Article
Environmental Sciences
Jonas Tagt, Emilie Helte, Carolina Donat-Vargas, Susanna C. Larsson, Karl Michaelsson, Alicja Wolk, Marie Vahter, Maria Kippler, Agneta Akesson
Summary: This study assessed the association of urinary cadmium (U-Cd) with fractures, myocardial infarction, heart failure, ischemic stroke, and mortality in postmenopausal women. The results indicated that long-term cadmium exposure might be associated with increased risk of fractures and all-cause mortality at lower levels than previously suggested.
ENVIRONMENT INTERNATIONAL
(2022)
Review
Food Science & Technology
Sina Naghshi, Mohammad Naemi, Omid Sadeghi, Manije Darooghegi Mofrad, Mehrasa Moezrad, Leila Azadbakht
Summary: This study aimed to investigate the association between calcium intake and mortality risk. The findings suggested that moderate intake of total and dietary calcium were inversely associated with mortality risk, while supplemental calcium intake showed no significant association. Nonlinear relationships were observed between calcium intake and all-cause, CVD, and cancer mortality risk.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Nutrition & Dietetics
Emmanouil Mantzouranis, Eleftheria Kakargia, Fotis Kakargias, George Lazaros, Konstantinos Tsioufis
Summary: High protein diets have become popular for weight loss, muscle gain, and improved cardiometabolic parameters. However, few meta-analyses have examined their impact on cardiovascular morbidity and mortality, and have not found significant associations without strict definitions of high protein intake. This study found that high protein consumption does not affect cardiovascular prognosis.
Article
Public, Environmental & Occupational Health
Sara Hallum, Thomas Alexander Gerds, Thomas Steen Gyldenstierne Sehested, Marianne Antonius Jakobsen, Anne Tjonneland, Mads Kamper-Jorgensen
Summary: The presence of male-origin microchimerism in women is associated with a reduced rate of later ischemic heart disease (IHD) development, but not ischemic stroke. This suggests a potential role of microchimerism in women's cardiovascular health, although further studies are needed to confirm these findings.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Nutrition & Dietetics
Guo-Chong Chen, Li-Hua Chen, Yasmin Mossavar-Rahmani, Victor Kamensky, Aladdin H. Shadyab, Bernhard Haring, Robert A. Wild, Brian Silver, Lewis H. Kuller, Yangbo Sun, Nazmus Saquib, Barbara Howard, Linda G. Snetselaar, Marian L. Neuhouser, Matthew A. Allison, Linda Van Horn, JoAnn E. Manson, Sylvia Wassertheil-Smoller, Qibin Qi
Summary: This study found that higher dietary cholesterol intake and egg consumption were modestly associated with increased risk of incident cardiovascular disease and all-cause mortality in postmenopausal women in the United States. Higher intake of these nutrients may lead to elevated risks in this population.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Review
Nutrition & Dietetics
Zuo Hua Gan, Huey Chiat Cheong, Yu-Kang Tu, Po-Hsiu Kuo
Summary: Plant-based diets with higher adherence are associated with lower risks of cardiovascular disease and coronary heart disease. However, the association with stroke risk remains inconclusive. Higher plant-based diet index and healthful PDI scores are related to reduced cardiovascular disease risk.
Article
Clinical Neurology
Zhi Cao, Yabing Hou, Hongxi Yang, Xianhong Huang, Xiaohe Wang, Chenjie Xu
Summary: Sleep behaviors are associated with common mental disorders among individuals with cardiovascular disease. A study conducted on participants from the UK Biobank found that individuals with a healthy sleep pattern had a lower risk of depression, emphasizing the importance of monitoring and improving sleep health in the prevention of common mental disorders among individuals with cardiovascular disease.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Multidisciplinary Sciences
Mareike Ernst, Elmar Braehler, Danielle Otten, Antonia M. Werner, Ana N. Tibubos, Iris Reiner, Felix Wicke, Joerg Wiltink, Matthias Michal, Markus Nagler, Thomas Muenzel, Philipp S. Wild, Jochem Koenig, Norbert Pfeiffer, Andreas Borta, Karl J. Lackner, Manfred E. Beutel
Summary: The study found that inflammation predicted new cases of depression 5 years later, especially in men. Other predictors of new onset depression included younger age, loneliness, smoking (only in men), cancer, and less alcohol consumption (only in women). The study indicates gender differences in the etiology of depressive disorders, with a greater role of physical factors in men.
SCIENTIFIC REPORTS
(2021)
Review
Nutrition & Dietetics
Chengyao Tang, Xiaowen Wang, Li-Qiang Qin, Jia-Yi Dong
Summary: This study investigated the association of the Mediterranean diet with mortality among people with a history of cardiovascular disease, showing that adherence to the diet improved survival in this population. Subgroup analyses indicated a stronger association between the Mediterranean diet and all-cause mortality in Mediterranean areas and shorter duration studies.
Article
Nutrition & Dietetics
Fanny Petermann-Rocha, Carlos Celis-Morales, Jill P. Pell, Frederick K. Ho
Summary: This study compares the cardiovascular risk among vegetarian diets that meet health guidelines, those that do not, and diets that include red meat. The results show that both healthier vegetarians and meat-eaters have a lower risk of cardiovascular disease compared to less healthy meat-eaters. This suggests that future research should consider the overall dietary patterns of vegetarians, rather than solely focusing on meat consumption.
CLINICAL NUTRITION
(2023)
Article
Multidisciplinary Sciences
Jaritza Vega-Solano, Adriana Blanco-Metzler, Karol Madriz-Morales, Eduardo-Augusto Fernandes-Nilson, Marie Eve Labonte
Summary: This study aimed to estimate the impact of reducing salt intake on cardiovascular disease mortality in Costa Rica. The results demonstrated that by following national and international guidelines to reduce salt consumption, between 4% and 13% of deaths due to cardiovascular disease could be prevented or postponed.
Article
Nutrition & Dietetics
Xinyue Lang, Zhiguang Liu, Shofiqul Islam, Guoliang Han, Sumathy Rangarajan, Lap Ah Tse, Maha Mushtaha, Junying Wang, Lihua Hu, Deren Qiang, Yingxuan Zhu, Salim Yusuf, Yang Lin, Bo Hu
Summary: This study aimed to investigate the interaction of depression and diets on cardiovascular diseases (CVD) incident and death in China. The study found that depression significantly increased the risk of CVD in the unhealthy diet group, suggesting that depressive individuals should focus on healthy diets, especially the intake of vegetables and polyunsaturated fatty acids.
Article
Nutrition & Dietetics
Ross L. Prentice, Mary Pettinger, Marian L. Neuhouser, Daniel Raftery, Cheng Zheng, G. A. Nagana Gowda, Ying Huang, Lesley F. Tinker, Barbara Howard, JoAnn E. Manson, Robert Wallace, Yasmin Mossavar-Rahmani, Karen C. Johnson, Johanna W. Lampe
Summary: The study found that a diet high in carbohydrate density is associated with substantially reduced risk of major chronic diseases in a population of US postmenopausal women.
JOURNAL OF NUTRITION
(2021)
Article
Psychiatry
Bingqing Bai, Han Yin, Lan Guo, Huan Ma, Haochen Wang, Fengyao Liu, Yanting Liang, Anbang Liu, Qingshan Geng
Summary: Depression and anxiety have predictive value for noncardiac readmission among patients with angina pectoris. Patients with comorbidity of depression and anxiety have worse prognoses compared to those with single mood symptoms. Additional attention is needed for the initial identification and long-term monitoring of mood symptom comorbidity.
Article
Nutrition & Dietetics
Hairong Li, Xufen Zeng, Yingying Wang, Zhuang Zhang, Yu Zhu, Xiude Li, Anla Hu, Qihong Zhao, Wanshui Yang
Summary: Increased intake of a plant-based diet rich in healthier plant foods is associated with lower mortality risk, whereas a plant-based diet that emphasizes less-healthy plant foods is associated with high mortality risk among US adults.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Carl J. Pepine, C. Noel Bairey Merz
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Steven M. M. Smith, Almut G. G. Winterstein, Matthew J. J. Gurka, Marta G. G. Walsh, Shailina Keshwani, Anne M. M. Libby, William R. R. Hogan, Carl J. J. Pepine, Rhonda M. M. Cooper-DeHoff
Summary: This study reveals significant variation in initial antihypertensive prescribing among new users, highlighting a gap between current guideline recommendations and real-world implementation in early hypertension care.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Letter
Cardiac & Cardiovascular Systems
Judy M. Luu, Pankaj Malhotra, Galen Cook-Wiens, Carl J. Pepine, Eileen M. Handberg, Steven E. Reis, Nathaniel Reichek, Vera Bittner, Janet Wei, Sheryl F. Kelsey, Reddy Sailaja Marpuri, George Sopko, C. Noel Bairey Merz
Editorial Material
Cardiac & Cardiovascular Systems
Mario Gaudino, Stephen E. Fremes, Roxana Mehran, C. Noel Bairey Merz
Article
Public, Environmental & Occupational Health
Scott M. Vouri, Earl J. Morris, Marta Walsh, Jessica Agalliu, Alyssa Dempsey, Leonie Hochleitner, Matthew R. Muschett, Stephan Schmidt, Carl J. Pepine, Steven M. Smith
Summary: This study aimed to comprehensively assess prescribing cascades related to statin medications. The results identified potential prescribing cascades, including laxatives, analgesics, and cephalosporins. These findings are important for reducing the occurrence of prescribing cascades.
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
(2023)
Article
Cardiac & Cardiovascular Systems
Jing Li, Elaine M. Richards, Ramakumar Tummala, Carl J. Pepine, Mohan K. Raizada, Tao Yang
Summary: Hypertension is associated with gut dysbiosis and altered intestinal immunity. Using sorting techniques and gene sequencing, we found significant differences in IgA(+) and IgA(-) bacteria between hypertensive and normotensive rats. We also identified several IgA-coated bacteria that were negatively correlated with various pathways involved in immune response and epithelium development.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
David L. DeRemer, Nam K. Nguyen, Avirup Guha, Faraz S. Ahmad, Rhonda M. Cooper-DeHoff, Carl J. Pepine, Michael G. Fradley, Yan Gong
Summary: This study evaluated the differences in cardiac surveillance among different racial and ethnic groups among survivors of cancer after exposure to anthracycline-based treatment. The study found that African American and Hispanic patients had lower participation rates in cardiac surveillance. These results suggest that healthcare providers need to be aware of social inequities and take measures to ensure recommended cardiac surveillance after anthracycline therapy.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Psychology, Multidisciplinary
Kristie M. Harris, Allison E. Gaffey, Joseph E. Schwartz, David S. Krantz, Matthew M. Burg
Summary: This study examined the stability and variability of the Perceived Stress Scale (PSS) using data from two independent samples. The results showed that between-person variance accounted for a large proportion of the total variance in PSS scores, indicating that the PSS may primarily measure a stable perception of stress. However, within-person variance was also observed. These findings suggest that the PSS may have a more stable characteristic in assessing individuals' perception of stress.
ANNALS OF BEHAVIORAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Sadiya S. Khan, Lucia C. Petito, Xiaoning Huang, Katharine Harrington, Rebecca B. McNeil, Natalie A. Bello, C. Noel Bairey Merz, Eliza C. Miller, Rupa Ravi, Christina Scifres, Janet M. Catov, Victoria L. Pemberton, Jasmina Varagic, Phyllis C. Zee, Lynn M. Yee, Mitali Ray, Jin Kyung Kim, Abbi D. Lane-Cordova, Jennifer Lewey, Lauren H. Theilen, George R. Saade, Philip Greenland, William A. Grobman
Summary: This study found a significant association between early pregnancy obesity and postpartum hypertension, hyperlipidemia, and diabetes risk. Adverse pregnancy outcomes were related to increased incidence of postpartum hypertension and hyperlipidemia. However, these adverse pregnancy outcomes only partially mediated the association between early pregnancy obesity and postpartum hypertension.
CIRCULATION RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Robert F. Hamburger, Yasmeen Taha, Mohammed Ruzieh, James R. Clugston, Eileen M. Handberg, Fred Reifsteck, Matthew W. Martinez, Carl J. Pepine, Katherine M. Edenfield
Summary: This study investigated the effects of intense training on cardiac remodeling in American collegiate football players. The findings showed that training was associated with increases in chamber sizes, left atrial size, and aortic root diameter.
CLINICAL CARDIOLOGY
(2023)
Article
Pharmacology & Pharmacy
Grace Hsin-Min Wang, Earl Morris, Scott M. Vouri, Shailina Keshwani, Stephan Schmidt, Carl J. Pepine, Steven M. Smith
Summary: This study aims to identify modifiable statin characteristics associated with lower risk of prescribing cascades. The results show that compared to low-intensity statins, moderate- or high-intensity statins and the choice of individual statin agents are associated with increased risk of prescribing cascades.
Article
Medicine, General & Internal
Yasmeen K. Taha, Jennifer R. Dungan, Michael T. Weaver, Ke Xu, Eileen M. Handberg, Carl J. Pepine, C. Noel Bairey Merz
Summary: Identifying ischemic heart disease (IHD) in women based on symptoms is challenging, as women are more likely to experience non-cardiac symptoms. More than 50% of women with suspected ischemia have no obstructive coronary disease, leading to impaired outcomes during follow-up. A study aimed to identify symptoms that can predict non-obstructive coronary artery disease (INOCA) in women with clinical evidence of coronary ischemia. The study found that age, left side chest pain, chest discomfort, neck pain, and palpitations had a positive relationship with INOCA, while impending doom and pain in the jaw, left or bilateral arm, and right hand were inversely related to INOCA. The best-fit model accurately predicted INOCA based on age and symptom presentation about 72% of the time.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Dimitrios Tsiachris, Christos-Konstantinos Antoniou, Ioannis Doundoulakis, Panagiota Manolakou, Demetrios Sougiannis, Athanasios Kordalis, Konstantinos A. Gatzoulis, Gian-Battista Chierchia, Carlo de Asmundis, Christodoulos Stefanadis, Konstantinos Tsioufis
Summary: Nowadays, cryoballoon (CB) has become an established alternative to radio frequency (RF) ablation for pulmonary vein isolation (PVI), with the ability to isolate PVs in a single application. In a study on over 1000 consecutive patients, our center optimized the CB PVI procedure. It is expected that future guidelines will recommend CB as the first-line PVI for patients with paroxysmal AF and a class I indication. In a long-term follow-up of the EARLY-AF trial, CB showed a lower incidence of persistent atrial fibrillation compared to anti-arrhythmic drugs.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
Article
Psychology, Clinical
Nicholas R. Moorehead, Jeffrey L. Goodie, David S. Krantz
Summary: This study investigates the bidirectional relationships between depressive symptoms and metabolic syndrome (MetS). MetS more consistently predicts depressive symptoms over time compared to the reverse. The relationships between MetS and depressive symptoms are moderated by race and sex, but not influenced by health behaviors.
