Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet

Weight and Metabolic Outcomes After 2 Years on a Low-Carbohydrate Versus Low-Fat Diet

(2013) Gary D. Foster   ANNALS OF INTERNAL MEDICINE

Linking the inflammasome to obesity-related disease

(2011) Tiffany Horng et al.   NATURE MEDICINE

Regulation of glucose homeostasis through a XBP-1–FoxO1 interaction

(2011) Yingjiang Zhou et al.   NATURE MEDICINE

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain

(2010) François R. Jornayvaz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein

(2010) Maximilian Bielohuby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

(2010) Sarah Hummasti et al.   CIRCULATION RESEARCH

Increased Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease

(2010) Jody Dushay et al.   GASTROENTEROLOGY

Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites

(2010) Brent A. Neuschwander-Tetri   HEPATOLOGY

Prevalence and Trends in Obesity Among US Adults, 1999-2008

(2010) Katherine M. Flegal   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Adaptation of Myocardial Substrate Metabolism to a Ketogenic Nutrient Environment

(2010) Anna E. Wentz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibroblast growth factor 21 as a biomarker for NAFLD: Integrating pathobiology into clinical practice

(2010) Gareth Morris-Stiff et al.   JOURNAL OF HEPATOLOGY

Autophagy: assays and artifacts

(2010) Sandra Barth et al.   JOURNAL OF PATHOLOGY

Pathology of nonalcoholic fatty liver disease

(2010) Elizabeth M. Brunt   Nature Reviews Gastroenterology & Hepatology

A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss

(2009) Michael K. Badman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Trans fat feeding results in higher serum alanine aminotransferase and increased insulin resistance compared with a standard murine high-fat diet

(2009) Sean W. P. Koppe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

As a Matter of Fat

(2009) Rita T. Brookheart et al.   Cell Metabolism

Pioglitazone Reduces ER Stress in the Liver: Direct Monitoring of in vivo ER Stress Using ER Stress-activated Indicator Transgenic Mice

(2009) Kazutomi YOSHIUCHI et al.   ENDOCRINE JOURNAL

Fibroblast Growth Factor 21-Deficient Mice Demonstrate Impaired Adaptation to Ketosis

(2009) Michael K. Badman et al.   ENDOCRINOLOGY

Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications

(2009) Elisa Fabbrini et al.   HEPATOLOGY

Dynamic and differential regulation of proteins that coat lipid droplets infatty liver dystrophicmice

(2009) Angela M. Hall et al.   JOURNAL OF LIPID RESEARCH

PGC-1α negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erbα axis

(2009) Jennifer L. Estall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity

(2009) E. Fabbrini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FGF21 induces PGC-1  and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

(2009) M. J. Potthoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation

(2009) P. A. Crawford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies

(2008) Marwan Maalouf et al.   BRAIN RESEARCH REVIEWS

Hepatic Steatosis in Leptin-Deficient Mice Is Promoted by the PPARγ Target Gene Fsp27

(2008) Kimihiko Matsusue et al.   Cell Metabolism

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

(2008) D. Thomas Rutkowski et al.   DEVELOPMENTAL CELL

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

(2008) J. Xu et al.   DIABETES

Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet

(2008) Iris Shai et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1

(2008) A.-H. Lee et al.   SCIENCE

Restricted-Carbohydrate Diets in Patients with Type 2 Diabetes: A Meta-Analysis

(2007) Julienne K. Kirk et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION