Immune Regulation of Human Herpesviruses and Its Implications for Human Transplantation

Human Cytomegalovirus Infection Induces a Rapid and Sustained Change in the Expression of NK Cell Receptors on CD8+ T Cells

(2014) A. van Stijn et al.   JOURNAL OF IMMUNOLOGY

T-cell immunity to Kaposi sarcoma-associated herpesvirus: recognition of primary effusion lymphoma by LANA-specific CD4+ T cells

(2012) S. Sabbah et al.   BLOOD

Effective Treatment of Metastatic Forms of Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma with a Novel Adenovirus-Based Adoptive Immunotherapy

(2012) C. Smith et al.   CANCER RESEARCH

Age-dependent increase of memory B cell response to cytomegalovirus in healthy adults

(2012) Judith H. Aberle et al.   EXPERIMENTAL GERONTOLOGY

Ex vivo functional analysis, expansion and adoptive transfer of cytomegalovirus-specific T-cells in patients with glioblastoma multiforme

(2012) Tania Crough et al.   IMMUNOLOGY AND CELL BIOLOGY

Efficacy Results of a Trial of a Herpes Simplex Vaccine

(2012) Robert B. Belshe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human virus-specific effector-type T cells accumulate in blood but not in lymph nodes

(2011) E. B. M. Remmerswaal et al.   BLOOD

Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function

(2011) B. Foley et al.   BLOOD

Immunology in the Clinic Review Series; focus on host responses: T cell responses to herpes simplex viruses

(2011) K. J. Laing et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Understanding human T-cell-mediated immunoregulation through herpesviruses

(2011) Scott R Burrows et al.   IMMUNOLOGY AND CELL BIOLOGY

Antigen-presenting cells of haematopoietic origin prime cytomegalovirus-specific CD8 T-cells but are not sufficient for driving memory inflation during viral latency

(2011) C. K. Seckert et al.   JOURNAL OF GENERAL VIROLOGY

Infection with cytomegalovirus but not herpes simplex virus induces the accumulation of late-differentiated CD4+ and CD8+ T-cells in humans

(2011) E. Derhovanessian et al.   JOURNAL OF GENERAL VIROLOGY

Phenotype, Function, and Gene Expression Profiles of Programmed Death-1 hi CD8 T Cells in Healthy Human Adults

(2011) Jaikumar Duraiswamy et al.   JOURNAL OF IMMUNOLOGY

Primary Cytomegalovirus Phosphoprotein 65–Specific CD8+ T-Cell Responses and T-bet Levels Predict Immune Control During Early Chronic Infection in Lung Transplant Recipients

(2011) Matthew R. Pipeling et al.   JOURNAL OF INFECTIOUS DISEASES

Viral Interleukin-10 Expressed by Human Cytomegalovirus during the Latent Phase of Infection Modulates Latently Infected Myeloid Cell Differentiation

(2011) S. Avdic et al.   JOURNAL OF VIROLOGY

Polyfunctional T Cells Accumulate in Large Human Cytomegalovirus-Specific T Cell Responses

(2011) R. Lachmann et al.   JOURNAL OF VIROLOGY

Different patterns of peripheral migration by memory CD4+ and CD8+ T cells

(2011) Thomas Gebhardt et al.   NATURE

Human cytomegalovirus microRNA miR-US4-1 inhibits CD8+ T cell responses by targeting the aminopeptidase ERAP1

(2011) Sungchul Kim et al.   NATURE IMMUNOLOGY

Expansion of a unique CD57+NKG2Chi natural killer cell subset during acute human cytomegalovirus infection

(2011) S. Lopez-Verges et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune response of varicella vaccinees to different varicella-zoster virus genotypes

(2011) A. Sauerbrei et al.   VACCINE

Molecular Pathogenesis of EBV Susceptibility in XLP as Revealed by Analysis of Female Carriers with Heterozygous Expression of SAP

(2011) Umaimainthan Palendira et al.   PLOS BIOLOGY

Non-Hematopoietic Cells in Lymph Nodes Drive Memory CD8 T Cell Inflation during Murine Cytomegalovirus Infection

(2011) Nicole Torti et al.   PLoS Pathogens

B Cell Repertoire Analysis Identifies New Antigenic Domains on Glycoprotein B of Human Cytomegalovirus which Are Target of Neutralizing Antibodies

(2011) Sonja Pötzsch et al.   PLoS Pathogens

Allogeneic virus-specific T cells with HLA alloreactivity do not produce GVHD in human subjects

(2010) J. J. Melenhorst et al.   BLOOD

Impaired Epstein-Barr virus-specific CD8+ T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family-positive B-cell targets

(2010) A. D. Hislop et al.   BLOOD

Subsets of CD8 +, CD57+ cells in normal, healthy individuals: correlations with human cytomegalovirus (HCMV) carrier status, phenotypic and functional analyses

(2010) E. C. Y. WANG et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Varicella zoster virus glycoprotein E-specific CD4+ T cells show evidence of recent activation and effector differentiation, consistent with frequent exposure to replicative cycle antigens in healthy immune donors

(2010) G. N. Malavige et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Monofunctional and Polyfunctional CD8+ T Cell Responses to Human Herpesvirus 8 Lytic and Latency Proteins

(2010) L. Lepone et al.   Clinical and Vaccine Immunology

Mechanisms that determine plasma cell lifespan and the duration of humoral immunity

(2010) Ian J. Amanna et al.   IMMUNOLOGICAL REVIEWS

Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation

(2010) Kirsten M.L. Hertoghs et al.   JOURNAL OF CLINICAL INVESTIGATION

Human cytomegalovirus elicits fetal γδ T cell responses in utero

(2010) David Vermijlen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD8+ T-cell recognition of human cytomegalovirus latency-associated determinant pUL138

