The a“MAZE”ing World of Lung-Specific Transgenic Mice

Alveolar Epithelial Type II Cells Induce T Cell Tolerance to Specific Antigen

(2014) B. Lo et al.   JOURNAL OF IMMUNOLOGY

Keratin promoter based gene manipulation in the murine conducting airway

(2012) Stephen P. Malkoski et al.   International Journal of Biological Sciences

Epithelial Progenitor Cells in Lung Development, Maintenance, Repair, and Disease

(2011) Jason R. Rock et al.   Annual Review of Cell and Developmental Biology

A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse

(2011) Anna Ferrer-Vaquer et al.   BMC DEVELOPMENTAL BIOLOGY

Cell of Origin of Small Cell Lung Cancer: Inactivation of Trp53 and Rb1 in Distinct Cell Types of Adult Mouse Lung

(2011) Kate D. Sutherland et al.   CANCER CELL

Uncoupling Cancer Mutations Reveals Critical Timing of p53 Loss in Sarcomagenesis

(2011) N. P. Young et al.   CANCER RESEARCH

A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference

(2011) Prem K. Premsrirut et al.   CELL

Notch-Dependent Differentiation of Adult Airway Basal Stem Cells

(2011) Jason R. Rock et al.   Cell Stem Cell

Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development

(2011) Po-Nien Tsao et al.   DEVELOPMENT

HuR controls lung branching morphogenesis and mesenchymal FGF networks

(2011) Nikos Sgantzis et al.   DEVELOPMENTAL BIOLOGY

Quantification of factors influencing fluorescent protein expression using RMCE to generate an allelic series in the ROSA26 locus in mice

(2011) S. X. Chen et al.   Disease Models & Mechanisms

Unsuspected effects of a lung-specific cre deleter mouse line

(2011) Lucie Jeannotte et al.   GENESIS

Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice

(2011) Harold A. Chapman et al.   JOURNAL OF CLINICAL INVESTIGATION

Contrasting Expression of Canonical Wnt Signaling Reporters TOPGAL, BATGAL and Axin2LacZ during Murine Lung Development and Repair

(2011) Denise Al Alam et al.   PLoS One

Tracheal Basal Cells

(2010) Brook B. Cole et al.   AMERICAN JOURNAL OF PATHOLOGY

Can lineage-specific markers be identified to characterize mesenchyme-derived cell populations in the human airways?

(2010) Shailendra R. Singh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Overexpression of Smad2 Drives House Dust Mite–mediated Airway Remodeling and Airway Hyperresponsiveness via Activin and IL-25

(2010) Lisa G. Gregory et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Conditional Depletion of Airway Progenitor Cells Induces Peribronchiolar Fibrosis

(2010) Anne-Karina T. Perl et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Goblet Cells Are Derived from aFOXJ1-Expressing Progenitor in a Human Airway Epithelium

(2010) Jonathan Turner et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Context-Dependent Differentiation of Multipotential Keratin 14–Expressing Tracheal Basal Cells

(2010) Moumita Ghosh et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Use of a New-Generation Reverse Tetracycline Transactivator System for Quantitative Control of Conditional Gene Expression in the Murine Lung

(2010) Julia Duerr et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

In Vivo Fate Mapping and Expression Analysis Reveals Molecular Hallmarks of Prospectively Isolated Adult Neural Stem Cells

(2010) Ruth Beckervordersandforth et al.   Cell Stem Cell

Foxj1 regulates floor plate cilia architecture and modifies the response of cells to sonic hedgehog signalling

(2010) C. Cruz et al.   DEVELOPMENT

Signaling via Alk5 controls the ontogeny of lung Clara cells

(2010) Y. Xing et al.   DEVELOPMENT

The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum

(2010) Y. Cheng et al.   DEVELOPMENT

Fetal and postnatal lung defects reveal a novel and required role for Fgf8 in lung development

(2010) Shibin Yu et al.   DEVELOPMENTAL BIOLOGY

Patterning and plasticity in development of the respiratory lineage

(2010) Eric T. Domyan et al.   DEVELOPMENTAL DYNAMICS

Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling

(2010) J. R. Rock et al.   Disease Models & Mechanisms

Doxycycline attenuates acrolein-induced mucin production, in part by inhibiting MMP-9

(2010) Shuang Ren et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

(2010) M. Morimoto et al.   JOURNAL OF CELL SCIENCE

Evidence That SOX2 Overexpression Is Oncogenic in the Lung

(2010) Yun Lu et al.   PLoS One

FGF signaling is required for myofibroblast differentiation during alveolar regeneration

(2009) Anne-Karina T. Perl et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Deletion ofPtenExpands Lung Epithelial Progenitor Pools and Confers Resistance to Airway Injury

(2009) Caterina Tiozzo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Targeted Injury of Type II Alveolar Epithelial Cells Induces Pulmonary Fibrosis

(2009) Thomas H. Sisson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Directed Expression of Cre in Alveolar Epithelial Type 1 Cells

(2009) Per Flodby et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium

(2009) Emma L. Rawlins et al.   Cell Stem Cell

The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells

(2009) E. L. Rawlins et al.   DEVELOPMENT

Notch signaling controls the balance of ciliated and secretory cell fates in developing airways

(2009) P.-N. Tsao et al.   DEVELOPMENT

Notch signaling promotes airway mucous metaplasia and inhibits alveolar development

(2009) J. S. Guseh et al.   DEVELOPMENT

Multiple roles for Sox2 in the developing and adult mouse trachea

(2009) J. Que et al.   DEVELOPMENT

Stabilized β-catenin in lung epithelial cells changes cell fate and leads to tracheal and bronchial polyposis

(2009) Changgong Li et al.   DEVELOPMENTAL BIOLOGY

Conditional gene inactivation reveals roles forFgf10andFgfr2in establishing a normal pattern of epithelial branching in the mouse lung

(2009) Lisa L. Abler et al.   DEVELOPMENTAL DYNAMICS

Split-Cre Complementation Indicates Coincident Activity of Different Genes In Vivo

(2009) Johannes Hirrlinger et al.   PLoS One

Silencing Inhibits Cre-Mediated Recombination of the Z/AP and Z/EG Reporters in Adult Cells

(2009) Michael A. Long et al.   PLoS One

Split-CreERT2: Temporal Control of DNA Recombination Mediated by Split-Cre Protein Fragment Complementation

(2009) Johannes Hirrlinger et al.   PLoS One

Stem cells are dispensable for lung homeostasis but restore airways after injury

(2009) A. Giangreco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -Catenin promotes respiratory progenitor identity in mouse foregut

(2009) K. S. Harris-Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Basal cells as stem cells of the mouse trachea and human airway epithelium

(2009) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ciliated epithelial cell lifespan in the mouse trachea and lung

(2008) Emma L. Rawlins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Directed Expression of Transgenes to Alveolar Type I Cells in the Mouse

(2008) Jeff N. Vanderbilt et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Conditional Expression of Genes in the Respiratory Epithelium in Transgenic Mice

(2008) Anne-Karina Perl et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer

(2008) A. J. Trimboli et al.   CANCER RESEARCH

Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells

(2008) Jared S. Burlison et al.   DEVELOPMENTAL BIOLOGY

An FGF–WNT gene regulatory network controls lung mesenchyme development

(2008) Yongjun Yin et al.   DEVELOPMENTAL BIOLOGY

rtTA toxicity limits the usefulness of the SP-C-rtTA transgenic mouse

(2008) Mitsuru Morimoto et al.   DEVELOPMENTAL BIOLOGY

Tissue-specific expression of Cre recombinase from theTgfb3 locus

(2008) Liang-Tung Yang et al.   GENESIS

Cre-mediated recombination in mouse Clara cells

(2008) HuaiGuang Li et al.   GENESIS

Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse

(2008) Olivia Wendling et al.   GENESIS

Next generation tools for high-throughput promoter and expression analysis employing single-copy knock-ins at the Hprt1 locus

(2008) G.S. Yang et al.   GENOMICS

Targeted Disruption of NeuroD, a Proneural Basic Helix-Loop-Helix Factor, Impairs Distal Lung Formation and Neuroendocrine Morphology in the Neonatal Lung

(2008) Enid R. Neptune et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of Adeno-associated Virus Progenitor Cell Transduction in Mouse Lung

(2008) Xiaoming Liu et al.   MOLECULAR THERAPY

Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart

(2008) Bin Zhou et al.   NATURE

Foxj1 transcription factors are master regulators of the motile ciliogenic program

(2008) Xianwen Yu et al.   NATURE GENETICS

Germ line activation of the Tie2 and SMMHC promoters causes noncell-specific deletion of floxed alleles

(2008) Willem J. de Lange et al.   PHYSIOLOGICAL GENOMICS

Formation and Differentiation of Multiple Mesenchymal Lineages during Lung Development Is Regulated by β-catenin Signaling

(2008) Stijn P. De Langhe et al.   PLoS One

Characterization of Parameters Required for Effective Use of Tamoxifen-Regulated Recombination

(2008) Ben Buelow et al.   PLoS One

Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development

(2008) J. Que et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conditional Stabilization of β-Catenin Expands the Pool of Lung Stem Cells

(2008) Susan D. Reynolds et al.   STEM CELLS

Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction

(2007) Guetchyn Millien et al.   GENE EXPRESSION PATTERNS

Type II Pneumocyte-Restricted Green Fluorescent Protein Expression After Lentiviral Transduction of Lung Epithelial Cells

(2007) Stephanie Wunderlich et al.   HUMAN GENE THERAPY

Fate mapping Nkx2.1-lineage cells in the mouse telencephalon

(2007) Qing Xu et al.   JOURNAL OF COMPARATIVE NEUROLOGY