Role in Colorectal Carcinogenesis

(2014) H-B. Shan et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

Prognostic associations of insulin-like growth factor-1 receptor in primary uveal melanoma

(2013) Rana'a T. Al-Jamal et al.   CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE

Targeting the insulin-like growth factor 1 receptor (IGF1R) signaling pathway for cancer therapy

(2012) Cristina E Tognon et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Targeting the Insulin Growth Factor Receptor 1

(2012) Fernanda I. Arnaldez et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Efficacy of anti-insulin-like growth factor I receptor monoclonal antibody cixutumumab in mesothelioma is highly correlated with insulin growth factor-I receptor sites/cell

(2012) Neetu Kalra et al.   INTERNATIONAL JOURNAL OF CANCER

Human Monoclonal Antibodies Targeting Nonoverlapping Epitopes on Insulin-like Growth Factor II as a Novel Type of Candidate Cancer Therapeutics

(2012) W. Chen et al.   MOLECULAR CANCER THERAPEUTICS

Receptor Tyrosine Kinases and Targeted Cancer Therapeutics

(2011) Kenji Takeuchi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Targeting the insulin-like growth factor network in cancer therapy

(2011) Isabel Heidegger et al.   CANCER BIOLOGY & THERAPY

Gene Expression Profiling in Multiple Myeloma--Reporting of Entities, Risk, and Targets in Clinical Routine

(2011) T. Meissner et al.   CLINICAL CANCER RESEARCH

Enhanced Efficacy of IGF1R Inhibition in Pediatric Glioblastoma by Combinatorial Targeting of PDGFR / 

(2011) A. Bielen et al.   MOLECULAR CANCER THERAPEUTICS

Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma

(2011) S. Yin et al.   NEURO-ONCOLOGY

Expression of IGF1R in normal breast tissue and subsequent risk of breast cancer

(2010) Rulla M. Tamimi et al.   BREAST CANCER RESEARCH AND TREATMENT

The Insulin-like Growth Factor Signaling Pathway as a Target for Treatment of Colorectal Carcinoma

(2010) Gideon P. Ewing et al.   Clinical Colorectal Cancer

The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis

(2010) Sebastio Perrini et al.   JOURNAL OF ENDOCRINOLOGY

Sex Steroids Upregulate the IGF-1R in Prostate Cancer Cells through a Nongenotropic Pathway

(2009) Giuseppe Pandini et al.   Annals of the New York Academy of Sciences

Cardiac insulin-like growth factor-1 and cyclins gene expression in canine models of ischemic or overpacing cardiomyopathy

(2009) Maryam Mahmoudabady et al.   BMC Cardiovascular Disorders

Structural Basis of Human p70 Ribosomal S6 Kinase-1 Regulation by Activation Loop Phosphorylation

(2009) Tomoko Sunami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin, insulin-like growth factors and neoplasia

(2008) Michael Pollak   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

The insulin-like growth factor-I receptor inhibitor NVP-AEW541 provokes cell cycle arrest and apoptosis in multiple myeloma cells

(2008) Patricia Maiso et al.   BRITISH JOURNAL OF HAEMATOLOGY

Insulin-Like Growth Factor Binding Protein-2 Is a Novel Therapeutic Target Associated with Breast Cancer

(2008) A. I. So et al.   CLINICAL CANCER RESEARCH

Inhibition of insulin-like growth factor-I receptor (IGF-IR) using NVP-AEW541, a small molecule kinase inhibitor, reduces orthotopic pancreatic cancer growth and angiogenesis

(2008) Christian Moser et al.   EUROPEAN JOURNAL OF CANCER

IGF Binding Proteins (IGFBPs) and Regulation of Breast Cancer Biology

(2008) Claire M. Perks et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma

(2008) N Friedrichs et al.   JOURNAL OF PATHOLOGY

Early drug development of inhibitors of the insulin-like growth factor-I receptor pathway: Lessons from the first clinical trials

(2008) J. Rodon et al.   MOLECULAR CANCER THERAPEUTICS

Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas

(2008) Wenhua Piao et al.   MOLECULAR CANCER THERAPEUTICS

Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors

(2008) C. Tarn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA