Autophagy is essential to support skeletal muscle plasticity in response to endurance exercise

Exercise-Induced Skeletal Muscle Remodeling and Metabolic Adaptation: Redox Signaling and Role of Autophagy

(2014) Elisabetta Ferraro et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of ubiquitin-proteasome and autophagy pathways after acute LPS and epoxomicin administration in mice

(2014) Cécile Jamart et al.   BMC MUSCULOSKELETAL DISORDERS

Autophagy and Protein Turnover Signaling in Slow-Twitch Muscle during Exercise

(2014) ALLAN F. PAGANO et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Autophagic Cellular Responses to Physical Exercise in Skeletal Muscle

(2014) Bjorn T. Tam et al.   SPORTS MEDICINE

Exercise ameliorates the detrimental effect of chloroquine on skeletal muscles in mice via restoring autophagy flux

(2013) Dan Jiang et al.   ACTA PHARMACOLOGICA SINICA

p53 is necessary for the adaptive changes in cellular milieu subsequent to an acute bout of endurance exercise

(2013) Ayesha Saleem et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Higher activation of autophagy in skeletal muscle of mice during endurance exercise in the fasted state

(2013) Cécile Jamart et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reactive Oxygen Species Regulation of Autophagy in Skeletal Muscles

(2013) Mashrur Rahman et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagic flux and oxidative capacity of skeletal muscles during acute starvation

(2013) Mahroo Mofarrahi et al.   Autophagy

Can we optimise the exercise training prescription to maximise improvements in mitochondria function and content?

(2013) David J. Bishop et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy

(2013) Perrine Castets et al.   Cell Metabolism

FoxO transcription factors: their roles in the maintenance of skeletal muscle homeostasis

(2013) Anthony M. J. Sanchez et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats

(2013) Li Luo et al.   EXPERIMENTAL GERONTOLOGY

Autophagy is required for exercise training-induced skeletal muscle adaptation and improvement of physical performance

(2013) Vitor A. Lira et al.   FASEB JOURNAL

eIF3f: A central regulator of the antagonism atrophy/hypertrophy in skeletal muscle

(2013) Anthony M.J. Sanchez et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Role of Diacylglycerol Kinase ζ and Phosphatidic Acid in the Mechanical Activation of Mammalian Target of Rapamycin (mTOR) Signaling and Skeletal Muscle Hypertrophy

(2013) Jae-Sung You et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Skeletal muscle, autophagy, and physical activity: the ménage à trois of metabolic regulation in health and disease

(2013) Anna Vainshtein et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Autophagic response to exercise training in skeletal muscle with age

(2013) Yong An Kim et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

Sprint exercise enhances skeletal muscle p70S6k phosphorylation and more so in women than in men

(2012) M. Esbjörnsson et al.   Acta Physiologica

The role of AMP-activated protein kinase in the coordination of skeletal muscle turnover and energy homeostasis

(2012) Anthony M. J. Sanchez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy

(2012) Jorge L. Ruas et al.   CELL

RETRACTED: The Ubiquitin Ligase Mul1 Induces Mitophagy in Skeletal Muscle in Response to Muscle-Wasting Stimuli

(2012) Sudarsanareddy Lokireddy et al.   Cell Metabolism

Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation

(2012) Julia Romanov et al.   EMBO JOURNAL

Modulation of autophagy and ubiquitin-proteasome pathways during ultra-endurance running

(2012) Cécile Jamart et al.   JOURNAL OF APPLIED PHYSIOLOGY

Withdrawal of Essential Amino Acids Increases Autophagy by a Pathway Involving Ca2+/Calmodulin-dependent Kinase Kinase-β (CaMKK-β)

(2012) Ghita Ghislat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitylation by Trim32 causes coupled loss of desmin, Z-bands, and thin filaments in muscle atrophy

(2012) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY

Skeletal Muscle Autophagy and Protein Breakdown Following Resistance Exercise are Similar in Younger and Older Adults

(2012) C. S. Fry et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

(2012) Congcong He et al.   NATURE

Autophagy and Skeletal Muscles in Sepsis

(2012) Mahroo Mofarrahi et al.   PLoS One

Mechanical Stimulation Induces mTOR Signaling via an ERK-Independent Mechanism: Implications for a Direct Activation of mTOR by Phosphatidic Acid

(2012) Jae Sung You et al.   PLoS One

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

(2012) C. Kondapalli et al.   Open Biology

Enhanced rates of muscle protein synthesis and elevated mTOR signalling following endurance exercise in human subjects

(2011) H. Mascher et al.   Acta Physiologica

Physical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI-deficient muscles

(2011) Paolo Grumati et al.   Autophagy

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

(2011) Dan Egan et al.   Autophagy

Ulk1-mediated phosphorylation of AMPK constitutes a negative regulatory feedback loop

(2011) Antje S. Löffler et al.   Autophagy

Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass

(2011) Craig A. Goodman et al.   CELLULAR SIGNALLING

Autophagy-related and autophagy-regulatory genes are induced in human muscle after ultraendurance exercise

(2011) Cécile Jamart et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Class III PI-3-kinase activates phospholipase D in an amino acid–sensing mTORC1 pathway

(2011) Mee-Sup Yoon et al.   JOURNAL OF CELL BIOLOGY

AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1

(2011) Anthony MJ Sanchez et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Autophagic response to a single bout of moderate exercise in murine skeletal muscle

(2011) Yong An Kim et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling

(2011) Mitsunori Miyazaki et al.   JOURNAL OF PHYSIOLOGY-LONDON

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

An Exploratory Analysis of the Effects of a Weight Loss Plus Exercise Program on Cellular Quality Control Mechanisms in Older Overweight Women

(2011) Stephanie E. Wohlgemuth et al.   REJUVENATION RESEARCH

Differentiated mTOR but not AMPK signaling after strength vs endurance exercise in training-accustomed individuals

(2011) K. Vissing et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis

(2011) Christopher S Fry et al.   Skeletal Muscle

Autophagy in health and disease. 3. Involvement of autophagy in muscle atrophy

(2010) Marco Sandri   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise

(2010) Erin L. Glynn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Ultraendurance exercise increases the production of reactive oxygen species in isolated mitochondria from human skeletal muscle

(2010) Kent Sahlin et al.   JOURNAL OF APPLIED PHYSIOLOGY

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

Endoplasmic Reticulum Stress Markers and Ubiquitin-Proteasome Pathway Activity in Response to a 200-km Run

(2010) HYO JEONG KIM et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Translation Regulatory Subunit eIF3f Controls the Kinase-Dependent mTOR Signaling Required for Muscle Differentiation and Hypertrophy in Mouse

(2010) Alfredo Csibi et al.   PLoS One

The Association of AMPK with ULK1 Regulates Autophagy

(2010) Jong Woo Lee et al.   PLoS One

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission

(2009) Emélie Braschi et al.   EMBO REPORTS

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

Identification of MAFbx as a myogenin-engaged F-box protein in SCF ubiquitin ligase

(2009) Misako Jogo et al.   FEBS LETTERS

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

(2009) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

(2009) Kasper M.A. Rouschop et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis

(2009) Micah J. Drummond et al.   JOURNAL OF PHYSIOLOGY-LONDON

Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men

(2009) Daniel W. D. West et al.   JOURNAL OF PHYSIOLOGY-LONDON

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene

(2008) David S. Waddell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

The effect of amino acid infusion on leg protein turnover assessed by L-[15N]phenylalanine and L-[1-13C]leucine exchange

(2008) W. M. BENNET et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Influence of leucine infusion on intracellular amino acids in humans

(2008) A. ALVESTRAND et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Exercise training and protein metabolism: influences of contraction, protein intake, and sex-based differences

(2008) Nicholas A. Burd et al.   JOURNAL OF APPLIED PHYSIOLOGY

MAFbx/Atrogin-1 Controls the Activity of the Initiation Factor eIF3-f in Skeletal Muscle Atrophy by Targeting Multiple C-terminal Lysines

(2008) Alfredo Csibi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mVps34 is activated following high-resistance contractions

(2008) Matthew G. MacKenzie et al.   JOURNAL OF PHYSIOLOGY-LONDON

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE

A functional insulin-like growth factor receptor is not necessary for load-induced skeletal muscle hypertrophy

(2007) Espen E. Spangenburg et al.   JOURNAL OF PHYSIOLOGY-LONDON