N-Acetylcysteine Protects Murine Alveolar Type II Cells from Cigarette Smoke Injury in a Nuclear Erythroid 2–Related Factor–2–Independent Manner

Efficient and rapid isolation and purification of mouse alveolar type II epithelial cells

(2012) Elise M. Messier et al.   EXPERIMENTAL LUNG RESEARCH

NLRC4 Inflammasome-Mediated Production of IL-1  Modulates Mucosal Immunity in the Lung against Gram-Negative Bacterial Infection

(2012) S. Cai et al.   JOURNAL OF IMMUNOLOGY

Mitogen- and Stress-Activated Kinase 1 (MSK1) Regulates Cigarette Smoke-Induced Histone Modifications on NF-κB-dependent Genes

(2012) Isaac K. Sundar et al.   PLoS One

Nrf2 protects human alveolar epithelial cells against injury induced by influenza A virus

(2012) Beata Kosmider et al.   RESPIRATORY RESEARCH

Role of Nrf2 in Host Defense against Influenza Virus in Cigarette Smoke-Exposed Mice

(2011) Y. Yageta et al.   JOURNAL OF VIROLOGY

Chronic Obstructive Pulmonary Disease: A Concise Review

(2011) Ron Balkissoon et al.   MEDICAL CLINICS OF NORTH AMERICA

N-Acetylcysteine Increases the Frequency of Bone Marrow Pro-B/Pre-B Cells, but Does Not Reverse Cigarette Smoking-Induced Loss of This Subset

(2011) Victoria L. Palmer et al.   PLoS One

Human Alveolar Epithelial Cell Injury Induced by Cigarette Smoke

(2011) Beata Kosmider et al.   PLoS One

l-NAME and l-arginine differentially ameliorate cigarette smoke-induced emphysema in mice

(2011) Samuel Santos Valença et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

NRF2 targeting: a promising therapeutic strategy in chronic obstructive pulmonary disease

(2011) A. Boutten et al.   TRENDS IN MOLECULAR MEDICINE

Oxidative stress targets in pulmonary emphysema: focus on the Nrf2 pathway

(2010) A Boutten et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Apoptosis induced by ozone and oxysterols in human alveolar epithelial cells

(2010) Beata Kosmider et al.   FREE RADICAL BIOLOGY AND MEDICINE

N-acetylcysteine attenuates phosgene-induced acute lung injury via up-regulation of Nrf2 expression

(2010) Lin Ji et al.   INHALATION TOXICOLOGY

Effect of N-Acetylcysteine on Air Trapping in COPD

(2009) David Stav et al.   CHEST

Nrf2 Enhances Cell Proliferation and Resistance to Anticancer Drugs in Human Lung Cancer

(2009) S. Homma et al.   CLINICAL CANCER RESEARCH

OralN-acetylcysteine attenuates pulmonary emphysema and alveolar septal cell apoptosis in smoking-induced COPD in rats

(2009) Shan CAI et al.   RESPIROLOGY

Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1

(2008) Deepti Malhotra et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Proteomic Analysis in Lung Tissue of Smokers and COPD Patients

(2008) Eun Joo Lee et al.   CHEST

Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

(2008) C.J. Harvey et al.   FREE RADICAL BIOLOGY AND MEDICINE

Alveolar cell apoptosis is dependent on p38 MAP kinase-mediated activation of xanthine oxidoreductase in ventilator-induced lung injury

(2008) Anne Le et al.   JOURNAL OF APPLIED PHYSIOLOGY

Molecular pathogenesis of emphysema

(2008) Laimute Taraseviciene-Stewart et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling

(2008) N M Reddy et al.   ONCOGENE

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

(2008) T. E. Sussan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema

(2008) D Goven et al.   THORAX

Review: Antioxidant therapeutic advances in COPD

(2008) Irfan Rahman   Therapeutic Advances in Respiratory Disease