Mitochondrial morphology transitions and functions: implications for retrograde signaling?

Linking the Metabolic State and Mitochondrial DNA in Chronic Disease, Health, and Aging

(2013) M. Picard et al.   DIABETES

Mitochondrial Dysfunction and Lipid Accumulation in the Human Diaphragm during Mechanical Ventilation

(2012) Martin Picard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mitochondria: Starving to reach quorum?

(2012) Martin Picard et al.   BIOESSAYS

Dysfunctional mitochondrial maintenance: what breaks the circle of life?

(2012) P. Yu-Wai-Man et al.   BRAIN

Mitofusin 1 inhibits an apoptosis-associated amino-terminal conformational change in Bax, but not its mitochondrial translocation, in a GTPase-dependent manner

(2012) Seung-Wook Ryu et al.   CANCER LETTERS

The intracellular redox state is a core determinant of mitochondrial fusion

(2012) Timothy Shutt et al.   EMBO REPORTS

Mitofusin2 Mutations Disrupt Axonal Mitochondrial Positioning and Promote Axon Degeneration

(2012) A. L. Misko et al.   JOURNAL OF NEUROSCIENCE

Monogenic Mitochondrial Disorders

(2012) Werner J.H. Koopman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial functional specialization in glycolytic and oxidative muscle fibers: tailoring the organelle for optimal function

(2011) Martin Picard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Redox Regulation of Mitochondrial Function

(2011) Diane E. Handy et al.   ANTIOXIDANTS & REDOX SIGNALING

The MFN2 gene is responsible for mitochondrial DNA instability and optic atrophy 'plus' phenotype

(2011) C. Rouzier et al.   BRAIN

Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis

(2011) Andrea Rasola et al.   CELL CALCIUM

Protein Phosphorylation and Prevention of Cytochrome Oxidase Inhibition by ATP: Coupled Mechanisms of Energy Metabolism Regulation

(2011) Rebeca Acin-Perez et al.   Cell Metabolism

In Vivo Correction of COX Deficiency by Activation of the AMPK/PGC-1α Axis

(2011) Carlo Viscomi et al.   Cell Metabolism

Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes Mellitus

(2011) Sherene M. Shenouda et al.   CIRCULATION

Mitochondria-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness*

(2011) Scott K. Powers et al.   CRITICAL CARE MEDICINE

The Permeability Transition Pore Controls Cardiac Mitochondrial Maturation and Myocyte Differentiation

(2011) Jennifer R. Hom et al.   DEVELOPMENTAL CELL

Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis

(2011) Guillaume Pidoux et al.   EMBO JOURNAL

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

Redefining our menu: Communications and Reviews

(2011) Edward N. Pugh   JOURNAL OF GENERAL PHYSIOLOGY

Mitochondrial DNA and disease

(2011) Laura C Greaves et al.   JOURNAL OF PATHOLOGY

Mitochondrial Fission Contributes to Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle

(2011) H.-F. Jheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

(2011) Joshua M. Baughman et al.   NATURE

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

Mitochondria unite to survive

(2011) Craig Blackstone et al.   NATURE CELL BIOLOGY

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Mitochondrial Structure and Function Are Disrupted by Standard Isolation Methods

(2011) Martin Picard et al.   PLoS One

The Effect of OPA1 on Mitochondrial Ca2+ Signaling

(2011) László Fülöp et al.   PLoS One

Mitochondrial Membrane Potential Is Required for MAVS-Mediated Antiviral Signaling

(2011) T. Koshiba et al.   Science Signaling

AMP-activated protein kinase: also regulated by ADP?

(2011) D. Grahame Hardie et al.   TRENDS IN BIOCHEMICAL SCIENCES

Biophysical properties of mitochondrial fusion events in pancreatic β-cells and cardiac cells unravel potential control mechanisms of its selectivity

(2010) Gilad Twig et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Redefining the role of mitochondria in exercise: a dynamic remodeling

(2010) Hai Bo et al.   Annals of the New York Academy of Sciences

Role of mitochondrial reactive oxygen species in osteoclast differentiation

(2010) Satish Srinivasan et al.   Annals of the New York Academy of Sciences

Physiological functions of mitochondrial fusion

(2010) Hsiuchen Chen et al.   Annals of the New York Academy of Sciences

Biological Functions and Biogenesis of Secreted Bacterial Outer Membrane Vesicles

(2010) Adam Kulp et al.   Annual Review of Microbiology

Redox Control Systems in the Nucleus: Mechanisms and Functions

(2010) Young-Mi Go et al.   ANTIOXIDANTS & REDOX SIGNALING

Balancing Mitochondrial Redox Signaling: A Key Point in Metabolic Regulation

(2010) Corinne Leloup et al.   ANTIOXIDANTS & REDOX SIGNALING

The Interplay Between Mitochondrial Dynamics and Mitophagy

(2010) Gilad Twig et al.   ANTIOXIDANTS & REDOX SIGNALING

Multi-site control and regulation of mitochondrial energy production

(2010) G. Benard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

(2010) Sang-Bing Ong et al.   CIRCULATION

AMPK-mediated regulation of transcription in skeletal muscle

(2010) Sean L. McGee et al.   CLINICAL SCIENCE

Mitochondrial Function: OMA1 and OPA1, the Grandmasters of Mitochondrial Health

(2010) Heidi McBride et al.   CURRENT BIOLOGY

Bioenergetics and the epigenome: Interface between the environment and genes in common diseases

