Hypertonic stress induces rapid and widespread protein damage in C. elegans

Too salty for worms: hypertonic stress challenges proteostasis networks. Focus on “Hypertonic stress induces rapid and widespread protein damage in C. elegans”

(2011) Thorsten Hoppe   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Protein homeostasis and aging: The importance of exquisite quality control

(2010) Hiroshi Koga et al.   AGEING RESEARCH REVIEWS

Protein Homeostasis and the Phenotypic Manifestation of Genetic Diversity: Principles and Mechanisms

(2010) Daniel F. Jarosz et al.   Annual Review of Genetics

Cellular Proteomes Have Broad Distributions of Protein Stability

(2010) Kingshuk Ghosh et al.   BIOPHYSICAL JOURNAL

Regulation of the members of the mammalian heat shock factor family

(2010) Johanna K. Björk et al.   FEBS Journal

Effect of Trehalose on the Properties of Mutant γPKC, Which Causes Spinocerebellar Ataxia Type 14, in Neuronal Cell Lines and Cultured Purkinje Cells

(2010) Takahiro Seki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Heat Shock Response: Life on the Verge of Death

(2010) Klaus Richter et al.   MOLECULAR CELL

A causative link between the structure of aberrant protein oligomers and their toxicity

(2010) Silvia Campioni et al.   Nature Chemical Biology

Identifying the amylome, proteins capable of forming amyloid-like fibrils

(2010) Lukasz Goldschmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans

(2010) Della C. David et al.   PLOS BIOLOGY

Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3

(2009) Fiona M. Menzies et al.   BRAIN

The evolutionary consequences of erroneous protein synthesis

(2009) D. Allan Drummond et al.   NATURE REVIEWS GENETICS

Genome-wide RNAi screen and in vivo protein aggregation reporters identify degradation of damaged proteins as an essential hypertonic stress response

(2008) Keith P. Choe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences

(2008) Huan-Xiang Zhou et al.   Annual Review of Biophysics

Trehalose impairs aggregation of PrPSc molecules and protects prion-infected cells against oxidative damage

(2008) Florence Béranger et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Guiding Protein Aggregation with Macromolecular Crowding†

(2008) Larissa A. Munishkina et al.   BIOCHEMISTRY

Molecular Genetics and Biomarkers of Polyglutamine Diseases

(2008) Masahisa Katsuno et al.   CURRENT MOLECULAR MEDICINE

The insulin paradox: aging, proteotoxicity and neurodegeneration

(2008) Ehud Cohen et al.   NATURE REVIEWS NEUROSCIENCE

Inhibition of β-amyloid peptide aggregation and neurotoxicity by α-d-mannosylglycerate, a natural extremolyte

(2008) Jungki Ryu et al.   PEPTIDES

Aérosolthérapie dans la mucoviscidose

(2008) J.-C. Dubus et al.   REVUE DES MALADIES RESPIRATOIRES

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE

Hypertonic saline resuscitation from hemorrhagic shock does not impair the neutrophil response to intraabdominal infection

(2008) Giuseppe Papia et al.   SURGERY

C. elegans Model Identifies Genetic Modifiers of α-Synuclein Inclusion Formation During Aging

(2008) Tjakko J. van Ham et al.   PLoS Genetics