Influence of Common Mucosal Co-Factors on HIV Infection in the Female Genital Tract

The Role of Serpin and Cystatin Antiproteases in Mucosal Innate Immunity and their Defense against HIV

(2013) Lindsay Aboud et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Hormonal Contraception and HIV-1 Infection: Medroxyprogesterone Acetate Suppresses Innate and Adaptive Immune Mechanisms

(2013) Richard P. H. Huijbregts et al.   ENDOCRINOLOGY

Plasma and Mucosal HIV Viral Loads Are Associated With Genital Tract Inflammation in HIV-Infected Women

(2013) Betsy C. Herold et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

HIV-1 gp120 Induces TLR2- and TLR4-Mediated Innate Immune Activation in Human Female Genital Epithelium

(2013) A. Nazli et al.   JOURNAL OF IMMUNOLOGY

Postintegration HIV-1 Infection of Cervical Epithelial Cells Mediates Contact-Dependent Productive Infection of T Cells

(2013) Amanda M. Micsenyi et al.   JOURNAL OF INFECTIOUS DISEASES

Higher Expression of Several Interferon-Stimulated Genes in HIV-1-Infected Females After Adjusting for the Level of Viral Replication

(2013) J. Judy Chang et al.   JOURNAL OF INFECTIOUS DISEASES

Defining the Interaction of HIV-1 with the Mucosal Barriers of the Female Reproductive Tract

(2013) A. M. Carias et al.   JOURNAL OF VIROLOGY

The end of AIDS: HIV infection as a chronic disease

(2013) Steven G Deeks et al.   LANCET

Productive HIV-1 infection of human cervical tissue ex vivo is associated with the secretory phase of the menstrual cycle

(2013) E Saba et al.   Mucosal Immunology

MX2 is an interferon-induced inhibitor of HIV-1 infection

(2013) Melissa Kane et al.   NATURE

Interferon-α Is the Primary Plasma Type-I IFN in HIV-1 Infection and Correlates with Immune Activation and Disease Markers

(2013) Gareth A. D. Hardy et al.   PLoS One

Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus

(2013) Jan Münch et al.   Retrovirology

Selective transmigration of monocyte-associated HIV-1 across a human cervical monolayer and its modulation by seminal plasma

(2012) Philip Lawrence et al.   AIDS

Depot Medroxyprogesterone Acetate Increases Immune Cell Numbers and Activation Markers in Human Vaginal Mucosal Tissues

(2012) Neelima Chandra et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

IFN-λ inhibits HIV-1 integration and post-transcriptional events in vitro, but there is only limited in vivo repression of viral production

(2012) Ren-Rong Tian et al.   ANTIVIRAL RESEARCH

Seminal Plasma Induces Prostaglandin-Endoperoxide Synthase (PTGS) 2 Expression in Immortalized Human Vaginal Cells: Involvement of Semen Prostaglandin E2 in PTGS2 Upregulation1

(2012) Theresa Joseph et al.   BIOLOGY OF REPRODUCTION

Seminal Fluid Induces Leukocyte Recruitment and Cytokine and Chemokine mRNA Expression in the Human Cervix after Coitus

(2012) D. J. Sharkey et al.   JOURNAL OF IMMUNOLOGY

Role of novel type I interferon epsilon in viral infection and mucosal immunity

(2012) Yang Xi et al.   Mucosal Immunology

Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection

(2012) N R Klatt et al.   Mucosal Immunology

A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis

(2012) C J Kim et al.   Mucosal Immunology

IFN-λ3 Inhibits HIV Infection of Macrophages through the JAK-STAT Pathway

(2012) Man-Qing Liu et al.   PLoS One

Endometrial epithelial cell response to semen from HIV-infected men during different stages of infection is distinct and can drive HIV-1-long terminal repeat

(2011) Jessica K. Kafka et al.   AIDS

Peptides Released by Physiological Cleavage of Semen Coagulum Proteins Form Amyloids that Enhance HIV Infection

(2011) Nadia R. Roan et al.   Cell Host & Microbe

Semen Clusterin Is a Novel DC-SIGN Ligand

(2011) Juan Sabatte et al.   JOURNAL OF IMMUNOLOGY

Semen of HIV-1–Infected Individuals: Local Shedding of Herpesviruses and Reprogrammed Cytokine Network

(2011) Andrea Lisco et al.   JOURNAL OF INFECTIOUS DISEASES

Endometrial Epithelial Cell Responses to Coinfecting Viral and Bacterial Pathogens in the Genital Tract Can Activate the HIV-1 LTR in an NFκB-and AP-1–Dependent Manner

(2011) Victor H. Ferreira et al.   JOURNAL OF INFECTIOUS DISEASES

Plasma Levels of Soluble CD14 Independently Predict Mortality in HIV Infection

(2011) Netanya G. Sandler et al.   JOURNAL OF INFECTIOUS DISEASES

Increased prevalence of sexually transmitted viral infections in women: the role of female sex hormones in regulating susceptibility and immune responses

(2011) Charu Kaushic et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Naturally Occurring Fragments from Two Distinct Regions of the Prostatic Acid Phosphatase Form Amyloidogenic Enhancers of HIV Infection

(2011) F. Arnold et al.   JOURNAL OF VIROLOGY

Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study

(2011) Renee Heffron et al.   LANCET INFECTIOUS DISEASES

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

(2011) Nadine Laguette et al.   NATURE

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

(2011) Kasia Hrecka et al.   NATURE

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22

(2011) Gregory F Sonnenberg et al.   NATURE IMMUNOLOGY

HIV Infection in the Female Genital Tract: Discrete Influence of the Local Mucosal Microenvironment

(2010) Charu Kaushic et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Early Events in Sexual Transmission of HIV and SIV and Opportunities for Interventions

(2010) Ashley T. Haase   Annual Review of Medicine

Sex Steroid Hormones, Hormonal Contraception, and the Immunobiology of Human Immunodeficiency Virus-1 Infection

(2010) Zdenek Hel et al.   ENDOCRINE REVIEWS

HIV‐Exposed Seronegative Commercial Sex Workers Show a Quiescent Phenotype in the CD4+T Cell Compartment and Reduced Expression of HIV‐Dependent Host Factors

(2010) Paul J. McLaren et al.   JOURNAL OF INFECTIOUS DISEASES

Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI

(2010) Kyeong-Ae Kim et al.   Retrovirology

Th17 cells, HIV and the gut mucosal barrier

(2010) Satya Dandekar et al.   Current Opinion in HIV and AIDS

Exposure to HIV-1 Directly Impairs Mucosal Epithelial Barrier Integrity Allowing Microbial Translocation

(2010) Aisha Nazli et al.   PLoS Pathogens

Early events in HIV transmission through a human reconstructed vaginal mucosa

(2009) Marielle Bouschbacher et al.   AIDS

Bacterial vaginosis and HIV acquisition: a meta-analysis of published studies

(2009) Julius Atashili et al.   AIDS

Cationic polypeptides contribute to the anti-HIV-1 activity of human seminal plasma

(2009) Julie A. Martellini et al.   FASEB JOURNAL

Depletion of CD4+ T Cells in Semen During HIV Infection and Their Restoration Following Antiretroviral Therapy

(2009) Joseph A Politch et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells

(2009) Ana Ceballos et al.   JOURNAL OF EXPERIMENTAL MEDICINE

gp340 Promotes Transcytosis of Human Immunodeficiency Virus Type 1 in Genital Tract-Derived Cell Lines and Primary Endocervical Tissue

(2009) E. Stoddard et al.   JOURNAL OF VIROLOGY

Human Immunodeficiency Virus Type 1 Is Trapped by Acidic but Not by Neutralized Human Cervicovaginal Mucus

(2009) S. K. Lai et al.   JOURNAL OF VIROLOGY

Lambda Interferon Inhibits Human Immunodeficiency Virus Type 1 Infection of Macrophages

(2009) W. Hou et al.   JOURNAL OF VIROLOGY

Differential expression and regulation of nuclear oligomerization domain proteins NOD1 and NOD2 in human endometrium: a potential role in innate immune protection and menstruation

(2009) A. E. King et al.   MOLECULAR HUMAN REPRODUCTION

Glycerol monolaurate prevents mucosal SIV transmission

(2009) Qingsheng Li et al.   NATURE

Persistence of HIV-1 receptor–positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition

(2009) Jia Zhu et al.   NATURE MEDICINE

Microbial translocation, the innate cytokine response, and HIV-1 disease progression in Africa

(2009) A. D. Redd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estradiol improves genital herpes vaccine efficacy in mice

(2009) Jeffry W. Pennock et al.   VACCINE

Mucin 6 in seminal plasma binds DC-SIGN and potently blocks dendritic cell mediated transfer of HIV-1 to CD4+ T-lymphocytes

(2009) Martijn J. Stax et al.   VIROLOGY

HIV/AIDS: Hormonal Contraception and HIV Disease Progression

(2008) Elizabeth Stringer et al.   CLINICAL INFECTIOUS DISEASES

Bacterial Vaginosis in HIV-Infected Women Induces Reversible Alterations in the Cervical Immune Environment

(2008) Anuradha Rebbapragada et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

The Cationic Properties of SEVI Underlie Its Ability To Enhance Human Immunodeficiency Virus Infection

(2008) N. R. Roan et al.   JOURNAL OF VIROLOGY

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

The Effect of Genital Tract Infections on HIV-1 Shedding in the Genital Tract: A Systematic Review and Meta-Analysis

(2008) Leigh F. Johnson et al.   SEXUALLY TRANSMITTED DISEASES

Influence of different semen extenders and seminal plasma on PMN migration and on expression of IL-1β, IL-6, TNF-α and COX-2 mRNA in the equine endometrium

(2008) F. Palm et al.   THERIOGENOLOGY

Intranasal and subcutaneous immunization under the effect of estradiol leads to better protection against genital HSV-2 challenge compared to progesterone

(2008) Sudha Bhavanam et al.   VACCINE

The mucosal barrier and immune activation in HIV pathogenesis

(2008) Jason M Brenchley et al.   Current Opinion in HIV and AIDS