(2010) Douglas C. Wallace   Developmental Disabilities Research Reviews

Mitochondrial fission and remodelling contributes to muscle atrophy

(2010) Vanina Romanello et al.   EMBO JOURNAL

The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

(2010) Riekelt H. Houtkooper et al.   ENDOCRINE REVIEWS

Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation

(2010) Padma Madiraju et al.   Epigenetics

Roles of mitochondria in human disease: Figure 1

(2010) Michael R. Duchen et al.   Essays in Biochemistry

Oxidative stress causes reversible changes in mitochondrial permeability and structure

(2010) Nelson B. Cole et al.   EXPERIMENTAL GERONTOLOGY

H2O2-induced mitochondrial fragmentation in C2C12 myocytes

(2010) Xiying Fan et al.   FREE RADICAL BIOLOGY AND MEDICINE

OPA1 mutations cause cytochrome c oxidase deficiency due to loss of wild-type mtDNA molecules

(2010) Patrick Yu-Wai-Man et al.   HUMAN MOLECULAR GENETICS

Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

(2010) John W. Elrod et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitofusin 2 Is Necessary for Transport of Axonal Mitochondria and Interacts with the Miro/Milton Complex

(2010) A. Misko et al.   JOURNAL OF NEUROSCIENCE

VDAC, a multi-functional mitochondrial protein regulating cell life and death

(2010) Varda Shoshan-Barmatz et al.   MOLECULAR ASPECTS OF MEDICINE

The energetics of genome complexity

(2010) Nick Lane et al.   NATURE

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bioenergetics, the origins of complexity, and the ascent of man

(2010) D. C. Wallace   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells

(2010) D.-F. Suen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial fusion proteins: Dual regulators of morphology and metabolism

(2010) Antonio Zorzano et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mechanisms Shaping the Membranes of Cellular Organelles

(2009) Yoko Shibata et al.   Annual Review of Cell and Developmental Biology

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics

Mechanisms of exercise-induced mitochondrial biogenesis in skeletal muscleThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.

(2009) David A. Hood   Applied Physiology Nutrition and Metabolism

Modulation of calcium signalling by mitochondria

(2009) Ciara Walsh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

SR/ER–mitochondrial local communication: Calcium and ROS

(2009) György Csordás et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway

(2009) G Liot et al.   CELL DEATH AND DIFFERENTIATION

Superoxide is the major reactive oxygen species regulating autophagy

(2009) Y Chen et al.   CELL DEATH AND DIFFERENTIATION

New insights into mitochondrial structure during cell death

(2009) Guy Perkins et al.   EXPERIMENTAL NEUROLOGY

Effect of Transient and Permanent Permeability Transition Pore Opening on NAD(P)H Localization in Intact Cells

(2009) Jean François Dumas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Phenotypic spectrum of MFN2 mutations in the Spanish population

(2009) C. Casasnovas et al.   JOURNAL OF MEDICAL GENETICS

Morphological dynamics of mitochondria — A special emphasis on cardiac muscle cells

(2009) Jennifer Hom et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Energetics, epigenetics, mitochondrial genetics

(2009) Douglas C. Wallace et al.   MITOCHONDRION

Mitofusins and OPA1 Mediate Sequential Steps in Mitochondrial Membrane Fusion

(2009) Zhiyin Song et al.   MOLECULAR BIOLOGY OF THE CELL

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Mitochondrial Dynamics in Mammalian Health and Disease

(2009) Marc Liesa et al.   PHYSIOLOGICAL REVIEWS

The changing shape of mitochondrial apoptosis

(2009) Michał Wasilewski et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mitochondrial dynamics as a bridge between mitochondrial dysfunction and insulin resistance

(2009) Antonio Zorzano et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Ultrastructure of the Mitochondrion and Its Bearing on Function and Bioenergetics

(2008) Giovanni Benard et al.   ANTIOXIDANTS & REDOX SIGNALING

Calcium regulation of mitochondria motility and morphology

(2008) Danny V. Jeyaraju et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Positioning mitochondrial plasticity within cellular signaling cascades

(2008) Vincent Soubannier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Supramolecular organization of protein complexes in the mitochondrial inner membrane

(2008) Janet Vonck et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species

(2008) Tianzheng Yu et al.   CARDIOVASCULAR RESEARCH

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

Superoxide Flashes in Single Mitochondria

(2008) Wang Wang et al.   CELL

Cargo-Selected Transport from the Mitochondria to Peroxisomes Is Mediated by Vesicular Carriers

(2008) Margaret Neuspiel et al.   CURRENT BIOLOGY

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Acetylation of non-histone proteins modulates cellular signalling at multiple levels

(2008) Stephanie Spange et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Short- and long-term alterations of mitochondrial morphology, dynamics and mtDNA after transient oxidative stress

(2008) Marina Jendrach et al.   MITOCHONDRION

Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications

(2008) Xiang-Jiao Yang et al.   MOLECULAR CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint

(2008) Edward Owusu-Ansah et al.   NATURE GENETICS

Modulation of mitochondrial morphology by bioenergetics defects in primary human fibroblasts

(2008) O. Guillery et al.   NEUROMUSCULAR DISORDERS

Mitochondria: The Hub of Cellular Ca2+ Signaling

(2008) György Szabadkai et al.   PHYSIOLOGY

Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA

(2008) Philippe A. Parone et al.   PLoS One

Quantitative phosphoproteomics - an emerging key technology in signal-transduction research

(2008) Thiemo B. Schreiber et al.   PROTEOMICS

OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes

(2007) P. Amati-Bonneau et al.   BRAIN