Lower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity

Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers

(2010) Martin Picard et al.   AGING CELL

Hydrogen peroxide efflux from muscle mitochondria underestimates matrix superoxide production - a correction using glutathione depletion

(2010) Jason R. Treberg et al.   FEBS Journal

Low Aerobic Capacity and High-Fat Diet Contribute to Oxidative Stress and IRS-1 Degradation in the Kidney

(2009) E. Matthew Morris et al.   AMERICAN JOURNAL OF NEPHROLOGY

Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis

(2009) Kai Hartwig et al.   Genes and Nutrition

Signals of recent positive selection in a worldwide sample of human populations

(2009) J. K. Pickrell et al.   GENOME RESEARCH

Reversal of the Mitochondrial Phenotype and Slow Development of Oxidative Biomarkers of Aging in Long-livedMclk1+/−Mice

(2009) Jérôme Lapointe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury

(2009) John P. Thyfault et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oxidative stress and metabolic syndrome

(2009) Christian K. Roberts et al.   LIFE SCIENCES

A novel component of the metabolic syndrome: The oxidative stress

(2009) E. Hopps et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

CK2 Is the Regulator of SIRT1 Substrate-Binding Affinity, Deacetylase Activity and Cellular Response to DNA-Damage

(2009) Hyeog Kang et al.   PLoS One

Antioxidants prevent health-promoting effects of physical exercise in humans

(2009) M. Ristow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans

(2009) Jeremy M. Van Raamsdonk et al.   PLoS Genetics

High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates

(2008) Florian L. Muller et al.   BIOCHEMICAL JOURNAL

Role of Mitochondrial Dysfunction in Insulin Resistance

(2008) Jeong-a Kim et al.   CIRCULATION RESEARCH

Peripheral oxygen transport and utilization in rats following continued selective breeding for endurance running capacity

(2008) Richard A. Howlett et al.   JOURNAL OF APPLIED PHYSIOLOGY

Early Mitochondrial Dysfunction in Long-livedMclk1+/-Mice

(2008) Jérôme Lapointe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and nuclear factor κB activation

(2008) Susan V. Brooks et al.   JOURNAL OF PHYSIOLOGY-LONDON

Aerobic capacity-dependent differences in cardiac gene expression

(2008) Anja Bye et al.   PHYSIOLOGICAL GENOMICS

Gene expression profiling of skeletal muscle in exercise-trained and sedentary rats with inborn high and low VO2max

(2008) Anja Bye et al.   PHYSIOLOGICAL GENOMICS

Increased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individuals

(2008) D. E. Befroy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sirt1 protects against high-fat diet-induced metabolic damage

(2008) P. T. Pfluger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal protein restriction leads to early life alterations in the expression of key molecules involved in the aging process in rat offspring

(2007) Malgorzata S. Martin-Gronert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Systemic adaptation to oxidative challenge induced by regular exercise

(2007) Zsolt Radak et al.   FREE RADICAL BIOLOGY AND MEDICINE

Aerobic metabolism underlies complexity and capacity

(2007) Lauren G. Koch et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exercise Training Promotes SIRT1 Activity in Aged Rats

(2007) Nicola Ferrara et al.   REJUVENATION RESEARCH