The designer leptin antagonist peptide Allo-aca compensates for short serum half-life with very tight binding to the receptor
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The designer leptin antagonist peptide Allo-aca compensates for short serum half-life with very tight binding to the receptor
Authors
Keywords
Anti-proliferation, Dissociation constant, Metabolic stability, Peptide therapeutics, Receptor activation
Journal
AMINO ACIDS
Volume 46, Issue 4, Pages 873-882
Publisher
Springer Nature
Online
2013-12-23
DOI
10.1007/s00726-013-1650-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Leptin and ghrelin prevent hippocampal dysfunction induced by Aβ oligomers
- (2013) I. Martins et al. NEUROSCIENCE
- Designer peptide antagonist of the leptin receptor with peripheral antineoplastic activity
- (2013) Serena Beccari et al. PEPTIDES
- Exploring Leptin Antagonism in Ophthalmic Cell Models
- (2013) Laura Scolaro et al. PLoS One
- The 1,2,4-triazole as a scaffold for the design of ghrelin receptor ligands: development of JMV 2959, a potent antagonist
- (2012) Aline Moulin et al. AMINO ACIDS
- Therapeutic peptides
- (2012) Fernando Albericio et al. Future Medicinal Chemistry
- Characterization of the Interaction Between Endostatin Short Peptide and VEGF Receptor 3
- (2012) Kyu-Yeon Han et al. PROTEIN AND PEPTIDE LETTERS
- Structure of the Human Obesity Receptor Leptin-Binding Domain Reveals the Mechanism of Leptin Antagonism by a Monoclonal Antibody
- (2012) Byron Carpenter et al. STRUCTURE
- Aberrant expressions of leptin and adiponectin receptor isoforms in chronic myeloid leukemia patients
- (2011) Kamile Ozturk et al. CYTOKINE
- Efficacy of a leptin receptor antagonist peptide in a mouse model of triple-negative breast cancer
- (2011) Laszlo Otvos et al. EUROPEAN JOURNAL OF CANCER
- Targeting the leptin receptor: a potential new mode of treatment for breast cancer
- (2011) Laszlo Otvos et al. Expert Review of Anticancer Therapy
- Toward understanding the role of leptin and leptin receptor antagonism in preclinical models of rheumatoid arthritis
- (2011) Laszlo Otvos et al. PEPTIDES
- Easy Strategy To Protect Antimicrobial Peptides from Fast Degradation in Serum
- (2010) D. Knappe et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Peptide-based leptin receptor antagonists for cancer treatment and appetite regulation
- (2010) Laszlo Otvos et al. BIOPOLYMERS
- Development and Characterization of High Affinity Leptins and Leptin Antagonists
- (2010) Michal Shpilman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolic stability of human parathyroid hormone peptide hPTH (1–34) in rat tissue homogenates: kinetics and products of proteolytic degradation
- (2009) Sha Liao et al. AMINO ACIDS
- Leptin-based glycopeptide induces weight loss and simultaneously restores fertility in animal models
- (2009) I. Kovalszky et al. DIABETES OBESITY & METABOLISM
- Blood Collection Techniques in Exotic Small Mammals
- (2009) Janis Ott Joslin Journal of Exotic Pet Medicine
- Development of a pharmacologically improved peptide agonist of the leptin receptor
- (2008) Laszlo Otvos et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started