Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium

Mast cell-neural interactions contribute to pain and itch

(2018) Kalpna Gupta et al.   IMMUNOLOGICAL REVIEWS

MRI measurements of Blood-Brain Barrier function in dementia: A review of recent studies

(2018) Rajikha Raja et al.   NEUROPHARMACOLOGY

Substance P and IL-33 administered together stimulate a marked secretion of IL-1β from human mast cells, inhibited by methoxyluteolin

(2018) Alexandra Taracanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebral hemodynamic assessment and neuroimaging across the lifespan in sickle cell disease

(2017) Lori C Jordan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease

(2017) Kenneth I. Ataga et al.   NEW ENGLAND JOURNAL OF MEDICINE

SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors

(2017) Alexandra Taracanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substance P and sickle cell disease-a marker for pain and novel therapeutic approaches

(2016) Steven D. Douglas   BRITISH JOURNAL OF HAEMATOLOGY

Substance P is increased in patients with sickle cell disease and associated with haemolysis and hydroxycarbamide use

(2016) Amanda M. Brandow et al.   BRITISH JOURNAL OF HAEMATOLOGY

Quantitative sensory testing and pain-evoked cytokine reactivity

(2016) Claudia M. Campbell et al.   PAIN

Electroacupuncture in conscious free-moving mice reduces pain by ameliorating peripheral and central nociceptive mechanisms

(2016) Ying Wang et al.   Scientific Reports

Multiple Mechanisms of Unfolded Protein Response–Induced Cell Death

(2015) Nobuhiko Hiramatsu et al.   AMERICAN JOURNAL OF PATHOLOGY

The Role of Endoplasmic Reticulum Stress in Human Pathology

(2015) Scott A. Oakes et al.   Annual Review of Pathology-Mechanisms of Disease

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Spinal glial activation and oxidative stress are alleviated by treatment with curcumin or coenzyme Q in sickle mice

(2015) Y. Valverde et al.   HAEMATOLOGICA

Mast Cell-Mediated Mechanisms of Nociception

(2015) Anupam Aich et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sensitization of nociceptive spinal neurons contributes to pain in a transgenic model of sickle cell disease

(2015) Giuseppe Cataldo et al.   PAIN

Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain

(2015) Bora Inceoglu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spinal glial activation and oxidative stress are alleviated by treatment with curcumin or coenzyme Q in sickle mice

(2015) Y. Valverde et al.   HAEMATOLOGICA

Evidence that Meningeal Mast Cells Can Worsen Stroke Pathology in Mice

(2014) Ahmet Arac et al.   AMERICAN JOURNAL OF PATHOLOGY

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction

(2014) Maria Galán et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Sickle cell disease increases high mobility group box 1: a novel mechanism of inflammation

(2014) H. Xu et al.   BLOOD

Induction of fetal hemoglobin through enhanced translation efficiency of  -globin mRNA

(2014) C. K. Hahn et al.   BLOOD

Endoplasmic reticulum stress plays critical role in brain damage after chronic intermittent hypoxia in growing rats

(2014) Xiao-Hong Cai et al.   EXPERIMENTAL NEUROLOGY

Cellular Adhesion and the Endothelium

(2014) Abdullah Kutlar et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Preventive effect of gomisin J from Schisandra chinensis on angiotensin II-induced hypertension via an increased nitric oxide bioavailability

(2014) Byeong Hyeok Ye et al.   HYPERTENSION RESEARCH

Endoplasmic reticulum stress and endothelial dysfunction

(2014) Stefania Lenna et al.   IUBMB LIFE

Evidence That Dendritic Mitochondria Negatively Regulate Dendritic Branching in Pyramidal Neurons in the Neocortex

(2014) T. Kimura et al.   JOURNAL OF NEUROSCIENCE

Endoplasmic Reticulum Stress and Nox-Mediated Reactive Oxygen Species Signaling in the Peripheral Vasculature: Potential Role in Hypertension

(2013) Celio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

HMGB1 induces an inflammatory response in endothelial cells via the RAGE-dependent endoplasmic reticulum stress pathway

(2013) Ying Luo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies

(2013) D. Manwani et al.   BLOOD

Mast cell activation contributes to sickle cell pathobiology and pain in mice

(2013) L. Vincent et al.   BLOOD

The role of histamine in neurogenic inflammation

(2013) A C Rosa et al.   BRITISH JOURNAL OF PHARMACOLOGY

The interaction between oxidative stress and mast cell activation plays a role in acute lung injuries induced by intestinal ischemia–reperfusion

(2013) Weicheng Zhao et al.   JOURNAL OF SURGICAL RESEARCH

Intravital analysis of vascular permeability in mice using two-photon microscopy

(2013) Gyohei Egawa et al.   Scientific Reports

A potent oral P-selectin blocking agent improves microcirculatory blood flow and a marker of endothelial cell injury in patients with sickle cell disease

(2012) Abdullah Kutlar et al.   AMERICAN JOURNAL OF HEMATOLOGY

Rapid Histamine-Induced Neutrophil Recruitment Is Sphingosine Kinase-1 Dependent

(2012) Wai Y. Sun et al.   AMERICAN JOURNAL OF PATHOLOGY

Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction

(2012) Guorui Dou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Salubrinal promotes healing of surgical wounds in rat femurs

(2012) Ping Zhang et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Endoplasmic Reticulum (ER) Stress in Cumulus-Oocyte Complexes Impairs Pentraxin-3 Secretion, Mitochondrial Membrane Potential (ΔΨm), and Embryo Development

(2012) Linda L. Wu et al.   MOLECULAR ENDOCRINOLOGY

The vascular neural network—a new paradigm in stroke pathophysiology

(2012) John H. Zhang et al.   Nature Reviews Neurology

Endoplasmic reticulum stress mediates aristolochic acid I-induced apoptosis in human renal proximal tubular epithelial cells

(2012) Shaohua Zhu et al.   TOXICOLOGY IN VITRO

Oxidative Stress and Blood–Brain Barrier Dysfunction Under Particular Consideration of Matrix Metalloproteinases

(2011) Christine Lehner et al.   ANTIOXIDANTS & REDOX SIGNALING

Biomarkers in sickle cell disease

(2011) David C. Rees et al.   BRITISH JOURNAL OF HAEMATOLOGY

Mouse models for studying pain in sickle disease: effects of strain, age, and acuteness

(2011) David M. Cain et al.   BRITISH JOURNAL OF HAEMATOLOGY

Mast Cells Play a Critical Role in the Systemic Inflammatory Response and End-Organ Injury Resulting from Trauma

(2011) Changchun Cai et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Selective Inhibition of a Regulatory Subunit of Protein Phosphatase 1 Restores Proteostasis

(2011) P. Tsaytler et al.   SCIENCE

Inhibition of cell adhesion by anti-P-selectin aptamer: a new potential therapeutic agent for sickle cell disease

(2010) D. R. Gutsaeva et al.   BLOOD

Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids

(2010) D. R. Kohli et al.   BLOOD

Sickle-cell disease

(2010) David C Rees et al.   LANCET

Molecular mechanisms of endothelial hyperpermeability: implications in inflammation

(2009) Puneet Kumar et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes

(2008) Donalyn Scheuner et al.   ENDOCRINE REVIEWS

Basal Levels of eIF2α Phosphorylation Determine Cellular Antioxidant Status by Regulating ATF4 and xCT Expression

(2008) Jan Lewerenz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DETECTION AND ASSESSMENT OF STROKE IN PATIENTS WITH SICKLE CELL DISEASE: Neuropsychological Functioning and Magnetic Resonance Imaging

(2008) Jeffrey I. Gold et al.   PEDIATRIC HEMATOLOGY AND ONCOLOGY