ADAM8 in Asthma. Friend or Foe to Airway Inflammation?

Adam8 Limits the Development of Allergic Airway Inflammation in Mice

(2013) M. D. Knolle et al.   JOURNAL OF IMMUNOLOGY

ADAM8 in squamous cell carcinoma of the head and neck: a retrospective study

(2012) Valerie Zielinski et al.   BMC CANCER

Cell Elasticity Determines Macrophage Function

(2012) Naimish R. Patel et al.   PLoS One

Differential effects of extracellular matrix and mechanical strain on airway smooth muscle cells from ovalbumin- vs saline-challenged Brown Norway rats

(2012) Stephanie M. Pasternyk et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Increased Expression of a Disintegrin and Metalloprotease 8 in Allergic Rhinitis

(2011) Il-Ho Park et al.   American Journal of Rhinology & Allergy

The metalloprotease ADAM8 is associated with and regulates the function of the adhesion receptor PSGL-1 through ERM proteins

(2011) Maria Domínguez-Luis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulating inflammation: ADAM8 - a new player in the game

(2011) Alexander Zarbock et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Overexpression of a disintegrin and metalloprotease 8 in human gliomas is implicated in tumor progression and prognosis

(2011) Shiming He et al.   MEDICAL ONCOLOGY

The Metalloprotease-Disintegrin ADAM8 Is Essential for the Development of Experimental Asthma

(2010) Silvia Naus et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Thiol isomerases negatively regulate the cellular shedding activity of ADAM17

(2010) Sofie H. Willems et al.   BIOCHEMICAL JOURNAL

Metalloprotease-Dependent Onset of Blood Circulation in Zebrafish

(2010) Atsuo Iida et al.   CURRENT BIOLOGY

ADAM-8, a metalloproteinase, drives acute allergen-induced airway inflammation

(2010) Geneviève Paulissen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Low Cholesterol Triggers Membrane Microdomain-dependent CD44 Shedding and Suppresses Tumor Cell Migration

(2010) Toshiyuki Murai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site

(2010) S. M. Le Gall et al.   JOURNAL OF CELL SCIENCE

Novel alternatively spliced ADAM8 isoforms contribute to the aggressive bone metastatic phenotype of lung cancer

(2010) I Hernández et al.   ONCOGENE

ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala271

(2009) Marc D. Zack et al.   ARTHRITIS AND RHEUMATISM

Proteolytic interstitial cell migration: a five-step process

(2009) Peter Friedl et al.   CANCER AND METASTASIS REVIEWS

ADAM8/MS2/CD156, an Emerging Drug Target in the Treatment of Inflammatory and Invasive Pathologies

(2009) Garrit Koller et al.   CURRENT PHARMACEUTICAL DESIGN

ADAM12 localizes with c-Src to actin-rich structures at the cell periphery and regulates Src kinase activity

(2009) Dorte Stautz et al.   EXPERIMENTAL CELL RESEARCH

ADAM8: a new therapeutic target for asthma

(2009) Martin D Knolle et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Mouse models of asthma: a comparison between C57BL/6 and BALB/c strains regarding bronchial responsiveness, inflammation, and cytokine production

(2009) Maud M. Gueders et al.   INFLAMMATION RESEARCH

The mechanical integrin cycle

(2009) E. Puklin-Faucher et al.   JOURNAL OF CELL SCIENCE

Upregulation of ADAM8 in the Airways of Mice with Allergic Bronchial Asthma

(2009) Yoshihiko Chiba et al.   LUNG

Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma

(2009) Sangeeta Goswami et al.   NATURE IMMUNOLOGY

Increased serum ADAM8 concentration in patients with drug-induced eosinophilic pneumonia-ADAM8 expression depends on a the allergen route of entry

(2009) Osamu Matsuno et al.   RESPIRATORY MEDICINE

New asthma biomarkers: lessons from murine models of acute and chronic asthma

(2008) Emmanuel Di Valentin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Involvement of a disintegrin and a metalloproteinase 8 (ADAM8) in osteoclastogenesis and pathological bone destruction

(2008) M Ainola et al.   ANNALS OF THE RHEUMATIC DISEASES

Regulated Expression of ADAM8 (a Disintegrin and Metalloprotease Domain 8) in the Mouse Ovary: Evidence for a Regulatory Role of Luteinizing Hormone, Progesterone Receptor, and Epidermal Growth Factor-Like Growth Factors1

(2008) Venkataraman Sriraman et al.   BIOLOGY OF REPRODUCTION

Autoactivation of human ADAM8: a novel pre-processing step is required for catalytic activity

(2008) Troii Hall et al.   BIOSCIENCE REPORTS

TNF-α-induced up-regulation of intercellular adhesion molecule-1 is regulated by a Rac-ROS-dependent cascade in human airway epithelial cells

(2008) Hyunju Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Leukocyte cell surface proteinases: Regulation of expression, functions, and mechanisms of surface localization

(2008) C OWEN   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cellular roles of ADAM12 in health and disease

(2008) Marie Kveiborg et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The cytokine network in asthma and chronic obstructive pulmonary disease

(2008) Peter J. Barnes   JOURNAL OF CLINICAL INVESTIGATION

ADAM8 is selectively up-regulated in endothelial cells and is associated with angiogenesis after spinal cord injury in adult mice

(2008) Edward T. Mahoney et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Tissue and matrix influences on airway smooth muscle function

(2008) Janette K. Burgess et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Airway smooth muscle and bronchospasm: Fluctuating, fluidizing, freezing

(2008) Ramaswamy Krishnan et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY