Low intrinsic exercise capacity in rats predisposes to age-dependent cardiac remodeling independent of macrovascular function

Overweight female rats selectively breed for low aerobic capacity exhibit increased myocardial fibrosis and diastolic dysfunction

(2012) Vincent G. DeMarco et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Enhanced phosphoinositide 3-kinase(p110α) activity prevents diabetes-induced cardiomyopathy and superoxide generation in a mouse model of diabetes

(2012) R. H. Ritchie et al.   DIABETOLOGIA

Coenzyme Q10 attenuates diastolic dysfunction, cardiomyocyte hypertrophy and cardiac fibrosis in the db/db mouse model of type 2 diabetes

(2012) K. Huynh et al.   DIABETOLOGIA

Divergent skeletal muscle respiratory capacities in rats artificially selected for high and low running ability: a role for Nor1?

(2012) Erin J. Stephenson et al.   JOURNAL OF APPLIED PHYSIOLOGY

Optical Coherence Tomography in Parkinsonian Syndromes

(2012) Philipp Albrecht et al.   PLoS One

Low intrinsic running capacity is associated with reduced skeletal muscle substrate oxidation and lower mitochondrial content in white skeletal muscle

(2011) Donato A. Rivas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Intrinsic Aerobic Capacity Sets a Divide for Aging and Longevity

(2011) Lauren Gerard Koch et al.   CIRCULATION RESEARCH

Myocardial autophagy activation and suppressed survival signaling is associated with insulin resistance in fructose-fed mice

(2011) Kimberley M. Mellor et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity

(2011) Jatin G. Burniston et al.   PROTEOMICS

Exercise training reverses impaired skeletal muscle metabolism induced by artificial selection for low aerobic capacity

(2010) Sarah J. Lessard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Lower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity

(2010) Constance Tweedie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Impairment of both nitric oxide-mediated and EDHF-type relaxation in small mesenteric arteries from rats with streptozotocin-induced diabetes

(2010) CH Leo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cardiac-Specific IGF-1 Receptor Transgenic Expression Protects Against Cardiac Fibrosis and Diastolic Dysfunction in a Mouse Model of Diabetic Cardiomyopathy

(2010) K. Huynh et al.   DIABETES

Diastolic dysfunction in diabetes and the metabolic syndrome: promising potential for diagnosis and prognosis

(2010) H. von Bibra et al.   DIABETOLOGIA

Impaired Glucose Tolerance and Insulin Resistance in Heart Failure: Underrecognized and Undertreated?

(2010) Mamas A. Mamas et al.   JOURNAL OF CARDIAC FAILURE

The effect of exercise training on transverse tubules in normal, remodeled, and reverse remodeled hearts

(2010) Ole J. Kemi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Transfer of nitric oxide by blood from upstream to downstream resistance vessels causes microvascular dilation

(2009) H. G. Bohlen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Reactive oxygen species and insulin-resistant cardiomyopathy

(2009) Kimberley M Mellor et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Impaired Skeletal Muscle β-Adrenergic Activation and Lipolysis Are Associated with Whole-Body Insulin Resistance in Rats Bred for Low Intrinsic Exercise Capacity

(2009) Sarah J. Lessard et al.   ENDOCRINOLOGY

Evidence for a Causal Role of Oxidative Stress in the Myocardial Complications of Insulin Resistance

(2009) Rebecca H. Ritchie   Heart Lung and Circulation

High-fructose diet elevates myocardial superoxide generation in mice in the absence of cardiac hypertrophy

(2009) Kimberley Mellor et al.   NUTRITION

Exploiting cGMP-based therapies for the prevention of left ventricular hypertrophy: NO• and beyond

(2009) Rebecca H. Ritchie et al.   PHARMACOLOGY & THERAPEUTICS

In vivo regulation of endothelium-dependent vasodilation in the rat renal circulation and the effect of streptozotocin-induced diabetes

(2008) Amanda J. Edgley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Endothelium-derived hyperpolarizing factor in vascular physiology and cardiovascular disease

(2008) Leanid Luksha et al.   ATHEROSCLEROSIS

Reduced EDHF responses and connexin activity in mesenteric arteries from the insulin-resistant obese Zucker rat

(2008) E. J. Young et al.   DIABETOLOGIA

Aerobic capacity-dependent differences in cardiac gene expression

(2008) Anja Bye et al.   PHYSIOLOGICAL GENOMICS

Impaired small-conductance Ca2+-activated K+ channel-dependent EDHF responses in Type II diabetic ZDF rats

(2006) Matthew P Burnham et al.   BRITISH JOURNAL OF PHARMACOLOGY