Trypsin impaired epithelial barrier function and induced IL-8 secretion through basolateral PAR-2: a lesson from a stratified squamous epithelial model

Bile salts disrupt human esophageal squamous epithelial barrier function by modulating tight junction proteins

(2012) Xin Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Subepithelial trypsin induces enteric nerve-mediated anion secretion by activating proteinase-activated receptor 1 in the mouse cecum

(2012) Osamu Ikehara et al.   Journal of Physiological Sciences

Role of E-cadherin in the Pathogenesis of Gastroesophageal Reflux Disease

(2011) Biljana Jovov et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Establishment of esophageal-like non-keratinized stratified epithelium using normal human bronchial epithelial cells

(2011) Tadayuki Oshima et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins

(2011) Xin Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Protease-activated receptor 2 signaling in inflammation

(2011) Andrea S. Rothmeier et al.   Seminars in Immunopathology

Editorial: Bringing GERD Management up to PAR-2

(2010) Rhonda F Souza   AMERICAN JOURNAL OF GASTROENTEROLOGY

Proteinase-Activated Receptor-2 in the Pathogenesis of Gastroesophageal Reflux Disease

(2010) Arne Kandulski et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Diagnosis of Gastroesophageal Reflux Disease

(2010) Brian E. Lacy et al.   AMERICAN JOURNAL OF MEDICINE

Hydrolysis of β-lactoglobulin by trypsin under acidic pH and analysis of the hydrolysates with MALDI–TOF–MS/MS

(2010) Seronei Chelulei Cheison et al.   FOOD CHEMISTRY

Interleukin-1Beta and Interleukin-8 Expression Correlate with the Histomorphological Changes in Esophageal Mucosa of Patients with Erosive and Non-Erosive Reflux Disease

(2009) Klaus Mönkemüller et al.   DIGESTION

Gastroesophageal Reflux Might Cause Esophagitis Through a Cytokine-Mediated Mechanism Rather Than Caustic Acid Injury

(2009) Rhonda F. Souza et al.   GASTROENTEROLOGY

Expression of protease-activated-receptor 2 (PAR-2) in human esophageal mucosa

(2009) Kamuran Inci et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Prevalence of bile reflux in gastroesophageal reflux disease patients not responsive to proton pump inhibitors

(2009) Luigi Monaco et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Systematic review: the epidemiology of gastro-oesophageal reflux disease in primary care, using the UK General Practice Research Database

(2008) H. EL-SERAG et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-κB

(2008) Parvaneh Rafiee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Basic and Translational Research on Proteinase-Activated Receptors: Implication of Proteinase/Proteinase-Activated Receptor in Gastrointestinal Inflammation

(2008) Norimasa Yoshida et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Protease-activated receptor 2 and gut permeability: a review

(2008) l. bueno et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Gastrointestinal roles for proteinase-activated receptors in health and disease

(2007) A Kawabata et al.   BRITISH JOURNAL OF PHARMACOLOGY