Endothelium-dependent control of cerebrovascular functions through age: exercise for healthy cerebrovascular aging

Postnatal exposure to voluntary exercise but not the antioxidant catechin protects the vasculature after a switch to an atherogenic environment in middle-age mice

(2013) Francois Leblond et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Evolutionary aspects of human exercise—Born to run purposefully

(2012) Mark P. Mattson   AGEING RESEARCH REVIEWS

Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr−/−:hApoB+/+ mice and improves cerebral blood flow

(2012) Virginie Bolduc et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

A turning point for Alzheimer's disease?

(2012) Jack C. de la Torre   BIOFACTORS

FOXOs and Sirtuins in Vascular Growth, Maintenance, and Aging

(2012) Mark F. Oellerich et al.   CIRCULATION RESEARCH

Running throughout middle-age improves memory function, hippocampal neurogenesis, and BDNF levels in female C57BL/6J mice

(2012) Michael W. Marlatt et al.   Developmental Neurobiology

Impact of resting heart rate on mortality, disability and cognitive decline in patients after ischaemic stroke

(2012) M. Bohm et al.   EUROPEAN HEART JOURNAL

α1-Adrenergic receptor control of the cerebral vasculature in humans at rest and during exercise

(2012) Sushmita Purkayastha et al.   EXPERIMENTAL PHYSIOLOGY

Influence of exercise training on ischemic brain injury in type 1 diabetic rats

(2012) Denise M. Arrick et al.   JOURNAL OF APPLIED PHYSIOLOGY

Brain Energy Metabolism and Blood Flow Differences in Healthy Aging

(2012) Joel Aanerud et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Contribution of Flow-Dependent Vasomotor Mechanisms to the Autoregulation of Cerebral Blood Flow

(2012) Akos Koller et al.   JOURNAL OF VASCULAR RESEARCH

Exercise and longevity

(2012) Vincent Gremeaux et al.   MATURITAS

Are sirtuins viable targets for improving healthspan and lifespan?

(2012) Joseph A. Baur et al.   NATURE REVIEWS DRUG DISCOVERY

Cerebral hemodynamics and cognitive impairment: Baseline data from the RECON trial

(2012) R. S. Marshall et al.   NEUROLOGY

Heart rate-associated mechanical stress impairs carotid but not cerebral artery compliance in dyslipidemic atherosclerotic mice

(2011) Virginie Bolduc et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Protecting against vascular disease in brain

(2011) Frank M. Faraci   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Association Between Decline in Physical Functioning and Atrophy of Medial Temporal Areas in Community-Dwelling Older Adults With Amnestic and Nonamnestic Mild Cognitive Impairment

(2011) Hyuma Makizako et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Aging Causes Collateral Rarefaction and Increased Severity of Ischemic Injury in Multiple Tissues

(2011) James E. Faber et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of Gi/o-Src kinase-PI3K/Akt pathway and caveolin-1 in β2-adrenoceptor coupling to endothelial NO synthase in mouse pulmonary artery

(2011) Sébastien Banquet et al.   CELLULAR SIGNALLING

The effect of phenylephrine on arterial and venous cerebral blood flow in healthy subjects

(2011) Shigehiko Ogoh et al.   CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING

Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

Exercise-induced oxidative-nitrosative stress is associated with impaired dynamic cerebral autoregulation and blood-brain barrier leakage

(2011) Damian M. Bailey et al.   EXPERIMENTAL PHYSIOLOGY

Exercise, brain, and cognition across the life span

(2011) Michelle W. Voss et al.   JOURNAL OF APPLIED PHYSIOLOGY

Isolated Human and Rat Cerebral Arteries Constrict to Increases in Flow: Role of 20-HETE and TP Receptors

(2011) Peter Toth et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Survival benefit associated with low-level physical activity

(2011) Anil Nigam et al.   LANCET

Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study

(2011) Chi Pang Wen et al.   LANCET

Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging

(2011) J. Eric Ahlskog et al.   MAYO CLINIC PROCEEDINGS

Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: Involvement of hippocampal plasticity via AKT, CREB and BDNF signaling

(2011) Aderbal S. Aguiar et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Up-regulation of thromboxane A2 impairs cerebrovascular eNOS function in aging atherosclerotic mice

(2011) Annick Drouin et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Age-related changes in endothelial function and blood flow regulation

(2011) Noboru Toda   PHARMACOLOGY & THERAPEUTICS

The Influence of Physiological Aging and Atrophy on Brain Viscoelastic Properties in Humans

(2011) Ingolf Sack et al.   PLoS One

Blood–Brain Barrier Breakdown in Acute and Chronic Cerebrovascular Disease

(2011) Yi Yang et al.   STROKE

Heart Rate Contributes to the Vascular Effects of Chronic Mental Stress

(2011) Florian Custodis et al.   STROKE

Vascular risk factor detection and control may prevent Alzheimer's disease

(2010) Jack C. de la Torre   AGEING RESEARCH REVIEWS

Catechin treatment improves cerebrovascular flow-mediated dilation and learning abilities in atherosclerotic mice

(2010) Annick Drouin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Physical Exercise, Aging, and Mild Cognitive Impairment

(2010) Yonas E. Geda et al.   ARCHIVES OF NEUROLOGY

Cardiovascular Effects of Exercise Training

(2010) Stephan Gielen et al.   CIRCULATION

Exercise Capacity and Mortality in Older Men

(2010) Peter Kokkinos et al.   CIRCULATION

Cardiovascular Effects of 1 Year of Progressive and Vigorous Exercise Training in Previously Sedentary Individuals Older Than 65 Years of Age

(2010) Naoki Fujimoto et al.   CIRCULATION

Endothelial Nitric Oxide Modulates Expression and Processing of Amyloid Precursor Protein

(2010) Susan A. Austin et al.   CIRCULATION RESEARCH

Current role of beta-blockers in the treatment of hypertension

(2010) Wilbert S Aronow   EXPERT OPINION ON PHARMACOTHERAPY

Physical Frailty Is Associated with Incident Mild Cognitive Impairment in Community-Based Older Persons

(2010) Patricia A. Boyle et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Asymmetric dimethylarginine (ADMA) as a possible risk marker for ischemic stroke

(2010) Yasuhiro Nishiyama et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study

(2010) Martin J O'Donnell et al.   LANCET

Beta-Adrenergic Stimulation Contributes to Maintenance of Endothelial Barrier Functions Under Baseline Conditions

(2010) VOLKER SPINDLER et al.   MICROCIRCULATION

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Resuscitating the heart but losing the brain: Brain atrophy in the aftermath of cardiac arrest

(2010) A. Horstmann et al.   NEUROLOGY

Review: Cerebral microvascular pathology in ageing and neurodegeneration

(2010) W. R. Brown et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Decrease in Asymmetrical Dimethylarginine, an Endogenous Nitric Oxide Synthase Inhibitor, in Cerebrospinal Fluid during Elderly Aging and in Patients with Sporadic Form of Amyotrophic Lateral Sclerosis

(2010) Chiaki Isobe et al.   NEUROSIGNALS

Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain

(2010) F. Fernandez-Klett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Mouse Model Characterizing Features of Vascular Dementia With Hippocampal Atrophy

(2010) Keiko Nishio et al.   STROKE

Pumps, Aqueducts, and Drought Management

(2010) Randolph S. Marshall et al.   STROKE

The Cardiovascular Continuum extended: Aging effects on the aorta and microvasculature

(2010) Michael F O'Rourke et al.   VASCULAR MEDICINE

NO production and eNOS phosphorylation induced by epinephrine through the activation of β-adrenoceptors

(2009) Xavier F. Figueroa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Role of oxidative stress and AT1 receptors in cerebral vascular dysfunction with aging

(2009) Mary L. Modrick et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Association of Muscle Strength With the Risk of Alzheimer Disease and the Rate of Cognitive Decline in Community-Dwelling Older Persons

(2009) Patricia A. Boyle et al.   ARCHIVES OF NEUROLOGY

Resting cerebral blood flow, attention, and aging

(2009) Katja Bertsch et al.   BRAIN RESEARCH

Vascular endothelial ageing, heartbeat after heartbeat

(2009) E. Thorin et al.   CARDIOVASCULAR RESEARCH

Vascular Mechanobiology

(2009) Joji Ando et al.   CIRCULATION JOURNAL

Long-term changes in dynamic cerebral autoregulation: a 10 years follow up study

(2009) Fiona G. Brodie et al.   CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING

FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer’s disease

(2009) Lisa Mosconi et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Is exercise training an effective therapy targeting endothelial dysfunction and vascular wall inflammation?

(2009) Fernando Ribeiro et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Jugular venous overflow of noradrenaline from the brain: a neurochemical indicator of cerebrovascular sympathetic nerve activity in humans

(2009) David A. Mitchell et al.   JOURNAL OF PHYSIOLOGY-LONDON

The progression of cognitive deterioration and regional cerebral blood flow patterns in Alzheimer's disease: A longitudinal SPECT study

(2009) Haruo Hanyu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Small Artery Remodeling: Current Concepts and Questions

(2009) Jeroen van den Akker et al.   JOURNAL OF VASCULAR RESEARCH

Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery

(2009) Muge Yemisci et al.   NATURE MEDICINE

Propranolol adrenergic blockade inhibits human brain endothelial cells tubulogenesis and matrix metalloproteinase-9 secretion

(2009) Borhane Annabi et al.   PHARMACOLOGICAL RESEARCH

The Plastic Nature of the Vascular Wall: A Continuum of Remodeling Events Contributing to Control of Arteriolar Diameter and Structure

(2009) Luis A. Martinez-Lemus et al.   PHYSIOLOGY

Association of Plasma ADMA Levels With MRI Markers of Vascular Brain Injury

(2009) Aleksandra Pikula et al.   STROKE

Effect of Aging on Elastin Functionality in Human Cerebral Arteries

(2009) Edouard Fonck et al.   STROKE

Flow-Induced Dilation Is Mediated by Akt-Dependent Activation of Endothelial Nitric Oxide Synthase-Derived Hydrogen Peroxide in Mouse Cerebral Arteries

(2009) Annick Drouin et al.   STROKE

Astrocytes and the regulation of cerebral blood flow

(2009) Raymond C. Koehler et al.   TRENDS IN NEUROSCIENCES

Reduced Disability and Mortality Among Aging Runners

(2008) Eliza F. Chakravarty   ARCHIVES OF INTERNAL MEDICINE

Hypertension and Cerebrovascular Dysfunction

(2008) Costantino Iadecola et al.   Cell Metabolism

Effect of Physical Activity on Cognitive Function in Older Adults at Risk for Alzheimer Disease

(2008) Nicola T. Lautenschlager et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Cerebral Autoregulation: An Overview of Current Concepts and Methodology with Special Focus on the Elderly

(2008) Arenda HEA van Beek et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Downhill training upregulates mice hippocampal and striatal brain-derived neurotrophic factor levels

(2008) Aderbal S. Aguiar et al.   JOURNAL OF NEURAL TRANSMISSION

Mechanism of ATP-Induced Local and Conducted Vasomotor Responses in Isolated Rat Cerebral Penetrating Arterioles

(2008) Hans H. Dietrich et al.   JOURNAL OF VASCULAR RESEARCH

Global burden of blood-pressure-related disease, 2001

(2008) Carlene MM Lawes et al.   LANCET

Heart rate as a prognostic risk factor in patients with coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a subgroup analysis of a randomised controlled trial

(2008) Kim Fox et al.   LANCET

Age-Related Alterations in Reactivity of Cerebral Arterioles: Role of Oxidative Stress

(2008) William G. Mayhan et al.   MICROCIRCULATION

Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6

(2008) Bente K. Pedersen et al.   PHYSIOLOGICAL REVIEWS

Catecholamines and the Effects of Exercise, Training and Gender

(2008) Hassane Zouhal et al.   SPORTS MEDICINE

Threats to the Mind: Aging, Amyloid, and Hypertension

(2008) C. Iadecola et al.   STROKE

The role of oxidative stress and NADPH oxidase in cerebrovascular disease

(2008) Sophocles Chrissobolis et al.   TRENDS IN MOLECULAR MEDICINE

Be smart, exercise your heart: exercise effects on brain and cognition

(2007) Charles H. Hillman et al.   NATURE REVIEWS NEUROSCIENCE

Overexpression of Dimethylarginine Dimethylaminohydrolase Inhibits Asymmetric Dimethylarginine–Induced Endothelial Dysfunction in the Cerebral Circulation

(2007) Hayan Dayoub et al.   STROKE