(2010) S.-K. Tey et al.   JOURNAL OF GENERAL VIROLOGY

Cytomegalovirus Viruria and DNAemia in Healthy Seropositive Women

(2010) Nitin Arora et al.   JOURNAL OF INFECTIOUS DISEASES

International Consensus Guidelines on the Management of Cytomegalovirus in Solid Organ Transplantation

(2010) Camille N. Kotton et al.   TRANSPLANTATION

Herpesviruses and immunity: The art of evasion

(2010) Bryan D. Griffin et al.   VETERINARY MICROBIOLOGY

Adoptive T-Cell Therapy of a Lung Transplanted Patient with Severe CMV Disease and Resistance to Antiviral Therapy

(2009) G. Brestrich et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Successful Immunotherapy of HCMV Disease Using Virus-Specific T Cells Expanded from an Allogeneic Stem Cell Transplant Recipient

(2009) G. R. Hill et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Cell-Mediated Immunity to Predict Cytomegalovirus Disease in High-Risk Solid Organ Transplant Recipients

(2009) D. Kumar et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The Presence of Lytic HSV-1 Transcripts and Clonally Expanded T Cells with a Memory Effector Phenotype in Human Sensory Ganglia

(2009) Tobias Derfuss et al.   Annals of the New York Academy of Sciences

Discerning regulation of cis- and trans-presentation of CD8+ T-cell epitopes by EBV-encoded oncogene LMP-1 through self-aggregation

(2009) C. Smith et al.   BLOOD

Impact of Genetic Polymorphisms in Cytomegalovirus Glycoprotein B on Outcomes in Solid‐Organ Transplant Recipients with Cytomegalovirus Disease

(2009) Oriol Manuel et al.   CLINICAL INFECTIOUS DISEASES

Immunobiology of Human Cytomegalovirus: from Bench to Bedside

(2009) T. Crough et al.   CLINICAL MICROBIOLOGY REVIEWS

Findings and conclusions from CMV hyperimmune globulin treatment trials

(2009) Stuart P. Adler et al.   JOURNAL OF CLINICAL VIROLOGY

Epstein-Barr virus (EBV)–encoded small RNA is released from EBV-infected cells and activates signaling from toll-like receptor 3

(2009) Dai Iwakiri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Common Features of γδ T Cells and CD8+αβ T Cells Responding to Human Cytomegalovirus Infection in Kidney Transplant Recipients

(2009) Lionel Couzi et al.   JOURNAL OF INFECTIOUS DISEASES

Cytomegalovirus Reinfections in Healthy Seroimmune Women

(2009) Shannon A. Ross et al.   JOURNAL OF INFECTIOUS DISEASES

Distinct Profiles of Cytotoxic Granules in Memory CD8 T Cells Correlate with Function, Differentiation Stage, and Antigen Exposure

(2009) A. Harari et al.   JOURNAL OF VIROLOGY

Acquisition of Polyfunctionality by Epstein-Barr Virus-Specific CD8+ T Cells Correlates with Increased Resistance to Galectin-1-Mediated Suppression

(2009) C. Smith et al.   JOURNAL OF VIROLOGY

Isolation of Human Monoclonal Antibodies That Potently Neutralize Human Cytomegalovirus Infection by Targeting Different Epitopes on the gH/gL/UL128-131A Complex

(2009) A. Macagno et al.   JOURNAL OF VIROLOGY

An HLA-A2-Restricted T-Cell Epitope Mapped to the BNLF2a Immune Evasion Protein of Epstein-Barr Virus That Inhibits TAP

(2009) M. J. Bell et al.   JOURNAL OF VIROLOGY

Adaptive immune features of natural killer cells

(2009) Joseph C. Sun et al.   NATURE

Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection

(2009) Luc English et al.   NATURE IMMUNOLOGY

Vaccine Prevention of Maternal Cytomegalovirus Infection

(2009) Robert F. Pass et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Epstein-Barr Virus G-Protein-Coupled Receptor Contributes to Immune Evasion by Targeting MHC Class I Molecules for Degradation

(2009) Jianmin Zuo et al.   PLoS Pathogens

Functional Impairment of Cytomegalovirus Specific CD8 T Cells Predicts High-Level Replication After Renal Transplantation

(2008) F. M. Mattes et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Linking CMV Serostatus to Episodes of CMV Reactivation Following Lung Transplantation by Measuring CMV-Specific CD8+T-Cell Immunity

(2008) G. P. Westall et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Polyfunctional Cytomegalovirus-Specific CD4+ and pp65 CD8+ T Cells Protect Against High-Level Replication After Liver Transplantation

(2008) G. Nebbia et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Long-term expansion of effector/memory V 2-    T cells is a specific blood signature of CMV infection

(2008) V. Pitard et al.   BLOOD

Human cytomegalovirus interferes with signal transducer and activator of transcription (STAT) 2 protein stability and tyrosine phosphorylation

(2008) V. T. K. Le et al.   JOURNAL OF GENERAL VIROLOGY

The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression

(2008) P. K. Chattopadhyay et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Functions of natural killer cells

(2008) Eric Vivier et al.   NATURE IMMUNOLOGY

Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity

(2008) M. Thomas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noncytotoxic Lytic Granule-Mediated CD8+ T Cell Inhibition of HSV-1 Reactivation from Neuronal Latency

(2008) J. E. Knickelbein et al.   SCIENCE

Phenotypic and functional heterogeneity of human memory B cells

(2008) Iñaki Sanz et al.   SEMINARS IN IMMUNOLOGY

Programmed Death–1 Expression in Liver Transplant Recipients as a Prognostic Indicator of Cytomegalovirus Disease

(2007) Corinna La Rosa et al.   JOURNAL OF INFECTIOUS DISEASES