Too salty for worms: hypertonic stress challenges proteostasis networks. Focus on “Hypertonic stress induces rapid and widespread protein damage in C. elegans”

Hypertonic stress induces rapid and widespread protein damage in C. elegans

(2011) Kris Burkewitz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The mitochondrial UPR - protecting organelle protein homeostasis

(2010) C. M. Haynes et al.   JOURNAL OF CELL SCIENCE

Protein Quality Control in the Cytosol and the Endoplasmic Reticulum: Brothers in Arms

(2010) Alexander Buchberger et al.   MOLECULAR CELL

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Integration of Clearance Mechanisms: The Proteasome and Autophagy

(2010) E. Wong et al.   Cold Spring Harbor Perspectives in Biology

Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans

(2010) Della C. David et al.   PLOS BIOLOGY

Genome-wide RNAi screen and in vivo protein aggregation reporters identify degradation of damaged proteins as an essential hypertonic stress response

(2008) Keith P. Choe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

(2008) R. I. Morimoto   GENES & DEVELOPMENT

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE