mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON

Nutrition and L and K-enteroendocrine cells

(2011) Ruth Gutierrez-Aguilar et al.   Current Opinion in Endocrinology Diabetes and Obesity

Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-κB dependent AP-1-mediated ICAM-1 expression in breast cancer cells

(2010) Mansoor Ahmed et al.   Molecular Cancer

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

(2010) Shomit Sengupta et al.   MOLECULAR CELL

Leucine metabolism in regulation of insulin secretion from pancreatic beta cells

(2010) Jichun Yang et al.   NUTRITION REVIEWS

Regulation of gastric hormones by systemic rapamycin

(2010) Geyang Xu et al.   PEPTIDES

The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation

(2009) N. Y. Lee et al.   CARCINOGENESIS

Gastric Mammalian Target of Rapamycin Signaling Regulates Ghrelin Production and Food Intake

(2009) Geyang Xu et al.   ENDOCRINOLOGY

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Augmentation of insulin secretion by leucine supplementation in malnourished rats: possible involvement of the phosphatidylinositol 3-phosphate kinase/mammalian target protein of rapamycin pathway

(2009) Eliane Filiputti et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Glucocorticoids increase NPY gene expression in the arcuate nucleus by inhibiting mTOR signaling in rat hypothalamic organotypic cultures

(2009) Hiroshi Shimizu et al.   PEPTIDES

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

(2009) D. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression

(2008) Carolyn L. Buller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanisms of high-glucose/insulin-mediated desensitization of acute insulin-stimulated glucose transport and Akt activation

(2008) Katherine A. Robinson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The role of mTOR in the adaptation and failure of β-cells in type 2 diabetes

(2008) G. Leibowitz et al.   DIABETES OBESITY & METABOLISM

Protein Kinase Cδ Negatively Regulates Hedgehog Signaling by Inhibition of Gli1 Activity

(2008) Qingsong Cai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cotargeting survival signaling pathways in cancer

(2008) Steven Grant   JOURNAL OF CLINICAL INVESTIGATION

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

(2008) A. Y. Choo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA