Article
Nutrition & Dietetics
Pardis Khalili, Atieh Mirzababaei, Faezeh Abaj, Shakila Ansari, Asma Rajabi Harsini, Mahya Mehri Hajmir, Cain C. T. Clark, Khadijeh Mirzaei
Summary: This study aimed to assess the association between dietary factors and the severity, duration, and frequency of migraine headaches. The results showed that people with high adherence to a healthy diet had a 43% reduction in the duration of migraines. However, no significant association was found between diet and the frequency and severity of migraines.
Article
Geriatrics & Gerontology
Mitch J. Duncan, Elizabeth G. Holliday, Stina Oftedal, Matthew Buman, Wendy J. Brown
Summary: The study found that mid-aged women who were physically inactive and had sleep difficulties were more likely to develop hypertension, while sleep difficulties were not associated with hypertension among physically active women. Physical activity appeared to protect against the increased risk of hypertension in women with sleeping difficulties.
Article
Medicine, General & Internal
Leah M. Santacroce, Nancy E. Avis, Alicia B. Colvin, Kristine Ruppert, Carrie Karvonen-Gutierrez, Daniel H. Solomon
Summary: This study investigated the physiological and functional changes in midlife women's health and identified factors associated with improvements in physical health and function. Approximately 15% of women experienced clinically important improvements over an 11-year period.
Article
Gastroenterology & Hepatology
David Schnadower, Karen J. O'Connell, John M. VanBuren, Cheryl Vance, Phillip Tarr, Suzanne Schuh, Katrina Hurley, Alexander J. Rogers, Naveen Poonai, Cindy G. Roskind, Seema R. Bhatt, Serge Gouin, Prashant Mahajan, Cody S. Olsen, Elizabeth C. Powell, Ken Farion, Robert E. Sapien, Thomas H. Chun, Stephen B. Freedman
Summary: This study investigated the efficacy of probiotics in childhood acute gastroenteritis and found that the duration and severity of symptoms before treatment did not affect the efficacy of probiotics. The results suggest that in children aged 3-48 months with acute gastroenteritis, probiotics are not influenced by the duration or frequency of symptoms before treatment.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Psychology, Multidisciplinary
Andela Dosic, Danijela Zivkovic, Zoran Milanovic, Mladen ivkovic, Ljiljana Bjelakovic, Marija Bratic, Sasa Pantelic
Summary: The study aims to investigate the relationship between physical activity level, BMI, and quality of life. Results indicate that high- and moderate-intensity physical activity benefit physical health, with moderate PA showing higher significance levels. Additionally, elderly women with higher BMI values achieve better results in the environmental domain of quality of life.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Oncology
Nita H. Mukand, Naomi Y. Ko, Nadia A. Nabulsi, Colin C. Hubbard, Brian C-H Chiu, Kent F. Hoskins, Gregory S. Calip
Summary: This study found that low physical health-related quality of life and physical functioning are associated with an increased risk of contralateral breast cancer. Efforts to understand and minimize declines in physical functioning post-breast cancer diagnosis are important.
Article
Immunology
Patricia Zadorosnei Rebutini, Aline Cristina Zanchettin, Emanuele Therezinha Schueda Stonoga, Daniele Margarita Marani Pra, Andre Luiz Parmegiani de Oliveira, Felipe da Silva Deziderio, Aline Simoneti Fonseca, Julio Cesar Honorio Dagostini, Elisa Carolina Hlatchuk, Isabella Naomi Furuie, Jessica da Silva Longo, Barbara Maria Cavalli, Carolina Lumi Tanaka Dino, Viviane Maria de Carvalho Hessel Dias, Ana Paula Percicote, Meri Bordignon Nogueira, Sonia Mara Raboni, Newton Sergio de Carvalho, Cleber Machado-Souza, Lucia de Noronha
Summary: This study compared the placental morphological and morphometric changes in pregnant women infected with SARS-CoV-2 with those of non-infected pregnant women. The results showed that symptomatic women in the COVID-19 group were more likely to have adverse fetal outcomes, with more frequent histopathologic findings of maternal and fetal vascular malperfusion. There were no significant differences in morphometric changes between the COVID-19 group and the Control group, except for slightly more accentuated deposition of villous fibrin in the COVID-19 group.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Environmental Sciences
Gema Cabrera-Dominguez, Maria de la Calle, Gloria Herranz Carrillo, Santiago Ruvira, Pilar Rodriguez-Rodriguez, Silvia M. Arribas, David Ramiro-Cortijo
Summary: Sleep, mental health, and physical activity are crucial for women's wellbeing. During the lactation period, poor sleep quality, decreased physical activity, and lower social support may lead to inadequate mental health adjustment.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Geriatrics & Gerontology
Fangyu Liu, Amal A. Wanigatunga, Pei-Lun Kuo, Vadim Zipunnikov, Eleanor M. Simonsick, Luigi Ferrucci, Jennifer A. Schrack
Summary: Physical activity becomes more fragmented with age, and poorer energy cost and capacity may be associated with this. Higher cost-to-capacity ratio and lower energy capacity may lead to more fragmented physical activity, especially among those less active or aged >= 70 years.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Multidisciplinary Sciences
Maria Fernanda Naufel, Amanda Paula Pedroso, Lila Missae Oyama, Monica Marques Telles, Helena Hachul, Eliane Beraldi Ribeiro
Summary: The study found that postmenopausal overweight women with severe depression symptoms had higher levels of total and acylated ghrelin, and positive associations with acylated ghrelin and BMI. This is the first demonstration of an association between acylated ghrelin and the severity of depression symptoms in postmenopausal women, suggesting a potential physiological response or causal factor in this mental disorder.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Ren Dodge, Eric W. Jones, Haolong Zhu, Benjamin Obadia, Daniel J. Martinez, Chenhui Wang, Andres Aranda-Diaz, Kevin Aumiller, Zhexian Liu, Marco Voltolini, Eoin L. Brodie, Kerwyn Casey Huang, Jean M. Carlson, David A. Sivak, Allan C. Spradling, William B. Ludington
Summary: The gut is exposed to various bacteria from the diet and environment, but the composition of the gut microbiome remains stable over time in different host species. This study used gnotobiotic Drosophila to investigate the stability of different strains of bacteria in the fly gut. The researchers found that a physical niche in the foregut selectively binds bacteria with strain-specificity, stabilizing their colonization. Initial colonization by Lactobacillus species remodels the niche to favor secondary colonization by unrelated commensals. These findings provide insights into the establishment and stability of a multi-species intestinal microbiome.
NATURE COMMUNICATIONS
(2023)
Article
Environmental Sciences
Seyedeh Mahboobeh Jafari, Mohammad Reza Nikoo, Mojtaba Sadegh, Mingjie Chen, Amir H. H. Gandomi
Summary: Climate change has led to an increase in the severity and frequency of droughts. High-resolution spatiotemporal data is essential for effective planning and management to mitigate the adverse impacts of droughts. The TMPA dataset, although accurate with fine resolution, has a limited temporal span for drought studies.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Neurosciences
Shilpa C. Rao, Yadi Li, Brittany Lapin, Sreya Pattipati, Kamalini Ghosh Galvelis, Anna Naito, Nicolas Gutierrez, Thiago Peixoto Leal, Amira Salim, Philippe A. Salles, Maria De Leon, Ignacio F. Mata
Summary: Parkinson's disease (PD) is an age-related neurological disorder that shows differences in risk, progression, and severity between men and women. This study aimed to identify women-specific health experiences associated with PD severity by developing and distributing a women-specific questionnaire and creating multivariable models. The results found significant associations between major depressive disorder, perinatal depression, natural childbirth, LRRK2 genotype, B12 deficiency, total hysterectomy, and increased PD severity. This study provides important insights into the etiology of PD and highlights the role of sex-specific experiences.
NPJ PARKINSONS DISEASE
(2023)
Article
Public, Environmental & Occupational Health
Bin Feng, Ke Xu, Panpan Zhou
Summary: This study found a positive association between vigorous physical activity and life satisfaction among adolescents aged 11-15. Both boys and girls who engaged in more frequent vigorous physical activity per week were more likely to have higher life satisfaction. In addition, more hours of vigorous physical activity were also associated with better life satisfaction.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Clinical Neurology
Yi-huan Chen, Fen Xue, Shou-fen Yu, Xiao-sa Li, Ling Liu, Yan-yan Jia, Wen-jun Yan, Qing-rong Tan, Hua-ning Wang, Zheng-wu Peng
Summary: This study reveals the differences in gut microbiota composition and function in female patients with depression, suggesting potential microbial targets and biomarkers that may aid in the diagnosis and treatment of depression.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Obstetrics & Gynecology
Rebecca L. Smith, Lisa M. Gallicchio, Jodi A. Flaws
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2018)
Article
Geriatrics & Gerontology
Catheryne Chiang, Lisa Gallicchio, Howard Zacur, Sue Miller, Jodi A. Flaws, Rebecca L. Smith
Article
Reproductive Biology
Chan Jin Park, Radwa Barakat, Alexander Ulanov, Zhong Li, Po-Ching Lin, Karen Chiu, Sherry Zhou, Pablo Perez, Jungyeon Lee, Jodi Flaws, ChemYong Jay Ko
REPRODUCTIVE TOXICOLOGY
(2019)
Review
Biochemistry & Molecular Biology
Andressa Gonsioroski, Vasiliki E. Mourikes, Jodi A. Flaws
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Environmental Sciences
Karen Chiu, Shah Tauseef Bashir, Liying Gao, Jessica Gutierrez, Maria R. C. de Godoy, Jenny Drnevich, Christopher J. Fields, Isaac Cann, Jodi A. Flaws, Romana A. Nowak
Summary: Subacute exposure to DEHP during pregnancy significantly affected the cecal microbiome in pregnant mice, increasing alpha diversity and altering beta diversity. DEHP exposure led to an increase in the relative abundance of Bacteroidetes and a decrease in the relative abundance of Firmicutes and Deferribacteres. In addition, DEHP exposure significantly altered 14 functional pathways, but did not have a significant impact on fertility and birth outcomes.
Article
Environmental Sciences
Karen K. Chiu, Shah Tauseef Bashir, Ahmed M. Abdel-Hamid, Lindsay V. Clark, Mary J. Laws, Isaac Cann, Romana A. Nowak, Jodi A. Flaws
Summary: This study examines the impact of DiNP exposure on the gut microbiota and immune-related factors, revealing that DiNP exposure can alter the composition of the gut microbiota and that the gut contains microbes capable of degrading DiNP.
Article
Environmental Sciences
Diana C. Pacyga, Brad A. Ryva, Romana A. Nowak, Serdar E. Bulun, Ping Yin, Zhong Li, Jodi A. Flaws, Rita S. Strakovsky
Summary: This study investigated the association between phthalates and fibroids and found that each two-fold increase in sigma DEHP or sigma AA was associated with a 13% and 16% greater risk of prior fibroid diagnosis in women. These associations were strongest in women who were overweight/obese and in those diagnosed with fibroids within 5 years before phthalate assessment.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Environmental Sciences
Endia J. Fletcher, Ramses Santacruz-Marquez, Vasiliki E. Mourikes, Alison M. Neff, Mary J. Laws, Jodi A. Flaws
Summary: This review discusses the effects of phthalate mixtures on the female reproductive system. Phthalates have been found to target the ovaries, disrupting normal reproductive function and potentially affecting folliculogenesis and steroidogenesis. Additionally, phthalates can cross the placental barrier and impact fetal development. However, the specific effects of phthalate mixtures on the ovary and female reproduction are still not well understood.
Review
Biochemistry & Molecular Biology
Nitya Shree, Zehuan Ding, Jodi Flaws, Mahua Choudhury
Summary: The prevalence of poor metabolic health is increasing exponentially worldwide, with exposure to environmental chemicals, such as endocrine-disrupting chemicals (EDCs), gaining attention as a contributing factor. Recent reports suggest that non-coding RNAs, specifically microRNAs (miRs), may play a vital role in this phenomenon.
Review
Environmental Sciences
Xing Zhang, Jodi A. Flaws, Michael J. Spinella, Joseph Irudayaraj
Summary: Endocrine disrupting chemicals (EDCs) are exogenous substances that can alter the endocrine function of an organism, leading to adverse effects on growth, development, metabolism, and reproductive function. Studies have shown that EDCs can cause proteinuria, affect glomeruli and renal tubules, and even lead to diabetes and renal fibrosis in both animals and humans. This review discusses the renal accumulation of specific EDCs, such as dioxins, per- and polyfluoroalkyl substances (PFAS), bisphenol A (BPA), and phthalates, and explores how exposure to these EDCs can result in renal lesions and diseases, including cancer. The regulation of target genes and activation of related pathways by typical EDCs are also summarized.
Article
Environmental Sciences
Vasiliki E. Mourikes, Ramses Santacruz Marquez, Ashley Deviney, Alison M. Neff, Mary J. Laws, Jodi A. Flaws
Summary: Imidacloprid is a neonicotinoid pesticide used in agriculture, gardening, and veterinary medicine. It has the potential to accumulate in the environment and harm non-targeted species. Imidacloprid and its metabolite desnitro-imidacloprid have different effects on follicle growth and steroidogenesis. These compounds also alter the expression of genes related to hormone regulation and apoptosis.
Article
Genetics & Heredity
Clotilde Maurice, Mathieu Dalvai, Romain Lambrot, Astrid Deschenes, Marie-Pier Scott-Boyer, Serge McGraw, Donovan Chan, Nancy Cote, Ayelet Ziv-Gal, Jodi A. Flaws, Arnaud Droit, Jacquetta Trasler, Sarah Kimmins, Janice L. Bailey
Summary: The study found that paternal exposure to POPs pollutants can impact the development and pregnancy outcomes of offspring, with this effect potentially explained by sperm DNA methylation. Experimental results suggest that the paternal methylome is sensitive to the environment, with some perturbations persisting for at least two subsequent generations.
Article
Reproductive Biology
Saniya Rattan, Emily Brehm, Liying Gao, Sarah Niermann, Jodi A. Flaws
BIOLOGY OF REPRODUCTION
(2018)
Article
Endocrinology & Metabolism
Zuzana Drobna, Anne D. Henriksen, Jennifer T. Wolstenholme, Catalina Montiel, Philip S. Lambeth, Stephen Shang, Erin P. Harris, Changqing Zhou, Jodi A. Flaws, Mazhar Adli, Emilie F. Rissman
Article
Endocrinology & Metabolism
Kirsten S. Eckstrum, Whitney Edwards, Annesha Banerjee, Wei Wang, Jodi A. Flaws, John A. Katzenellenbogen, Sung Hoon Kim, Lori T. Raetzman
