The Role of Serpin and Cystatin Antiproteases in Mucosal Innate Immunity and their Defense against HIV

Serine protease inhibitors and cytotoxic T lymphocytes

(2015) Philip G. Ashton-Rickardt   IMMUNOLOGICAL REVIEWS

A Helminth Immunomodulator Reduces Allergic and Inflammatory Responses by Induction of IL-10-Producing Macrophages

(2014) C. Schnoeller et al.   JOURNAL OF IMMUNOLOGY

Safety of tenofovir gel, a vaginal microbicide, in South African women: results of the CAPRISA 004 Trial

(2012) David C Sokal et al.   ANTIVIRAL THERAPY

Antiretroviral-based HIV-1 prevention: antiretroviral treatment and pre-exposure prophylaxis

(2012) Connie Celum et al.   ANTIVIRAL THERAPY

War and peace between WAP and HIV: role of SLPI, trappin-2, elafin and ps20 in susceptibility to HIV infection

(2012) Anna G. Drannik et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Alpha-1-antitrypsin inhibits nitric oxide production

(2012) Edward D. Chan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

In Vivo Anti-HIV Activity of the Heparin-Activated Serine Protease Inhibitor Antithrombin III Encapsulated in Lymph-Targeting Immunoliposomes

(2012) Mohammed Asmal et al.   PLoS One

Innate Immunity in the Human Female Reproductive Tract: Endocrine Regulation of Endogenous Antimicrobial Protection Against HIV and Other Sexually Transmitted Infections

(2011) Charles R. Wira et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

HIV Replication in CD4+ T Lymphocytes in the Presence and Absence of Follicular Dendritic Cells: Inhibition of Replication Mediated by  -1-Antitrypsin through Altered I B  Ubiquitination

(2011) X. Zhou et al.   JOURNAL OF IMMUNOLOGY

IL-10 Controls Cystatin C Synthesis and Blood Concentration in Response to Inflammation through Regulation of IFN Regulatory Factor 8 Expression

(2011) Y. Xu et al.   JOURNAL OF IMMUNOLOGY

Comprehensive Proteomic Study Identifies Serpin and Cystatin Antiproteases as Novel Correlates of HIV-1 Resistance in the Cervicovaginal Mucosa of Female Sex Workers

(2011) A. Burgener et al.   JOURNAL OF PROTEOME RESEARCH

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(2011) Mariam Al-Omari et al.   MOLECULAR MEDICINE

Coming of age: reconstruction of heterosexual HIV-1 transmission in human ex vivo organ culture systems

(2011) P J Southern et al.   Mucosal Immunology

Serpin Induced Antiviral Activity of Prostaglandin Synthetase-2 against HIV-1 Replication

(2011) James B. Whitney et al.   PLoS One

Inhibition of lung serine proteases in mice: a potentially new approach to control influenza infection

(2011) Mahmoud M Bahgat et al.   Virology Journal

Cytokines regulate cysteine cathepsins during TLR responses

(2010) Blaine M. Creasy et al.   CELLULAR IMMUNOLOGY

Serpins Flex Their Muscle

(2010) James C. Whisstock et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serpins Flex Their Muscle

(2010) Gary A. Silverman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cohorts for the Study of HIV‐1–Exposed but Uninfected Individuals: Benefits and Limitations

(2010) R. E. Horton et al.   JOURNAL OF INFECTIOUS DISEASES

Cathepsins (S and B) and their inhibitor Cystatin C in immune cells: Modulation by interferon-β and role played in cell migration

(2010) Elsebeth Staun-Ram et al.   JOURNAL OF NEUROIMMUNOLOGY

Serine proteases of the human immune system in health and disease

(2010) Kirstin M. Heutinck et al.   MOLECULAR IMMUNOLOGY

HIV-1 sexual transmission: early events of HIV-1 infection of human cervico-vaginal tissue in an optimized ex vivo model

(2010) E Saba et al.   Mucosal Immunology

Short-Term Monotherapy in HIV-Infected Patients with a Virus Entry Inhibitor Against the gp41 Fusion Peptide

(2010) W.-G. Forssmann et al.   Science Translational Medicine

Exposure to HIV-1 Directly Impairs Mucosal Epithelial Barrier Integrity Allowing Microbial Translocation

(2010) Aisha Nazli et al.   PLoS Pathogens

Elevated elafin/trappin-2 in the female genital tract is associated with protection against HIV acquisition

(2009) Shehzad M Iqbal et al.   AIDS

Development of topical microbicides to prevent the sexual transmission of HIV

(2009) Robert W. Buckheit et al.   ANTIVIRAL RESEARCH

Cathepsin G Recruits Osteoclast Precursors via Proteolytic Activation of Protease-Activated Receptor-1

(2009) T. J. Wilson et al.   CANCER RESEARCH

Microbicides and HIV prevention: lessons from the past, looking to the future

(2009) Georgina C Morris et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Trappin-2/Elafin: a novel innate anti-human immunodeficiency virus-1 molecule of the human female reproductive tract

(2009) Mimi Ghosh et al.   IMMUNOLOGY

α-1-Antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood

(2009) Gregory B. Pott et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Glycerol monolaurate prevents mucosal SIV transmission

(2009) Qingsheng Li et al.   NATURE

Cystatin B Associates with Signal Transducer and Activator of Transcription 1 in Monocyte-Derived and Placental Macrophages

(2009) C. Luciano-Montalvo et al.   PLACENTA

The Phospholipid Scramblases 1 and 4 Are Cellular Receptors for the Secretory Leukocyte Protease Inhibitor and Interact with CD4 at the Plasma Membrane

(2009) Bénédicte Py et al.   PLoS One

Intracellular and extracellular serpins modulate lung disease

(2008) D J Askew et al.   Journal of Perinatology

Identification of Differentially Expressed Proteins in the Cervical Mucosa of HIV-1-Resistant Sex Workers

(2008) Adam Burgener et al.   JOURNAL OF PROTEOME RESEARCH

The role of serpins in vertebrate immunity

(2008) M. S. J. Mangan et al.   TISSUE ANTIGENS

Novel innate immune functions of the whey acidic protein family

(2008) Colin D Bingle et al.   TRENDS IN IMMUNOLOGY

Multifaceted roles of human elafin and secretory leukocyte proteinase inhibitor (SLPI), two serine protease inhibitors of the chelonianin family

(2007) Thierry Moreau et al.   BIOCHIMIE