Caveolin-1/PTRF upregulation constitutes a mechanism for mediating p53-induced cellular senescence: implications for evidence-based therapy of delayed wound healing in diabetes

Cellular senescence controls fibrosis in wound healing

(2016) Joon-Il Jun et al.   Aging-US

p38 MAPK inhibition reduces diabetes-induced impairment of wound healing

(2016) Linda Higgins   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes

(2012) M. S. Bitar et al.   Disease Models & Mechanisms

Caveolin-1 Inhibits Expression of Antioxidant Enzymes through Direct Interaction with Nuclear Erythroid 2 p45-related Factor-2 (Nrf2)

(2012) Wen Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A defect in Nrf2 signaling constitutes a mechanism for cellular stress hypersensitivity in a genetic rat model of type 2 diabetes

(2011) Milad S. Bitar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Caveolar vesicles generate DNA damage and perpetuate cellular aging

(2011) Keith Wheaton   CELL RESEARCH

Regulation of cellular senescence by the essential caveolar component PTRF/Cavin-1

(2011) Lin Bai et al.   CELL RESEARCH

Polymerase I and Transcript Release Factor (PTRF)/Cavin-1 Is a Novel Regulator of Stress-induced Premature Senescence

(2011) Daniela Volonte et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caveolin-1, cellular senescence and age-related diseases

(2011) Huafei Zou et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Impaired TGF-β signaling and a defect in resolution of inflammation contribute to delayed wound healing in a female rat model of type 2 diabetes

(2011) Fahd Al-Mulla et al.   Molecular BioSystems

Diabetic lower extremity wounds: the rationale for growth factors-based infiltration treatment

(2011) Jorge Berlanga-Acosta   International Wound Journal

Inflammation and apoptosis in aortic tissues of aged type II diabetes: Amelioration with α-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism

(2010) Milad S. Bitar et al.   LIFE SCIENCES

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(2010) Ji Rhim et al.   MOLECULAR MEDICINE

Caveolin-1 Regulates the Antagonistic Pleiotropic Properties of Cellular Senescence through a Novel Mdm2/p53-Mediated Pathway

(2009) J. N. Bartholomew et al.   CANCER RESEARCH

Angiogenic growth factors inhibit chondrocyte ageing in osteoarthritis: potential involvement of catabolic stress-induced overexpression of caveolin-1 in cellular ageing

(2009) Kazuo YUDOH et al.   International Journal of Rheumatic Diseases

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Nitric oxide elicits functional MMP-13 protein-tyrosine nitration during wound repair

(2008) Tania R. Lizarbe et al.   FASEB JOURNAL

Increased abundance of cytoplasmic and nuclear caveolin 1 in human diploid fibroblasts in H2O2-induced premature senescence and interplay with p38αMAPK

(2008) Aline Chrétien et al.   FEBS LETTERS

Oxidative Stress and “Senescent” Fibroblasts in Non-Healing Wounds as Potential Therapeutic Targets

(2008) Richard A.F. Clark   JOURNAL OF INVESTIGATIVE DERMATOLOGY