Rag GTPases and AMPK/TSC2/Rheb mediate the differential regulation of mTORC1 signaling in response to alcohol and leucine

ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signaling

(2011) Jeremiah N. Winter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

RAG GTPases in nutrient-mediated TOR signaling pathway

(2011) Eunjung Kim et al.   CELL CYCLE

Mechanisms Involved in the Coordinate Regulation of mTORC1 by Insulin and Amino Acids

(2011) Michael D. Dennis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipase D Mediates Nutrient Input to Mammalian Target of Rapamycin Complex 1 (mTORC1)

(2011) Limei Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Regulates Mammalian Target of Rapamycin Complex 1 (mTORC1) Activity by Modulating the TSC1/TSC2-Rheb GTPase Pathway

(2011) Sei Yoshida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway

(2010) Jeremiah N. Winter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

Reduced mortality and moderate alcohol consumption: The phospholipase D-mTOR connection

(2010) David A. Foster   CELL CYCLE

Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

(2010) Adem Kalender et al.   Cell Metabolism

Essential amino acid sensing, signaling, and transport in the regulation of human muscle protein metabolism

(2010) Jared M Dickinson et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Downregulation of AMPK Accompanies Leucine- and Glucose-Induced Increases in Protein Synthesis and Insulin Resistance in Rat Skeletal Muscle

(2010) A. K. Saha et al.   DIABETES

Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling Symphony

(2010) Kathryn G. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct anabolic signalling responses to amino acids in C2C12 skeletal muscle cells

(2009) Philip J. Atherton et al.   AMINO ACIDS

Rag proteins regulate amino-acid-induced mTORC1 signalling

(2009) Yasemin Sancak et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1

(2009) C. C. Dibble et al.   MOLECULAR AND CELLULAR BIOLOGY

Acute alcohol intoxication increases atrogin-1 and MuRF1 mRNA without increasing proteolysis in skeletal muscle

(2008) Thomas C. Vary et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

ETOH inhibits embryonic neural stem/precursor cell proliferation via PLD signaling

(2008) Yuko Fujita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin

(2008) A. Toschi et al.   MOLECULAR AND CELLULAR BIOLOGY

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Regulation of TORC1 by Rag GTPases in nutrient response

(2008) Eunjung Kim et al.   NATURE CELL BIOLOGY

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE