Chromatin remodeling by polyamines and polyamine analogs

Spermidine inhibits MMP-2 via modulation of histone acetyltransferase and histone deacetylase in HDFs

(2012) In-Hwan Park et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The Role of Methylation in the Intrinsic Dynamics of B- and Z-DNA

(2012) Nuri A. Temiz et al.   PLoS One

Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells

(2011) Qingsong Zhu et al.   AMINO ACIDS

Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes

(2011) Yu Wu et al.   BIOCHEMICAL JOURNAL

Autoimmune Diseases and Polyamines

(2011) Wesley H. Brooks   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Chromatin states in pluripotent, differentiated, and reprogrammed cells

(2011) Cynthia L Fisher et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Influence of Histone Tails and H4 Tail Acetylations on Nucleosome–Nucleosome Interactions

(2011) Ying Liu et al.   JOURNAL OF MOLECULAR BIOLOGY

Polyamine-based small molecule epigenetic modulators

(2011) Shiv K. Sharma et al.   MedChemComm

Spermidinyl-CoA-based HAT inhibitors block DNA repair and provide cancer- specific chemo-and radiosensitization

(2010) Keya Bandyopadhyay et al.   CELL CYCLE

The Role of HDAC6 in Cancer

(2010) Grace I. Aldana-Masangkay et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

(Bis)urea and (Bis)thiourea Inhibitors of Lysine-Specific Demethylase 1 as Epigenetic Modulators

(2010) Shiv K. Sharma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Overexpression of ornithine decarboxylase increases myogenic potential of H9c2 rat myoblasts

(2009) Marco Govoni et al.   AMINO ACIDS

The polyamine transport system as a target for anticancer drug development

(2009) Andrew J. Palmer et al.   AMINO ACIDS

Integration Host Factor (IHF) Dictates the Structure of Polyamine-DNA Condensates: Implications for the Role of IHF in the Compaction of Bacterial Chromatin†

(2009) Tumpa Sarkar et al.   BIOCHEMISTRY

DNA Condensation by Chiral α-Methylated Polyamine Analogues and Protection of Cellular DNA from Oxidative Damage

(2009) Irina Nayvelt et al.   BIOMACROMOLECULES

Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 and Induce Reexpression of Epigenetically Silenced Genes

(2009) Y. Huang et al.   CLINICAL CANCER RESEARCH

Design of polyamine-based therapeutic agents: new targets and new directions

(2009) M.D. Thulani Senanayake et al.   Essays in Biochemistry

Polyamine biosynthesis impacts cellular folate requirements necessary to maintain S-adenosylmethionine and nucleotide pools

(2009) G. Bistulfi et al.   FASEB JOURNAL

Modulation of cellular function by polyamines

(2009) Kazuei Igarashi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Recent Advances in the Development of Polyamine Analogues as Antitumor Agents§

(2009) Robert A. Casero et al.   JOURNAL OF MEDICINAL CHEMISTRY

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Genetics and epigenetics: stability and plasticity during cellular differentiation

(2009) Fabio Mohn et al.   TRENDS IN GENETICS

Difluoromethylornithine stimulates early cardiac commitment of mesenchymal stem cells in a model of mixed culture with cardiomyocytes

(2008) Claudio Muscari et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Polyaminohydroxamic Acids and Polyaminobenzamides as Isoform Selective Histone Deacetylase Inhibitors§

(2008) Sheeba Varghese et al.   JOURNAL OF MEDICINAL CHEMISTRY

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE

Polyamines stabilize left-handed Z-DNA: Using X-ray crystallographic analysis, we have found a new type of polyamine (PA) that stabilizes left-handed Z-DNA

(2007) Hirofumi Ohishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS