Article
Medicine, General & Internal
Ang Lu, Shih-Hua Lin
Summary: Two sexagenarian males presented with progressive muscle paralysis for hours, diagnosed with thyrotoxic periodic paralysis after ruling out other precipitating factors and drugs. Treatment with K+ supplementation led to full recovery of muscle strength in both patients. Lessons learned to consider TPP as an underlying cause of hypokalemia with paralysis and hypertension in elderly patients.
Article
Medicine, General & Internal
Maria R. Iryaningrum, Ignatius Ivan, Fanny Budiman, Erich Tamio
Summary: Thyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism that can be difficult to diagnose due to similar clinical features with other diseases. However, early identification of TPP is crucial based on weakness presentation and characteristic ECG findings.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Medicine, General & Internal
Mohsin Nazir, Malika Hameed, Rizwana Shehzad
Summary: Thyrotoxic hypokalemic periodic paralysis is a rare but life-threatening complication of hyperthyroidism, typically seen in males but can also occur in females without a prior history of thyroid disease. Diagnosis requires recognition of the diverse etiologies, and treatment involves nonselective beta-blockade and potassium replacement, with cure achievable once euthyroidism is achieved.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Medicine, General & Internal
Sean Ho Yoon, Hassan Raza
Summary: Hypokalemic periodic paralysis is characterized by sudden-onset, recurrent muscle weakness episodes, with thyrotoxic periodic paralysis being a specific subtype that requires cautious potassium repletion.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Medicine, General & Internal
Sanjeev Kharel, Rajeev Ojha, Naresh Parajuli, Shiva Bhattarai, Gaurav Parajulee, Ragesh Karn, Bikram Prasad Gajurel, Reema Rajbhandari, Neeraj Gautam, Ashish Shrestha
Summary: Thyrotoxic periodic paralysis (TPP) is a rare hypokalemic periodic paralysis often misdiagnosed, which presents with recurrent acute limb weakness and has a good treatment outcome if diagnosed early. This case report highlights the importance of considering TPP in cases of limb weakness, particularly in patients with hyperthyroidism.
ANNALS OF MEDICINE AND SURGERY
(2022)
Article
Medicine, General & Internal
Nova B. Mebane, Aisha Khan, Manzoor Bevinal, Erin Davis
Summary: Here we report a case of a young male patient who presented with acute paralysis and was found to have new-onset hyperthyroidism and severe hypokalemia. The symptoms of thyrotoxic periodic paralysis (TPP) were exacerbated by the intake of a high carbohydrate meal as well as a steroid injection within 24 hours of symptom onset.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Medicine, General & Internal
Nidhi Kaeley, Salva M. S. Ameena, S. Silpa, Anand M. Gangdev, Mukund Rajta
Summary: Thyrotoxic periodic paralysis (TPP) is a condition characterized by acute onset of hypokalemia and paralysis caused by hyperthyroidism. Hypokalemia and elevated thyroid hormone levels are important diagnostic clues for acute episodes.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Cardiac & Cardiovascular Systems
Juan Duarte Torres, Alexander Marschall, Cristina Fraile Sanz, Belen Biscotti Rodil, Hugo del Castillo Carnevali, David Marti Sanchez
Summary: Thyrotoxic periodic paralysis is a rare but potentially life-threatening condition characterized by sudden muscle weakness and in exceptional cases, severe hypokalemia leading to serious symptoms like ventricular tachycardia. Early recognition and diagnosis are crucial for preventing cardiovascular complications and improving outcomes.
JOURNAL OF ELECTROCARDIOLOGY
(2021)
Article
Medicine, General & Internal
Rajendra Poudel, Surakshya Baral, Suman Adhikari, Umesh Dhungana, Ashesh Pradhan, Shankar Baral, Kamal Kumal, Surya B. Hamal
Summary: Thyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism characterized by episodes of muscle weakness and hypokalemia. This case report presents a 32-year-old male with sudden onset of weakness in bilateral upper and lower limbs, progressing to complete paralysis. The provisional diagnosis was hypokalemic periodic paralysis, later confirmed as TPP.
ANNALS OF MEDICINE AND SURGERY
(2023)
Article
Medicine, General & Internal
Talia E. Rave, Marina Movshovich
Summary: Hypokalemic thyrotoxic periodic paralysis is a rare complication of hyperthyroidism caused by intracellular shift of potassium due to elevated thyroid hormone. Conservative potassium repletion is recommended to avoid inducing hyperkalemia. Several studies have examined the potential benefits of thyroid hormone in treating bipolar disorder.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Medicine, General & Internal
Colten M. Mabile, Kuroush Nezafati
Summary: Thyrotoxic periodic paralysis (TPP) is a unique cause of hypokalemia associated with active thyrotoxicosis, requiring specific management considerations for early identification and appropriate treatment. Clinical presentation of TPP can overlap with other causes of hypokalemia, such as familial periodic paralysis. Prompt diagnostic testing is essential for accurate diagnosis in patients presenting with paralysis and hypokalemia.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Review
Medicine, General & Internal
Luke He, Veronica Lawrence, Wayne V. Moore, Yun Yan
Summary: Thyrotoxic periodic paralysis (TPP) is rarely seen in children and adolescents, with varied clinical manifestations. It is crucial for clinicians to be aware of this rare and life-threatening condition in order to provide timely intervention.
CLINICAL CASE REPORTS
(2021)
Review
Pediatrics
Maria Carolina Colucci, Marica Fabiana Triolo, Simona Petrucci, Flaminia Pugnaloni, Massimiliano Corsino, Melania Evangelisti, Maria Cecilia D'Asdia, Giovanni Di Nardo, Matteo Garibaldi, Gianluca Terrin, Pasquale Parisi
Summary: Hypokalemic periodic paralysis is a rare genetic disorder characterized by episodes of flaccid weakness. Treatment involves potassium supplementation and avoiding triggers. Patient education is crucial for a benign clinical course.
ITALIAN JOURNAL OF PEDIATRICS
(2022)
Article
Endocrinology & Metabolism
Chin Lin, Chin-Sheng Lin, Ding-Jie Lee, Chia-Cheng Lee, Sy-Jou Chen, Shi-Hung Tsai, Feng-Chih Kuo, Tom Chau, Shih-Hua Lin
Summary: The study demonstrates that the AI-ECG system can reliably identify hypokalemia in patients with paralysis, and combining it with routine blood chemistries provides valuable decision support for the early diagnosis of TPP.
JOURNAL OF THE ENDOCRINE SOCIETY
(2021)
Article
Medicine, General & Internal
Yan-Yu Lin, Yu-Shan Hsieh
Summary: A 41-year-old male patient presented with acute lower limb weakness, severe hypokalemia, and hyperthyroidism. Chronic alcohol abuse may have increased the patient's tolerance to the profound hypokalemia, delaying the manifestation of critical symptoms.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Engineering, Biomedical
Weston J. Smith, Huy Tran, James I. Griffin, Jessica Jones, Vivian P. Vu, Lizanne Nilewski, Nathan Gianneschi, Dmitri Simberg
Editorial Material
Endocrinology & Metabolism
Zahrul Ismadi, Amanda J. Caswell, Huy A. Tran
ENDOCRINE PRACTICE
(2018)
Review
Ophthalmology
Huy D. M. Tran, Yen H. Tran, Tuan D. Tran, Monica Jong, Minas Coroneo, Padmaja Sankaridurg
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
(2018)
Article
Economics
Justin Whetten, David N. van der Goes, Huy Tran, Maurice Moffett, Colin Semper, Howard Yonas
JOURNAL OF MEDICAL ECONOMICS
(2018)
Article
Gastroenterology & Hepatology
Ikuo Hirano, Margaret H. Collins, Yehudith Assouline-Dayan, Larry Evans, Sandeep Gupta, Alain M. Schoepfer, Alex Straumann, Ekaterina Safroneeva, Michael Grimm, Heather Smith, Cindy-ann Tompkins, Amy Woo, Robert Peach, Paul Frohna, Sheila Gujrathi, Darryl N. Penenberg, Caiyan Li, Gregory J. Opiteck, Allan Olson, Richard Aranda, Marc E. Rothenberg, Evan S. Dellon, Fergal Donnellan, Marietta Iacucci, William Paterson, Alain Schoepfer, Pablo Abonia, Kamran Ayub, Allan Coates, Sidney Cohen, Evan Dellon, Taddese Desta, Gary Falk, Steven Fein, Nielsen Fernandez-Becker, David Fleischer, Keith Friedenberg, Fayez Ghishan, Sarah Glover, Gary Goldstein, Vikram Gopal, Craig Gross, Robert Nardi, Subra Kugathasan, Brian Lacy, Jeffery Lewis, Paul Menard-Katcher, Benjamin Mitlyng, Fouad Moawad, Rodney Perez, Kathryn Peterson, Francisco Ramirez, Vonda Reeves-Darby, Ron Schey, Javaid Shad, Michael Vaezi, John Wo, Salam Zakko
Editorial Material
Ophthalmology
Padmaja Sankaridurg, Huy D. M. Tran
Article
Computer Science, Software Engineering
Faiz U. L. Muram, Huy Tran, Uwe Zdun
SCIENCE OF COMPUTER PROGRAMMING
(2019)
Article
Clinical Neurology
Meredith P. Murphy, Joji B. Kuramatsu, Audrey Leasure, Guido J. Falcone, Hooman Kamel, Lauren H. Sansing, Christina Kourkoulis, Kristin Schwab, Jordan J. Elm, M. Edip Gurol, Huy Tran, Steven M. Greenberg, Anand Viswanathan, Christopher D. Anderson, Stefan Schwab, Jonathan Rosand, Fu-Dong Shi, Steven J. Kittner, Fernando D. Testai, Daniel Woo, Carl D. Langefeld, Michael L. James, Sebastian Koch, Hagen B. Huttner, Alessandro Biffi, Kevin N. Sheth
Article
Neurosciences
Huy Tran, Aditya Mittal, Varun Sagi, Kathryn Luk, Aithanh Nguyen, Mihir Gupta, Julia Nguyen, Yann Lamarre, Jianxun Lei, Alonso Guedes, Kalpna Gupta
FRONTIERS IN CELLULAR NEUROSCIENCE
(2019)
Article
Plant Sciences
Kern Hunter, Sachie Kimura, Anne Rokka, Huy Cuong Tran, Masatsugu Toyota, Jyrki P. Kukkonen, Michael Wrzaczek
Review
Biochemical Research Methods
Huy Q. Tran, Rahila Batul, Mrinal Bhave, Aimin Yu
BIOTECHNOLOGY JOURNAL
(2019)
Article
Chemistry, Multidisciplinary
Huy Quang Tran, Mrinal Bhave, Guowang Xu, Chenghua Sun, Aimin Yu
FRONTIERS IN CHEMISTRY
(2019)
Article
Pathology
Alexis Hure, Kerrin Palazzi, Roseanne Peel, David Geraghty, Phillip Collard, Theo De Malmanche, Huy Tran, Penny Reeves, Andrew Searles, Louisa Jorm, John Attia
Article
Oncology
Sandy Tun Min, Ina I. C. Nordman, Huy A. Tran
CASE REPORTS IN ONCOLOGY
(2019)
Review
Ophthalmology
Padmaja Sankaridurg, Fabian Conrad, Huy Tran, Jianfeng Zhu
ASIA-PACIFIC JOURNAL OF OPHTHALMOLOGY
(2018)