Myostatin is a key mediator between energy metabolism and endurance capacity of skeletal muscle

Local overexpression of the myostatin propeptide increases glucose transporter expression and enhances skeletal muscle glucose disposal

(2014) M. E. Cleasby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Denervation atrophy is independent from Akt and mTOR activation and is not rescued by myostatin inhibition

(2014) E. M. MacDonald et al.   Disease Models & Mechanisms

Lack of myostatin impairs mechanical performance and ATP cost of contraction in exercising mouse gastrocnemius muscle in vivo

(2013) Benoît Giannesini et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1α-Fndc5 pathway in muscle

(2013) Tizhong Shan et al.   FASEB JOURNAL

Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism

(2013) Zhenji Gan et al.   JOURNAL OF CLINICAL INVESTIGATION

Lack of myostatin alters intermyofibrillar mitochondria activity, unbalances redox status, and impairs tolerance to chronic repetitive contractions in muscle

(2012) Claire Ploquin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Muscle protein synthesis, mTORC1/MAPK/Hippo signaling, and capillary density are altered by blocking of myostatin and activins

(2012) Juha J. Hulmi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Blockade of the Activin Receptor IIB Activates Functional Brown Adipogenesis and Thermogenesis by Inducing Mitochondrial Oxidative Metabolism

(2012) B. Fournier et al.   MOLECULAR AND CELLULAR BIOLOGY

Protection from Obesity and Diabetes by Blockade of TGF-β/Smad3 Signaling

(2011) Hariom Yadav et al.   Cell Metabolism

Soluble activin receptor type IIB treatment does not cause fat loss in mice with diet-induced obesity

(2011) A. C. McPherron et al.   DIABETES OBESITY & METABOLISM

Myostatin-deficient mice exhibit reduced insulin resistance through activating the AMP-activated protein kinase signalling pathway

(2011) C. Zhang et al.   DIABETOLOGIA

Exercise training attenuates the hypermuscular phenotype and restores skeletal muscle function in the myostatin null mouse

(2011) Antonios Matsakas et al.   EXPERIMENTAL PHYSIOLOGY

Is functional hypertrophy and specific force coupled with the addition of myonuclei at the single muscle fiber level?

(2011) Rizwan Qaisar et al.   FASEB JOURNAL

Follistatin and Follistatin Like-3 Differentially Regulate Adiposity and Glucose Homeostasis

(2011) Melissa L. Brown et al.   Obesity

Gene expression profiling of skeletal muscles treated with a soluble activin type IIB receptor

(2011) Fedik Rahimov et al.   PHYSIOLOGICAL GENOMICS

Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival

(2010) Xiaolan Zhou et al.   CELL

Genetic Deletion of Myostatin From the Heart Prevents Skeletal Muscle Atrophy in Heart Failure

(2010) Joerg Heineke et al.   CIRCULATION

Antibody-directed myostatin inhibition in 21-mo-old mice reveals novel roles for myostatin signaling in skeletal muscle structure and function

(2010) Kate T. Murphy et al.   FASEB JOURNAL

Mechanisms involved in the enhancement of mammalian target of rapamycin signalling and hypertrophy in skeletal muscle of myostatin-deficient mice

(2010) Christopher Lipina et al.   FEBS LETTERS

Administration of a soluble activin type IIB receptor promotes skeletal muscle growth independent of fiber type

(2010) Samuel M. Cadena et al.   JOURNAL OF APPLIED PHYSIOLOGY

Metabolic fuels: regulating fluxes to select mix

(2010) J.-M. Weber   JOURNAL OF EXPERIMENTAL BIOLOGY

Myostatin knockout mice increase oxidative muscle phenotype as an adaptive response to exercise

(2010) Antonios Matsakas et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Endurance exercise training in myostatin null mice

(2010) Kathleen J. Savage et al.   MUSCLE & NERVE

Activin IIB receptor blockade attenuates dystrophic pathology in a mouse model of duchenne muscular dystrophy

(2010) Kevin J. Morine et al.   MUSCLE & NERVE

Postnatal PPARδ Activation and Myostatin Inhibition Exert Distinct yet Complimentary Effects on the Metabolic Profile of Obese Insulin-Resistant Mice

(2010) Barbara L. Bernardo et al.   PLoS One

Myostatin regulates fiber-type composition of skeletal muscle by regulating MEF2 and MyoD gene expression

(2009) Alex Hennebry et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Functional assessment of skeletal muscle in intact mice lacking myostatin by concurrent NMR imaging and spectroscopy

(2009) C Baligand et al.   GENE THERAPY

The effects of a soluble activin type IIB receptor on obesity and insulin sensitivity

(2009) I Akpan et al.   INTERNATIONAL JOURNAL OF OBESITY

Peroxisome proliferator-activated receptor beta/delta (PPARβ/δ) acts as regulator of metabolism linked to multiple cellular functions

(2009) Kay-Dietrich Wagner et al.   PHARMACOLOGY & THERAPEUTICS

Slow myosin heavy chain expression in the absence of muscle activity

(2008) O. Agbulut et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Muscle 3243A→G mutation load and capacity of the mitochondrial energy-generating system

(2008) Antoon J. M. Janssen et al.   ANNALS OF NEUROLOGY