NAD+/NADH and skeletal muscle mitochondrial adaptations to exercise
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
NAD+/NADH and skeletal muscle mitochondrial adaptations to exercise
Authors
Keywords
-
Journal
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
Volume 303, Issue 3, Pages E308-E321
Publisher
American Physiological Society
Online
2012-03-23
DOI
10.1152/ajpendo.00054.2012
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle
- (2016) Orsolya M. Palacios et al. Aging-US
- Molecular basis for an attenuated mitochondrial adaptive plasticity in aged skeletal muscle
- (2016) Vladimir Ljubicic et al. Aging-US
- Malate–aspartate shuttle and exogenous NADH/cytochrome c electron transport pathway as two independent cytosolic reducing equivalent transfer systems
- (2012) Daniela Isabel Abbrescia et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Nuclear SIRT1 activity, but not protein content, regulates mitochondrial biogenesis in rat and human skeletal muscle
- (2011) Brendon J. Gurd et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Deacetylation of PGC-1α by SIRT1: importance for skeletal muscle function and exercise-induced mitochondrial biogenesis
- (2011) Brendon J. Gurd Applied Physiology Nutrition and Metabolism
- Mitochondrial biogenesis and PGC-1α deacetylation by chronic treadmill exercise: differential response in cardiac and skeletal muscle
- (2011) Ling Li et al. BASIC RESEARCH IN CARDIOLOGY
- PARP-2 Regulates SIRT1 Expression and Whole-Body Energy Expenditure
- (2011) Péter Bai et al. Cell Metabolism
- Fine Tuning Our Cellular Factories: Sirtuins in Mitochondrial Biology
- (2011) Lei Zhong et al. Cell Metabolism
- PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation
- (2011) Péter Bai et al. Cell Metabolism
- CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability
- (2011) Lilia G Noriega et al. EMBO REPORTS
- Compartmentation of NAD+ -dependent signalling
- (2011) Friedrich Koch-Nolte et al. FEBS LETTERS
- Does SIRT1 determine exercise-induced skeletal muscle mitochondrial biogenesis: differences between in vitro and in vivo experiments?
- (2011) Brendon J. Gurd et al. JOURNAL OF APPLIED PHYSIOLOGY
- Sirtuin 1 (SIRT1) Deacetylase Activity Is Not Required for Mitochondrial Biogenesis or Peroxisome Proliferator-activated Receptor-γ Coactivator-1α (PGC-1α) Deacetylation following Endurance Exercise
- (2011) Andrew Philp et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pathways and Subcellular Compartmentation of NAD Biosynthesis in Human Cells
- (2011) Andrey Nikiforov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- In mammalian muscle, SIRT3 is present in mitochondria and not in the nucleus; and SIRT3 is upregulated by chronic muscle contraction in an adenosine monophosphate-activated protein kinase–independent manner
- (2011) Brendon J. Gurd et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD+
- (2011) Zachary Gerhart-Hines et al. MOLECULAR CELL
- Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
- (2011) E. Jing et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Computer-aided studies on the regulation of oxidative phosphorylation during work transitions
- (2011) Bernard Korzeniewski PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Mammalian Sirtuins: Biological Insights and Disease Relevance
- (2010) Marcia C. Haigis et al. Annual Review of Pathology-Mechanisms of Disease
- High-intensity interval training increases SIRT1 activity in human skeletal muscle
- (2010) Brendon J. Gurd et al. Applied Physiology Nutrition and Metabolism
- Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle
- (2010) Carles Cantó et al. Cell Metabolism
- Mitochondrial Biogenesis and Peroxisome Proliferator-Activated Receptor- Coactivator-1 (PGC-1 ) Deacetylation by Physical Activity: Intact Adipocytokine Signaling Is Required
- (2010) L. Li et al. DIABETES
- The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
- (2010) Riekelt H. Houtkooper et al. ENDOCRINE REVIEWS
- SIRT1, AMP-activated protein kinase phosphorylation and downstream kinases in response to a single bout of sprint exercise: influence of glucose ingestion
- (2010) Borja Guerra et al. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
- Muscle contractile activity regulates Sirt3 protein expression in rat skeletal muscles
- (2010) Fumi Hokari et al. JOURNAL OF APPLIED PHYSIOLOGY
- Isoform-specific Targeting and Interaction Domains in Human Nicotinamide Mononucleotide Adenylyltransferases
- (2010) Corinna Lau et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Nicotinamide Phosphoribosyltransferase
- (2010) Maria Pittelli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DYRK1A and DYRK3 Promote Cell Survival through Phosphorylation and Activation of SIRT1
- (2010) Xiumei Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A practical model of low-volume high-intensity interval training induces mitochondrial biogenesis in human skeletal muscle: potential mechanisms
- (2010) Jonathan P. Little et al. JOURNAL OF PHYSIOLOGY-LONDON
- Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor γ coactivator-1α mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle
- (2010) Brendan Egan et al. JOURNAL OF PHYSIOLOGY-LONDON
- SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
- (2010) Matthew D. Hirschey et al. NATURE
- SIRT1 Negatively Regulates the Mammalian Target of Rapamycin
- (2010) Hiyaa Singhee Ghosh et al. PLoS One
- Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis
- (2010) Xingxing Kong et al. PLoS One
- Energy sensing by the AMP-activated protein kinase and its effects on muscle metabolism
- (2010) D. Grahame Hardie PROCEEDINGS OF THE NUTRITION SOCIETY
- Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux
- (2010) Q. Wang et al. SCIENCE
- Regulation of Cellular Metabolism by Protein Lysine Acetylation
- (2010) S. Zhao et al. SCIENCE
- AMP-activated protein kinase in contraction regulation of skeletal muscle metabolism: necessary and/or sufficient?
- (2009) T. E. Jensen et al. Acta Physiologica
- Skeletal muscle NAMPT is induced by exercise in humans
- (2009) Sheila R. Costford et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The Role of Sirtuins in the Control of Metabolic Homeostasis
- (2009) Jiujiu Yu et al. Annals of the New York Academy of Sciences
- Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria
- (2009) Huseyin Cimen et al. BIOCHEMISTRY
- SIRT1-dependent regulation of chromatin and transcription: Linking NAD+ metabolism and signaling to the control of cellular functions
- (2009) Tong Zhang et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- C-terminal binding protein maintains mitochondrial activities
- (2009) J H Kim et al. CELL DEATH AND DIFFERENTIATION
- Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation
- (2009) Christian Dölle et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Successive bouts of cycling stimulates genes associated with mitochondrial biogenesis
- (2009) Charles L. Dumke et al. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
- The NMN/NaMN adenylyltransferase (NMNAT) protein family
- (2009) Corinna Lau Frontiers in Bioscience-Landmark
- Relationship between Sirt1 expression and mitochondrial proteins during conditions of chronic muscle use and disuse
- (2009) Beatrice Chabi et al. JOURNAL OF APPLIED PHYSIOLOGY
- NAD+-dependent Deacetylase SIRT3 Regulates Mitochondrial Protein Synthesis by Deacetylation of the Ribosomal Protein MRPL10
- (2009) Yongjie Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT1 Controls the Transcription of the Peroxisome Proliferator-activated Receptor-γ Co-activator-1α (PGC-1α) Gene in Skeletal Muscle through the PGC-1α Autoregulatory Loop and Interaction with MyoD
- (2009) Ramon Amat et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The deacetylase enzyme SIRT1 is not associated with oxidative capacity in rat heart and skeletal muscle and its overexpression reduces mitochondrial biogenesis
- (2009) Brendon J. Gurd et al. JOURNAL OF PHYSIOLOGY-LONDON
- Cell-cell and intracellular lactate shuttles
- (2009) George A. Brooks JOURNAL OF PHYSIOLOGY-LONDON
- Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats
- (2009) Erika Koltai et al. MECHANISMS OF AGEING AND DEVELOPMENT
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol
- (2009) G Boily et al. ONCOGENE
- CK2 Is the Regulator of SIRT1 Substrate-Binding Affinity, Deacetylase Activity and Cellular Response to DNA-Damage
- (2009) Hyeog Kang et al. PLoS One
- Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins
- (2009) Ivy K. M. Law et al. PROTEOMICS
- Role of NADH/NAD+ transport activity and glycogen store on skeletal muscle energy metabolism during exercise: in silico studies
- (2008) Yanjun Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The human SIRT3 protein deacetylase is exclusively mitochondrial
- (2008) Helen M. Cooper et al. BIOCHEMICAL JOURNAL
- Endurance Exercise as a Countermeasure for Aging
- (2008) I. R. Lanza et al. DIABETES
- The malate-aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast
- (2008) E. Easlon et al. GENES & DEVELOPMENT
- Substrates and Regulation Mechanisms for the Human Mitochondrial Sirtuins Sirt3 and Sirt5
- (2008) Christine Schlicker et al. JOURNAL OF MOLECULAR BIOLOGY
- Endurance exercise increases the SIRT1 and peroxisome proliferator-activated receptor γ coactivator-1α protein expressions in rat skeletal muscle
- (2008) Masataka Suwa et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Modeling of Cellular Metabolism and Microcirculatory Transport
- (2008) Daniel A. Beard et al. MICROCIRCULATION
- SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice
- (2008) Gino Boily et al. PLoS One
- Metabolic Dynamics in Skeletal Muscle during Acute Reduction in Blood Flow and Oxygen Supply to Mitochondria: In-Silico Studies Using a Multi-Scale, Top-Down Integrated Model
- (2008) Ranjan K. Dash et al. PLoS One
- Phosphorylation Regulates SIRT1 Function
- (2008) Tsutomu Sasaki et al. PLoS One
- A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
- (2008) B.-H. Ahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1
- (2008) A. Coste et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sirt1 protects against high-fat diet-induced metabolic damage
- (2008) P. T. Pfluger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started