Olprinone and colforsin daropate alleviate septic lung inflammation and apoptosis through CREB-independent activation of the Akt pathway

Insights Into Sepsis Therapeutic Design Based on the Apoptotic Death Pathway

(2010) Yuichi Hattori et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Successful Treatment of Acute Lung Injury with Pitavastatin in Septic Mice: Potential Role of Glucocorticoid Receptor Expression in Alveolar Macrophages

(2010) K.-i. Takano et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Silencing of Fas-associated Death Domain Protects Mice from Septic Lung Inflammation and Apoptosis

(2009) Naoyuki Matsuda et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function

(2009) Maria Grandoch et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nuclear factor-κB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis*

(2009) Naoyuki Matsuda et al.   CRITICAL CARE MEDICINE

Acute Lung Injury:Apoptosis and Signaling Mechanisms

(2009) Mani Chopra et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Up-Regulation of Histamine H4 Receptors Contributes to Splenic Apoptosis in Septic Mice: Counteraction of the Antiapoptotic Action of Nuclear Factor- B

(2009) N. Matsuda et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Modulation of glucocorticoid receptor expression, inflammation, and cell apoptosis in septic guinea pig lungs using methylprednisolone

(2008) Koki Kamiyama et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Neuronal AKAP150 coordinates PKA and Epac-mediated PKB/Akt phosphorylation

(2008) Ingrid M. Nijholt et al.   CELLULAR SIGNALLING

Olprinone decreases elevated concentrations of cytokine-induced neutrophil chemoattractant-1 in septic rats

(2008) Hiroshi Miyakawa et al.   Journal of Anesthesia

A Novel Epac-Rap-PP2A Signaling Module Controls cAMP-dependent Akt Regulation

(2008) Kyoungja Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulating gene transcription in response to cyclic AMP elevation

(2007) William A. Sands et al.   CELLULAR SIGNALLING

Pretreatment with olprinone hydrochloride, a phosphodiesterase III inhibitor, attenuates lipopolysaccharide-induced lung injury via an anti-inflammatory effect

(2007) Terumoto Koike et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS