Lysophosphatidic Acid Receptor–2 Deficiency Confers Protection against Bleomycin-Induced Lung Injury and Fibrosis in Mice

Autotaxin Emerges as a Therapeutic Target for Idiopathic Pulmonary Fibrosis

(2013) Andrew M. Tager   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis

(2013) Long Shuang Huang et al.   FASEB JOURNAL

Activation of TGF-β1 Promoter by Hepatitis C Virus-Induced AP-1 and Sp1: Role of TGF-β1 in Hepatic Stellate Cell Activation and Invasion

(2013) Lance D. Presser et al.   PLoS One

Pulmonary Autotaxin Expression Contributes to the Pathogenesis of Pulmonary Fibrosis

(2012) Nikos Oikonomou et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Molecular Mechanisms in Progressive Idiopathic Pulmonary Fibrosis

(2012) Mark P. Steele et al.   Annual Review of Medicine

Lysophospholipid receptor activation of RhoA and lipid signaling pathways

(2012) Sunny Yang Xiang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Regulation of TGF-β storage and activation in the human idiopathic pulmonary fibrosis lung

(2012) Outi Leppäranta et al.   CELL AND TISSUE RESEARCH

Lysophosphatidic acid activates TGFBIp expression in human corneal fibroblasts through a TGF-β1-dependent pathway

(2012) Eun Su Jeon et al.   CELLULAR SIGNALLING

Novel Role for Non-muscle Myosin Light Chain Kinase (MLCK) in Hyperoxia-induced Recruitment of Cytoskeletal Proteins, NADPH Oxidase Activation, and Reactive Oxygen Species Generation in Lung Endothelium

(2012) Peter V. Usatyuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Lysophosphatidic Acid Receptor LPA1Promotes Epithelial Cell Apoptosis after Lung Injury

(2011) Manuela Funke et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma

(2011) Flavia V. Castelino et al.   ARTHRITIS AND RHEUMATISM

Blockade of lysophosphatidic acid receptors LPAR1/3 ameliorates lung fibrosis induced by irradiation

(2011) Lu Gan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Induction of cellular antioxidant defense by amifostine improves ventilator-induced lung injury*

(2011) Panfeng Fu et al.   CRITICAL CARE MEDICINE

Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition

(2011) Javier Milara et al.   THORAX

Lysophosphatidic acid stimulates epidermal growth factor-family ectodomain shedding and paracrine signaling from human lung fibroblasts

(2011) Tetsuya Shiomi et al.   WOUND REPAIR AND REGENERATION

Prolonged Exposure to Sphingosine 1–Phosphate Receptor-1 Agonists Exacerbates Vascular Leak, Fibrosis, and Mortality after Lung Injury

(2010) Barry S. Shea et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

LPA Receptors: Subtypes and Biological Actions

(2010) Ji Woong Choi et al.   Annual Review of Pharmacology and Toxicology

A novel, orally active LPA1 receptor antagonist inhibits lung fibrosis in the mouse bleomycin model

(2010) JS Swaney et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lysophosphatidylcholine Containing Docosahexaenoic Acid at the sn-1 Position is Anti-inflammatory

(2010) Long Shuang Huang et al.   LIPIDS

Lysophosphatidic Acid Induces αvβ6 Integrin-Mediated TGF-β Activation via the LPA2 Receptor and the Small G Protein Gαq

(2009) Ming Yan Xu et al.   AMERICAN JOURNAL OF PATHOLOGY

Lysophosphatidic acid and renal fibrosis

(2008) J PRADERE   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Two pathways for lysophosphatidic acid production

(2008) J AOKI   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Oxygenation of Arachidonoyl Lysophospholipids by Lipoxygenases from Soybean, Porcine Leukocyte, or Rabbit Reticulocyte

(2008) Long Shuang Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY