Maternal obesity and fetal metabolic programming: a fertile epigenetic soil

Maternal macronutrient and energy intakes in pregnancy and offspring intake at 10 y: exploring parental comparisons and prenatal effects

(2010) Marie-Jo A Brion et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Maternal obesity programmes offspring development of non-alcoholic fatty pancreas disease

(2010) Jude A. Oben et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Coordinated Chromatin Control: Structural and Functional Linkage of DNA and Histone Methylation

(2010) Xiaodong Cheng et al.   BIOCHEMISTRY

Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome — An allostatic perspective

(2010) Sam Virtue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Transcriptional Control of Gene Expression by MicroRNAs

(2010) Basel Khraiwesh et al.   CELL

Methylation analysis of 79 patients with growth restriction reveals novel patterns of methylation change at imprinted loci

(2010) Claire Louise Susan Turner et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Intrauterine Growth Retardation Leads to the Functional Change of Insulin Secretion in the Newborn Rats

(2010) Q. X. Yuan et al.   HORMONE AND METABOLIC RESEARCH

Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model

(2010) R. Scott Rector et al.   JOURNAL OF HEPATOLOGY

Chronic Consumption of a High-Fat Diet during Pregnancy Causes Perturbations in the Serotonergic System and Increased Anxiety-Like Behavior in Nonhuman Primate Offspring

(2010) E. L. Sullivan et al.   JOURNAL OF NEUROSCIENCE

Epigenetic modification of fetal baboon hepatic phosphoenolpyruvate carboxykinase following exposure to moderately reduced nutrient availability

(2010) Mark J. Nijland et al.   JOURNAL OF PHYSIOLOGY-LONDON

Prenatal Exposure to the Environmental Obesogen Tributyltin Predisposes Multipotent Stem Cells to Become Adipocytes

(2010) Séverine Kirchner et al.   MOLECULAR ENDOCRINOLOGY

Fetal programming: link between early nutrition, DNA methylation, and complex diseases

(2010) Agata Chmurzynska   NUTRITION REVIEWS

Maternal Diet-Induced Obesity Alters Mitochondrial Activity and Redox Status in Mouse Oocytes and Zygotes

(2010) Natalia Igosheva et al.   PLoS One

Perinatal risk factors for childhood obesity and metabolic dysregulation

(2009) Patrick M Catalano et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Differential regulation of genes for fetoplacental lipid pathways in pregnancy with gestational and type 1 diabetes mellitus

(2009) Tatiana Radaelli et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

IL-6 stimulates system A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2

(2009) H. N. Jones et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Fetal liver X receptor activation acutely induces lipogenesis but does not affect plasma lipid response to a high-fat diet in adult mice

(2009) Esther M. E. van Straten et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Oxidative stress in skeletal muscle impairs mitochondrial respiration and limits exercise capacity in type 2 diabetic mice

(2009) Takashi Yokota et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Maternal obesity accelerates fetal pancreatic β-cell but not α-cell development in sheep: prenatal consequences

(2009) Stephen P. Ford et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Maternal and postweaning diet interaction alters hypothalamic gene expression and modulates response to a high-fat diet in male offspring

(2009) Kathleen C. Page et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Maternal obesity is necessary for programming effect of high-fat diet on offspring

(2009) Christy L. White et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction

(2009) Esther M. E. van Straten et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

HDAC inhibitor-based therapies and haematological malignancy

(2009) L. Stimson et al.   ANNALS OF ONCOLOGY

Metabolic and Mitochondrial Dysfunction in Early Mouse Embryos Following Maternal Dietary Protein Intervention1

(2009) Megan Mitchell et al.   BIOLOGY OF REPRODUCTION

Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring

(2009) Junlong Zhang et al.   BMC GENOMICS

Risk factors for childhood obesity at age 5: Analysis of the Millennium Cohort Study

(2009) Sinead Brophy et al.   BMC PUBLIC HEALTH

Long-term maternal high-fat feeding from weaning through pregnancy and lactation predisposes offspring to hypertension, raised plasma lipids and fatty liver in mice

(2009) Maqsood M. Elahi et al.   BRITISH JOURNAL OF NUTRITION

Epigenetics in cancer

(2009) S. Sharma et al.   CARCINOGENESIS

Epigenetic Therapy: Histone Acetylation, DNA Methylation and Anti-Cancer Drug Discovery

(2009) A. Ganesan et al.   CURRENT CANCER DRUG TARGETS

Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

(2009) S. Fujisaka et al.   DIABETES

Hormonal and Metabolic Factors Associated With Variations in Insulin Sensitivity in Human Pregnancy

