Targeted Inhibition of KCa3.1 Channel Attenuates Airway Inflammation and Remodeling in Allergic Asthma

Blunted IgE-Mediated Activation of Mast Cells in Mice Lacking the Ca2+-Activated K+ Channel KCa3.1

(2014) E. Shumilina et al.   JOURNAL OF IMMUNOLOGY

Airway Smooth Muscle Hypertrophy and Hyperplasia in Asthma

(2012) Alan L. James et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ca2+-Activated K+Channel–3.1 Blocker TRAM-34 Attenuates Airway Remodeling and Eosinophilia in a Murine Asthma Model

(2012) Pierre-Olivier Girodet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Adoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation

(2012) Andrew Q Ford et al.   BMC IMMUNOLOGY

Regulatory role of antigen-induced interleukin-10, produced by CD4+ T cells, in airway neutrophilia in a murine model for asthma

(2011) Takeshi Nabe et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Functional KCa3.1 K+ channels are required for human fibrocyte migration

(2011) Glenn Cruse et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Intermediate-Conductance Ca2+-Activated K+ Channel, KCa3.1, as a Novel Therapeutic Target for Benign Prostatic Hyperplasia

(2011) S. Ohya et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Role of neutrophils in persistent airway obstruction due to refractory asthma

(2011) JAE-SUNG CHOI et al.   RESPIROLOGY

Exposure to Mycotoxins Increases the Allergic Immune Response in a Murine Asthma Model

(2010) Nicole Schütze et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inhibition of the K+ channel KCa3.1 ameliorates T cell-mediated colitis

(2010) L. Di et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic potential of KCa3.1 blockers: recent advances and promising trends

(2010) Heike Wulff et al.   Expert Review of Clinical Pharmacology

Osteopontin Deficiency Protects against Airway Remodeling and Hyperresponsiveness in Chronic Asthma

(2009) Davina C. M. Simoes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The K+channels KCa3.1 and Kv1.3 as novel targets for asthma therapy

(2009) Peter Bradding et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells

(2008) Hélène Klein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

NFAT1 Transcription Factor Regulates Pulmonary Allergic Inflammation and Airway Responsiveness

(2008) Bruna P. F. Fonseca et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Local Delivery of the K Ca 3.1 Blocker, TRAM-34, Prevents Acute Angioplasty-Induced Coronary Smooth Muscle Phenotypic Modulation and Limits Stenosis

(2008) D.L. Tharp et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia

(2008) K. I. Ataga et al.   BLOOD

The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans

(2008) Kazuyoshi Toyama et al.   JOURNAL OF CLINICAL INVESTIGATION