Do the Lactotripeptides Isoleucine-Proline-Proline and Valine-Proline-Proline Reduce Systolic Blood Pressure in European Subjects? A Meta-Analysis of Randomized Controlled Trials

Efficacy and Tolerability of Fimasartan, a New Angiotensin Receptor Blocker, Compared With Losartan (50/100 mg): A 12-Week, Phase III, Multicenter, Prospective, Randomized, Double-Blind, Parallel-Group, Dose Escalation Clinical Trial With an Optional 12-Week Extension Phase in Adult Korean Patients With Mild-to-Moderate Hypertension

(2012) Sang Eun Lee et al.   CLINICAL THERAPEUTICS

A spread containing bioactive milk peptides Ile–Pro–Pro and Val–Pro–Pro, and plant sterols has antihypertensive and cholesterol-lowering effects

(2012) Anu M. Turpeinen et al.   Food & Function

Milk casein-derived tripeptides, VPP and IPP induced NO production in cultured endothelial cells and endothelium-dependent relaxation of isolated aortic rings

(2011) Tatsuhiko Hirota et al.   HEART AND VESSELS

Lactotripeptides effect on office and 24-h ambulatory blood pressure, blood pressure stress response, pulse wave velocity and cardiac output in patients with high-normal blood pressure or first-degree hypertension: a randomized double-blind clinical trial

(2011) Arrigo FG Cicero et al.   HYPERTENSION RESEARCH

Humanin vivostudy of the renin-angiotensin-aldosterone system and the sympathetic activity after 8 weeks daily intake of fermented milk

(2010) Lotte Usinger et al.   CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING

The antihypertensive effect of fermented milk in individuals with prehypertension or borderline hypertension

(2010) L Usinger et al.   JOURNAL OF HUMAN HYPERTENSION

Blood pressure lowering effect of lactotripeptides assumed as functional foods: a meta-analysis of current available clinical trials

(2010) A F G Cicero et al.   JOURNAL OF HUMAN HYPERTENSION

Perindopril-based blood pressure lowering reduces major vascular events in Asian and Western participants with cerebrovascular disease: the PROGRESS trial

(2010) Hisatomi Arima et al.   JOURNAL OF HYPERTENSION

Hemodynamic Effects of Lactotripeptides from Casein Hydrolysate in Mediterranean Normotensive Subjects and Patients with High-Normal Blood Pressure: A Randomized, Double-Blind, Crossover Clinical Trial

(2010) Arrigo F.G. Cicero et al.   JOURNAL OF MEDICINAL FOOD

Dose‐dependent lowering of blood pressure by dairy peptides in mildly hypertensive subjects

(2009) Peter W. de Leeuw et al.   BLOOD PRESSURE

Study of the mechanism of antihypertensive peptides VPP and IPP in spontaneously hypertensive rats by DNA microarray analysis

(2009) Naoya Yamaguchi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The PHARAO study: prevention of hypertension with the angiotensin-converting enzyme inhibitor ramipril in patients with high-normal blood pressure – a prospective, randomized, controlled prevention trial of the German Hypertension League

(2009) Stephan Lüders et al.   JOURNAL OF HYPERTENSION

Antihypertensive and cholesterol-lowering effects of a spread containing bioactive peptides IPP and VPP and plant sterols

(2009) A.M. Turpeinen et al.   Journal of Functional Foods

Enzymatically hydrolyzed lactotripeptides do not lower blood pressure in mildly hypertensive subjects

(2008) Kim van der Zander et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Lactotripeptides do not lower ambulatory blood pressure in untreated whites: results from 2 controlled multicenter crossover studies

(2008) Linda AJ van Mierlo et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Ethnic Differences in Cardiovascular Drug Response

(2008) Julie A. Johnson   CIRCULATION

Fermented lactotripeptides-containing milk lowers daytime blood pressure in high normal-to-mild hypertensive subjects

(2008) K van der Zander et al.   JOURNAL OF HUMAN HYPERTENSION

Studies on the molecular recognition between bioactive peptides and angiotensin-converting enzyme

(2008) A.S. Pina et al.   JOURNAL OF MOLECULAR RECOGNITION

Effect of milk tripeptides on blood pressure: A meta-analysis of randomized controlled trials

(2008) Jia-Ying Xu et al.   NUTRITION

Lactotripeptides Show No Effect on Human Blood Pressure

(2007) Mariëlle F. Engberink et al.   HYPERTENSION