(2009) H. D. McIntyre et al.   DIABETES CARE

Fetuses of Obese Mothers Develop Insulin Resistance in Utero

(2009) P. M. Catalano et al.   DIABETES CARE

Up-Regulation of Toll-Like Receptor 4/Nuclear Factor-κB Signaling Is Associated with Enhanced Adipogenesis and Insulin Resistance in Fetal Skeletal Muscle of Obese Sheep at Late Gestation

(2009) Xu Yan et al.   ENDOCRINOLOGY

Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene

(2009) Qi Fu et al.   FASEB JOURNAL

CpG islands - ‘A rough guide’

(2009) Robert S. Illingworth et al.   FEBS LETTERS

Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression

(2009) Kimberley D. Bruce et al.   HEPATOLOGY

Adipocyte Apoptosis, a Link between Obesity, Insulin Resistance, and Hepatic Steatosis

(2009) Naim Alkhouri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early Life Origins of Obesity: Role of Hypothalamic Programming

(2009) Sebastien G Bouret   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies

(2009) Rocio G Urdinguio et al.   LANCET NEUROLOGY

Analysis of transcriptome and metabolome profiles alterations in fatty liver induced by high-fat diet in rat

(2009) Zuoquan Xie et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Epigenetic mechanisms that underpin metabolic and cardiovascular diseases

(2009) Peter D. Gluckman et al.   Nature Reviews Endocrinology

Pregnancy and Obesity

(2009) Yariv Yogev et al.   OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA

Gestational Protein Restriction in Mice Has Pronounced Effects on Gene Expression in Newborn Offspring's Liver and Skeletal Muscle; Protective Effect of Taurine

(2009) Ole Hartvig Mortensen et al.   PEDIATRIC RESEARCH

Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

(2009) Mira M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PPARγ activation in adipocytes is sufficient for systemic insulin sensitization

(2009) Shigeki Sugii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Importance of methyl donors during reproduction

(2008) Steven H Zeisel   AMERICAN JOURNAL OF CLINICAL NUTRITION

Pharmacological activation of LXR in utero directly influences ABC transporter expression and function in mice but does not affect adult cholesterol metabolism

(2008) E. M. E. van Straten et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Phosphorylation of IRS proteins, insulin action, and insulin resistance

(2008) Sigalit Boura-Halfon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Histones: Annotating Chromatin

(2008) Eric I. Campos et al.   Annual Review of Genetics

Role of histone modifications in defining chromatin structure and function

(2008) Kathy A. Gelato et al.   BIOLOGICAL CHEMISTRY

Managing Preexisting Diabetes for Pregnancy: Summary of evidence and consensus recommendations for care

(2008) J. L. Kitzmiller et al.   DIABETES CARE

Maternal Lipids as Strong Determinants of Fetal Environment and Growth in Pregnancies With Gestational Diabetes Mellitus

(2008) U. M. Schaefer-Graf et al.   DIABETES CARE

Effects of high-fat diet exposure during fetal life on type 2 diabetes development in the progeny

(2008) Donatella Gniuli et al.   JOURNAL OF LIPID RESEARCH

Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome

(2008) Kjersti M Aagaard-Tillery et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Maternal High-Fat Diet and Fetal Programming: Increased Proliferation of Hypothalamic Peptide-Producing Neurons That Increase Risk for Overeating and Obesity

(2008) G.-Q. Chang et al.   JOURNAL OF NEUROSCIENCE

AMP-activated protein kinase signalling pathways are down regulated and skeletal muscle development impaired in fetuses of obese, over-nourished sheep

(2008) Mei J. Zhu et al.   JOURNAL OF PHYSIOLOGY-LONDON

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

(2008) Roberta Benetti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Hyperglycemia and Adverse Pregnancy Outcomes

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Epigenetic Influences on Food Intake and Physical Activity Level: Review of Animal Studies

(2008) Barry E. Levin   Obesity

Obesity in Pregnancy Stimulates Macrophage Accumulation and Inflammation in the Placenta

(2008) J.C. Challier et al.   PLACENTA

Transport of fatty acids across the human placenta: A review

(2008) A DUTTAROY   PROGRESS IN LIPID RESEARCH

A Novel CpG Island Set Identifies Tissue-Specific Methylation at Developmental Gene Loci

(2008) Robert Illingworth et al.   PLOS BIOLOGY

Maternal supply of omega-3 polyunsaturated fatty acids alter mechanisms involved in oocyte and early embryo development in the mouse

(2007) Sarah L. Wakefield et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM