Mitochondrial uncoupling in skeletal muscle by UCP1 augments energy expenditure and glutathione content while mitigating ROS production

Glutaredoxin-2 Is Required to Control Proton Leak through Uncoupling Protein-3

(2013) Ryan J. Mailloux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Fatty-Acid-Dependent UCP1 Uncoupling in Brown Fat Mitochondria

(2012) Andriy Fedorenko et al.   CELL

Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity

(2012) Ana Ortega-Molina et al.   Cell Metabolism

Calorie restriction in mice overexpressing UCP3: Evidence that prior mitochondrial uncoupling alters response

(2012) Carmen Estey et al.   EXPERIMENTAL GERONTOLOGY

Uncoupling protein 1 dependent reactive oxygen species production by thymus mitochondria

(2012) Kieran J. Clarke et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Glutathionylation State of Uncoupling Protein-2 and the Control of Glucose-stimulated Insulin Secretion

(2012) Ryan J. Mailloux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Implications of nonshivering thermogenesis for energy balance regulation in humans

(2011) Wouter D. van Marken Lichtenbelt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hexokinase II acts through UCP3 to suppress mitochondrial reactive oxygen species production and maintain aerobic respiration

(2011) Ryan J. Mailloux et al.   BIOCHEMICAL JOURNAL

Brown adipose tissue mitochondria oxidizing fatty acids generate high levels of reactive oxygen species irrespective of the uncoupling protein-1 activity state

(2011) Peter Schönfeld et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Crucial yet divergent roles of mitochondrial redox state in skeletal muscle vs. brown adipose tissue energetics

(2011) Ryan J. Mailloux et al.   FASEB JOURNAL

Glutathionylation Acts as a Control Switch for Uncoupling Proteins UCP2 and UCP3

(2011) Ryan J. Mailloux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Age-Related Decrease in Cold-Activated Brown Adipose Tissue and Accumulation of Body Fat in Healthy Humans

(2011) Takeshi Yoneshiro et al.   Obesity

High Throughput Microplate Respiratory Measurements Using Minimal Quantities Of Isolated Mitochondria

(2011) George W. Rogers et al.   PLoS One

Using brown adipose tissue to treat obesity – the central issue

(2011) Andrew J. Whittle et al.   TRENDS IN MOLECULAR MEDICINE

Obesity-Related Quality-Adjusted Life Years Lost in the U.S. from 1993 to 2008

(2010) Haomiao Jia et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Mitochondrial proton and electron leaks

(2010) Martin Jastroch et al.   Essays in Biochemistry

Uncoupling Protein 1 Decreases Superoxide Production in Brown Adipose Tissue Mitochondria

(2010) Rebecca Oelkrug et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct skeletal muscle fiber characteristics and gene expression in diet-sensitive versus diet-resistant obesity

(2010) Martin F. Gerrits et al.   JOURNAL OF LIPID RESEARCH

UCP1 ectopically expressed in murine muscle displays native function and mitigates mitochondrial superoxide production

(2009) Susanne Keipert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria

(2009) Nadeene Parker et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

The on-off switches of the mitochondrial uncoupling proteins

(2009) Vian Azzu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Long-term high-fat feeding induces greater fat storage in mice lacking UCP3

(2008) Sheila R. Costford et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Efficiency of Cellular Energy Transduction and Its Implications for Obesity

(2008) Mary-Ellen Harper et al.   Annual Review of Nutrition

Mitochondrial ATP synthase levels in brown adipose tissue are governed by the c-Fo subunit P1 isoform

(2007) Tatiana V. Kramarova et al.   FASEB JOURNAL

Dissociation of obesity and insulin resistance in transgenic mice with skeletal muscle expression of uncoupling protein 1

(2007) Yvonne Katterle et al.   PHYSIOLOGICAL GENOMICS