Glutathionylation State of Uncoupling Protein-2 and the Control of Glucose-stimulated Insulin Secretion

Mitochondrial proticity and ROS signaling: lessons from the uncoupling proteins

(2012) Ryan J. Mailloux et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Linking mitochondrial bioenergetics to insulin resistance via redox biology

(2012) Kelsey H. Fisher-Wellman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mechanisms of Altered Redox Regulation in Neurodegenerative Diseases—Focus on S-Glutathionylation

(2011) Elizabeth A. Sabens Liedhegner et al.   ANTIOXIDANTS & REDOX SIGNALING

Posttranslational Modification of Cysteine in Redox Signaling and Oxidative Stress: Focus on S-Glutathionylation

(2011) John J. Mieyal et al.   ANTIOXIDANTS & REDOX SIGNALING

β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion

(2011) Christine A. Robson-Doucette et al.   DIABETES

Reversible and irreversible protein glutathionylation: biological and clinical aspects

(2011) Arthur JL Cooper et al.   Expert Opinion on Drug Metabolism & Toxicology

Crucial yet divergent roles of mitochondrial redox state in skeletal muscle vs. brown adipose tissue energetics

(2011) Ryan J. Mailloux et al.   FASEB JOURNAL

Uncoupling proteins and the control of mitochondrial reactive oxygen species production

(2011) Ryan J. Mailloux et al.   FREE RADICAL BIOLOGY AND MEDICINE

Glutathionylation Acts as a Control Switch for Uncoupling Proteins UCP2 and UCP3

(2011) Ryan J. Mailloux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of the Intracellular Redox State by Glucose Participates in the Insulin Secretion Mechanism

(2011) Eduardo Rebelato et al.   PLoS One

The level of menadione redox-cycling in pancreatic β-cells is proportional to the glucose concentration: Role of NADH and consequences for insulin secretion

(2011) Emma Heart et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Glucose Stimulation of Hypothalamic MCH Neurons Involves KATP Channels, Is Modulated by UCP2, and Regulates Peripheral Glucose Homeostasis

(2010) Dong Kong et al.   Cell Metabolism

Decreasing Txnip mRNA and Protein Levels in Pancreatic MIN6 Cells Reduces Reactive Oxygen Species and Restores Glucose Regulated Insulin Secretion

(2010) Sweta Rani et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Reactive oxygen species and uncoupling protein 2 in pancreatic β-cell function

(2010) J. Pi et al.   DIABETES OBESITY & METABOLISM

Glucose regulates enzymatic sources of mitochondrial NADPH in skeletal muscle cells; a novel role for glucose-6-phosphate dehydrogenase

(2010) Ryan J. Mailloux et al.   FASEB JOURNAL

Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species

(2010) Charles Affourtit et al.   FREE RADICAL BIOLOGY AND MEDICINE

Usurping the mitochondrial supremacy: Extramitochondrial sources of reactive oxygen intermediates and their role in beta cell metabolism and insulin secretion

(2010) Joshua P. Gray et al.   TOXICOLOGY MECHANISMS AND METHODS

Tight Coupling between Glucose and Mitochondrial Metabolism in Clonal β-Cells Is Required for Robust Insulin Secretion

(2009) Siri Malmgren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria

(2008) Nadeene Parker et al.   BIOCHEMICAL JOURNAL

On the role of uncoupling protein-2 in pancreatic beta cells

(2008) Charles Affourtit et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

(2008) C. Leloup et al.   DIABETES

Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion

(2007) Charles Affourtit et al.   BIOCHEMICAL JOURNAL

Glucose-stimulated insulin secretion of insulinoma INS-1E cells is associated with elevation of both respiration and mitochondrial membrane potential

(2007) Tomáš Špaček et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY