Markers in the 15q24 nicotinic receptor subunit gene cluster (CHRNA5-A3-B4) predict severity of nicotine addiction and response to smoking cessation therapy

Convergent Evidence that Choline Acetyltransferase Gene Variation is Associated with Prospective Smoking Cessation and Nicotine Dependence

(2010) Riju Ray et al.   NEUROPSYCHOPHARMACOLOGY

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes

(2009) Nancy L. Saccone et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Variants in nicotinic acetylcholine receptors α5 and α3 increase risks to nicotine dependence

(2009) Xiangning Chen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Transcription Deregulation at the 15q25 Locus in Association with Lung Adenocarcinoma Risk

(2009) F. S. Falvella et al.   CLINICAL CANCER RESEARCH

An appraisal of smoking cessation aids

(2009) Kavita Mundey   CURRENT OPINION IN PULMONARY MEDICINE

A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy

(2009) Rachel M. Freathy et al.   HUMAN MOLECULAR GENETICS

Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15

(2009) Kaisu Keskitalo et al.   HUMAN MOLECULAR GENETICS

Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5

(2009) Jen C. Wang et al.   HUMAN MOLECULAR GENETICS

Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals

(2009) Esther H Lips et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes

(2009) Timothy B. Baker et al.   NICOTINE & TOBACCO RESEARCH

Genome-Wide and Candidate Gene Association Study of Cigarette Smoking Behaviors

(2009) Neil Caporaso et al.   PLoS One

Psychological mediators of bupropion sustained-release treatment for smoking cessation

(2008) Danielle E. McCarthy et al.   ADDICTION

Extended cognitive behavior therapy for cigarette smoking cessation

(2008) Joel D. Killen et al.   ADDICTION

Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with ‘pleasurable buzz’ during early experimentation with smoking

(2008) Richard Sherva et al.   ADDICTION

Variants in Nicotinic Receptors and Risk for Nicotine Dependence

(2008) Laura Jean Bierut et al.   AMERICAN JOURNAL OF PSYCHIATRY

A Risk Allele for Nicotine Dependence in CHRNA5 Is a Protective Allele for Cocaine Dependence

(2008) Richard A. Grucza et al.   BIOLOGICAL PSYCHIATRY

In search of causal variants: refining disease association signals using cross-population contrasts

(2008) Nancy L Saccone et al.   BMC GENETICS

Nicotinic Receptor Gene Variants Influence Susceptibility to Heavy Smoking

(2008) V. L. Stevens et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Smokers with the CHRNA Lung Cancer-Associated Variants Are Exposed to Higher Levels of Nicotine Equivalents and a Carcinogenic Tobacco-Specific Nitrosamine

(2008) L. Le Marchand et al.   CANCER RESEARCH

Receptor-mediated tobacco toxicity: acceleration of sequential expression of α5 and α7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke

(2008) Juan Arredondo et al.   FASEB JOURNAL

Nicotinic acetylcholine receptor β2 subunit gene implicated in a systems-based candidate gene study of smoking cessation

(2008) David V. Conti et al.   HUMAN MOLECULAR GENETICS

Accounting for ancestry: population substructure and genome-wide association studies

(2008) C. Tian et al.   HUMAN MOLECULAR GENETICS

Smoking and Smoking Cessation in Relation to Mortality in Women

(2008) Stacey A. Kenfield   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The CHRNA5-A3 Region on Chromosome 15q24-25.1 Is a Risk Factor Both for Nicotine Dependence and for Lung Cancer

(2008) Margaret R. Spitz et al.   JNCI-Journal of the National Cancer Institute

Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

(2008) J C Wang et al.   MOLECULAR PSYCHIATRY

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

(2008) Rayjean J. Hung et al.   NATURE

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

(2008) Christopher I Amos et al.   NATURE GENETICS

A Candidate Gene Approach Identifies the CHRNA5-A3-B4 Region as a Risk Factor for Age-Dependent Nicotine Addiction

(2008) Robert B. Weiss et al.   PLoS Genetics