Novel role of p66Shc in ROS-dependent VEGF signaling and angiogenesis in endothelial cells

P66SHC and Ageing: ROS and TOR?

(2016) Giovambattista Pani   Aging-US

Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species

(2011) Youxue Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Localized cysteine sulfenic acid formation by vascular endothelial growth factor: role in endothelial cell migration and angiogenesis

(2011) Nihal Kaplan et al.   FREE RADICAL RESEARCH

At the crossroads of longevity and metabolism: the metabolic syndrome and lifespan determinant pathways

(2010) Gian Paolo Fadini et al.   AGING CELL

Extracellular SOD-Derived H2O2 Promotes VEGF Signaling in Caveolae/Lipid Rafts and Post-Ischemic Angiogenesis in Mice

(2010) Jin Oshikawa et al.   PLoS One

Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance

(2010) S. C. Ranieri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Downstream Targets and Intracellular Compartmentalization in Nox Signaling

(2009) Kai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox2-Containing NADPH Oxidase Deficiency Confers Protection From Hindlimb Ischemia in Conditions of Increased Oxidative Stress

(2009) Paola Haddad et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The cardioprotective effects elicited by p66Shc ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury

(2009) Andrea Carpi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

p66Shc Links α 1 -Adrenergic Receptors to a Reactive Oxygen Species-Dependent AKT-FOXO3A Phosphorylation Pathway in Cardiomyocytes

(2009) Jianfen Guo et al.   CIRCULATION RESEARCH

Decreased Superoxide Production in Macrophages of Long-lived p66Shc Knock-out Mice

(2009) Alexey A. Tomilov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The adaptor protein p66shc is a positive regulator in the angiogenic response induced by hypoxic T cells

(2009) A. Naldini et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Compartmentalization of Redox Signaling Through NADPH Oxidase–Derived ROS

(2008) Masuko Ushio-Fukai   ANTIOXIDANTS & REDOX SIGNALING

Role of Nox2-Based NADPH Oxidase in Bone Marrow and Progenitor Cell Function Involved in Neovascularization Induced by Hindlimb Ischemia

(2008) Norifumi Urao et al.   CIRCULATION RESEARCH

p66shcInhibits Pro-survival Epidermal Growth Factor Receptor/ERK Signaling during Severe Oxidative Stress in Mouse Renal Proximal Tubule Cells

(2008) Istvan Arany et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelin-1 Couples βPix to p66Shc: Role of βPix in Cell Proliferation through FOXO3a Phosphorylation and p27kip1 Down-Regulation Independently of Akt

(2008) Ahmed Chahdi et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondrial redox signaling by p66Shc is involved in regulating androgenic growth stimulation of human prostate cancer cells

(2008) S Veeramani et al.   ONCOGENE

Final Common Molecular Pathways of Aging and Cardiovascular Disease

(2007) Francesco Cosentino et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY